Herbert Aaron Hauptman (February 14, 1917 – October 23, 2011) was an American

mathematician A mathematician is someone who uses an extensive knowledge of mathematics in their work, typically to solve mathematical problems. Mathematicians are concerned with numbers, data, quantity, structure, space, models, and change. History On ...

and

Nobel laureate The Nobel Prizes ( sv, Nobelpriset, no, Nobelprisen) are awarded annually by the Royal Swedish Academy of Sciences, the Swedish Academy, the Karolinska Institutet, and the Norwegian Nobel Committee to individuals and organizations who make o ...

. He pioneered and developed a mathematical method that has changed the whole field of

chemistry Chemistry is the scientific study of the properties and behavior of matter. It is a natural science that covers the elements that make up matter to the compounds made of atoms, molecules and ions: their composition, structure, proper ...

and opened a new era in research in determination of molecular structures of crystallized materials. Today, Hauptman's direct methods, which he continued to improve and refine, are routinely used to solve complicated structures. It was the application of this mathematical method to a wide variety of chemical structures that led the

Royal Swedish Academy of Sciences The Royal Swedish Academy of Sciences ( sv, Kungliga Vetenskapsakademien) is one of the royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special responsibility for prom ...

to name Hauptman and

Jerome Karle Jerome Karle (born Jerome Karfunkle; June 18, 1918 – June 6, 2013) was an American physical chemist. Jointly with Herbert A. Hauptman, he was awarded the Nobel Prize in Chemistry in 1985, for the direct analysis of crystal structures using X-ra ...

recipients of the 1985

Nobel Prize in Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...

Life

He was born in to a Jewish family in

New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...

, the oldest child of Leah (Rosenfeld) and Israel Hauptman. He was married to Edith Citrynell since November 10, 1940, with two daughters, Barbara (1947) and Carol (1950). He was interested in

science Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence ...

and mathematics from an early age which he pursued at Townsend Harris High School, graduated from the

City College of New York The City College of the City University of New York (also known as the City College of New York, or simply City College or CCNY) is a public university within the City University of New York (CUNY) system in New York City. Founded in 1847, Cit ...

(1937) and obtained an M.A. degree in mathematics from

Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...

in 1939. After the war he started a collaboration with

at the

Naval Research Laboratory The United States Naval Research Laboratory (NRL) is the corporate research laboratory for the United States Navy and the United States Marine Corps. It was founded in 1923 and conducts basic scientific research, applied research, technologic ...

in Washington, D.C. and at the same time enrolled in the Ph.D. program at the

University of Maryland, College Park The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland. Founded in 1856, UMD is the flagship institution of the University System of ...

. He received his Ph.D. from the

University of Maryland The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland. Founded in 1856, UMD is the flagship institution of the University System of ...

in 1955 in physics, which is part of the

University of Maryland College of Computer, Mathematical, and Natural Sciences The College of Computer, Mathematical, and Natural Sciences (CMNS) at the University of Maryland, College Park, is home to ten academic departments and a dozen interdisciplinary research centers and institutes. CMNS is one of 13 schools and colleg ...

. This combination of mathematics and

physical chemistry Physical chemistry is the study of macroscopic and microscopic phenomena in chemical systems in terms of the principles, practices, and concepts of physics such as motion, energy, force, time, thermodynamics, quantum chemistry, statistica ...

expertise enabled them to tackle head-on the phase problem of

X-ray crystallography X-ray crystallography is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions. By measuring the angles ...

. His work on this problem was criticized because, at the time, the problem was believed unsolvable. By 1955 he had received his Ph.D. in mathematics, and they had laid the foundations of the direct methods in X-ray crystallography. Their 1953 monograph, "Solution of the Phase Problem I. The Centrosymmetric Crystal", contained the main ideas, the most important of which was the introduction of

probabilistic Probability is the branch of mathematics concerning numerical descriptions of how likely an event is to occur, or how likely it is that a proposition is true. The probability of an event is a number between 0 and 1, where, roughly speaking, ...

methods through a development of the

Sayre equation In crystallography, the Sayre equation, named after David Sayre who introduced it in 1952, is a mathematical relationship that allows one to calculate probable values for the phases of some diffracted beams. It is used when employing direct metho ...

. In 1970 he joined the crystallographic group of the Medical Foundation of Buffalo of which he was Research Director in 1972. During the early years of this period he formulated the neighborhood principle and extension concept. These theories were further developed during the following decades. In 2003, as an

atheist Atheism, in the broadest sense, is an absence of belief in the existence of deities. Less broadly, atheism is a rejection of the belief that any deities exist. In an even narrower sense, atheism is specifically the position that there no ...

and

secular humanist Secular humanism is a philosophy, belief system or life stance that embraces human reason, secular ethics, and philosophical naturalism while specifically rejecting religious dogma, supernaturalism, and superstition as the basis of morality ...

, he was one of 22 Nobel laureates who signed the Humanist Manifesto.

Works

Hauptman has authored over 170 publications, including journal articles, research papers, chapters and books. In 1970, Hauptman joined the crystallographic group of the

Hauptman-Woodward Medical Research Institute The Hauptman-Woodward Medical Research Institute (HWI) is an independent, not-for-profit, biomedical research facility located in the Buffalo Niagara Medical Campus. Its focus is on structural biology with a strong history in methods developmen ...

(formerly the Medical Foundation of Buffalo) of which he became Research Director in 1972. Until his death, he served as President of the

as well as Research Professor in the Department of Biophysical Sciences and Adjunct Professor in the Department of Computer Science at the

University at Buffalo The State University of New York at Buffalo, commonly called the University at Buffalo (UB) and sometimes called SUNY Buffalo, is a public research university with campuses in Buffalo and Amherst, New York. The university was founded in 18 ...

. Prior to coming to Buffalo, he worked as a mathematician and supervisor in various departments at the

from 1947. He received his B.S. from

, M.S. from

and Ph.D. from the

Awards and titles

*Belden Prize in Mathematics,

, 1936 *Scientific Research Society of America, Pure Science Award,

, 1959 *President,

Philosophical Society of Washington Founded in 1871, the Philosophical Society of Washington is the oldest scientific society in Washington, D.C. It continues today as PSW Science. Since 1887, the Society has met regularly in the assembly hall of the Cosmos Club. In the Club's p ...

, 1969–1970 *President of the Association of Independent Research Institutes, 1979–1980 *Patterson Award in 1984 given by the American Crystallographic Association *

, 1985 (jointly with

) *Honorary degrees from the

in 1985 *Honorary degree from CCNY in 1986 *Citizen of the Year Award, Buffalo Evening News, 1986 *Norton Medal, SUNY, 1986 *Schoellkopf Award, American Chemical Society (Western New York Chapter) 1986 *Golden Plate Award of the

American Academy of Achievement The American Academy of Achievement, colloquially known as the Academy of Achievement, is a non-profit educational organization that recognizes some of the highest achieving individuals in diverse fields and gives them the opportunity to meet ...

, 1986 *Cooke Award, SUNY, 1987 *Establishment of the Eccles-Hauptman Student Award, SUNY in 1987 *Election to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...

in 1988 *Humanist Laureate Award from the International Humanist and Ethical Union in 1988 *Honorary degree from the

University of Parma The University of Parma ( it, Università degli Studi di Parma, UNIPR) is a public university in Parma, Emilia-Romagna, Italy. It is organised in nine departments. As of 2016 the University of Parma has about 26,000 students. History During the ...

, Italy in 1989 *Honorary degree from the

D'Youville College D'Youville University (D'Youville or DYU) is a private university in Buffalo, New York. It was founded as D'Youville College in 1908 and named by the Grey Nuns after the patroness saint Marie-Marguerite d'Youville. As of Fall 2020 D'Youville Col ...

Buffalo, New York Buffalo is the second-largest city in the U.S. state of New York (behind only New York City) and the seat of Erie County. It is at the eastern end of Lake Erie, at the head of the Niagara River, and is across the Canadian border from Sou ...

in 1989 *Honorary degree from

Bar-Ilan University Bar-Ilan University (BIU, he, אוניברסיטת בר-אילן, ''Universitat Bar-Ilan'') is a public research university in the Tel Aviv District city of Ramat Gan, Israel. Established in 1955, Bar Ilan is Israel's second-largest academi ...

Israel Israel (; he, יִשְׂרָאֵל, ; ar, إِسْرَائِيل, ), officially the State of Israel ( he, מְדִינַת יִשְׂרָאֵל, label=none, translit=Medīnat Yīsrāʾēl; ), is a country in Western Asia. It is situated ...

in 1990 *Honorary degree from

Technical University of Lodz Technical may refer to: * Technical (vehicle), an improvised fighting vehicle * Technical analysis, a discipline for forecasting the future direction of prices through the study of past market data * Technical drawing, showing how something is ...

Poland Poland, officially the Republic of Poland, is a country in Central Europe. It is divided into 16 administrative provinces called voivodeships, covering an area of . Poland has a population of over 38 million and is the fifth-most populou ...

in 1992 *Honorary degree from Queen's University, Kingston, Canada in 1993 *Honorary degree from SUNY at Buffalo,

in 2009

References

External links

*
Dr Hauptman's CV
*[https://web.archive.org/web/20090124000656/http://buffalofilmfestival.com/aboutus/artsandscienceadvisors.html Board of Science Advisors, The Buffalo International Film Festival, Buffalo, NY, United States] {{DEFAULTSORT:Hauptman, Herbert A. 1917 births 2011 deaths Nobel laureates in Chemistry American Nobel laureates Members of the United States National Academy of Sciences 20th-century American mathematicians 21st-century American mathematicians American people of German-Jewish descent Jewish American scientists Jewish chemists Jewish American atheists Columbia University alumni American physical chemists University of Maryland, College Park alumni City College of New York alumni Townsend Harris High School alumni Secular humanists Mathematicians from New York (state)