Hans Fischer
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Hans Fischer (; 27 July 1881 – 31 March 1945) was a German
organic chemist Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J. ...
and the recipient of the 1930
Nobel Prize for Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...
"for his researches into the constitution of haemin and chlorophyll and especially for his synthesis of haemin."


Biography


Early years

Fischer was born on July 27,1881 in Höchst on river Main, now a city district of
Frankfurt Frankfurt, officially Frankfurt am Main (; Hessian: , " Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on it ...
located in Germany. His parents were Dr. Eugen Fischer, Director of the firm of Kalle & Co,
Wiesbaden Wiesbaden () is a city in central western Germany and the capital of the state of Hesse. , it had 290,955 inhabitants, plus approximately 21,000 United States citizens (mostly associated with the United States Army). The Wiesbaden urban area ...
, and Privatdozent at the Technical High School, Stuttgart, and Anna Herdegen was his mother. He went to a primary school in Stuttgart, and later to the "Humanistisches Gymnasium" in
Wiesbaden Wiesbaden () is a city in central western Germany and the capital of the state of Hesse. , it had 290,955 inhabitants, plus approximately 21,000 United States citizens (mostly associated with the United States Army). The Wiesbaden urban area ...
, matriculating in 1899. He read chemistry and
medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pr ...
, first at the
University of Lausanne The University of Lausanne (UNIL; french: links=no, Université de Lausanne) in Lausanne, Switzerland was founded in 1537 as a school of Protestant theology, before being made a university in 1890. The university is the second oldest in Switzer ...
and then at
Marburg Marburg ( or ) is a university town in the German federal state (''Bundesland'') of Hesse, capital of the Marburg-Biedenkopf district (''Landkreis''). The town area spreads along the valley of the river Lahn and has a population of approxima ...
. He graduated in 1904 obtaining his chemistry degree, 2 years later in 1906 he licensed for medicine and in 1908 he qualified for his
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. ...
including the Nobel Lecture, December 11, 1930 ''On Haemin and the Relationships between Haemin and Chlorophyll'' which he applied to the University of Munich.


Career

He worked first at a Medical Clinic in
Munich Munich ( ; german: München ; bar, Minga ) is the capital and most populous city of the German state of Bavaria. With a population of 1,558,395 inhabitants as of 31 July 2020, it is the third-largest city in Germany, after Berlin and Ha ...
and then at the First Berlin Chemical Institute under
Emil Fischer Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of draw ...
. He returned to Munich in 1911 and qualified as lecturer on internal medicine one year later. In 1913, he became a lecturer in
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
at the Physiological Institute in Munich. In 1916, he became Professor of Medical Chemistry at the
University of Innsbruck The University of Innsbruck (german: Leopold-Franzens-Universität Innsbruck; la, Universitas Leopoldino Franciscea) is a public research university in Innsbruck, the capital of the Austrian federal state of Tyrol, founded on October 15, 1669. ...
and from there he went to the
University of Vienna The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich hist ...
in 1918. From 1921 until his death, he held the position of Professor of Organic Chemistry at the
Technical University of Munich The Technical University of Munich (TUM or TU Munich; german: Technische Universität München) is a public research university in Munich, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Establis ...
. Fischer's scientific work was mostly concerned with the investigation of the pigments in
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the cir ...
, bile, and also chlorophyll in leaves, as well as with the chemistry of pyrrole from which these pigments are derived. Of special importance was his synthesis of bilirubin and haemin. He received many honors for this work, and received the
Nobel Prize The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfr ...
in 1930. The
lunar crater Lunar craters are impact craters on Earth's Moon. The Moon's surface has many craters, all of which were formed by impacts. The International Astronomical Union currently recognizes 9,137 craters, of which 1,675 have been dated. History The wor ...
Fischer Fischer is a German occupational surname, meaning fisherman. The name Fischer is the fourth most common German surname. The English version is Fisher. People with the surname A * Abraham Fischer (1850–1913) South African public official * A ...
was named after him (and
Hermann Emil Fischer Hermann Emil Louis Fischer (; 9 October 1852 – 15 July 1919) was a German chemist and 1902 recipient of the Nobel Prize in Chemistry. He discovered the Fischer esterification. He also developed the Fischer projection, a symbolic way of dra ...
) in 1976. Hans Fisher had mapped the composition of a hem group. In 1929 Fischer succeeded in producing the substance and proving that its ring has a central atom of iron, as he also continued studying other pigmented substances of a biological importance of biochemistry such as chlorophyll, the color that plays part in a plants photosynthesis. Fischer also unraveled the bile pigments biliverdin (which causes the yellowish color characteristic of bruised skin) and bilirubin (which yellows skin in jaundice cases), and synthesized them in 1942 and 1944, successively. He conducted microanalyses of more than 60,000 chemical substance, and had won the Nobel Prize for Chemistry in 1930. The person that sparked Fischer's interest was von Muller, his former professor and supervisor whom interests were in pyrrole pigments by inviting Fischer to work with him at the well-known Second Medical Clinic in Munich in 1910. Under Muller, he began to examine the composition of the bile pigment bilirubin, something he would continue to be engaged in during the decades that followed. Fischer's succession also came with difficulty's as many of his experiments seemed to have failed but with time Fischer was able to perfect his acknowledgement with is failed attempts.


Personal life

Fischer married Wiltrud Haufe around his 50's in the year 1935. Fischer was a man whom dedicated almost "exclusively" to his work. He continued his scientific research during Germany's Nazi era, and committed suicide on Easter Sunday in 1945, after his laboratory and life's work had been destroyed by the bombing in the last days of World War II.


Honours

*Fellow of the
Academy of Sciences Leopoldina The German National Academy of Sciences Leopoldina (german: Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften), short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founded ...
(1919) * Privy Councillor (1925) *Liebig Memorial Medal (1929) *
Nobel Prize for Chemistry ) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "M ...
(1930) *
Honorary doctorate An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad hon ...
,
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of high ...
(1936) *
Davy Medal The Davy Medal is awarded by the Royal Society of London "for an outstandingly important recent discovery in any branch of chemistry". Named after Humphry Davy, the medal is awarded with a monetary gift, initially of £1000 (currently £2000). H ...
of the
Royal Society of London The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
(1937)


Literature

* * * * *


References


External links

* * including the Nobel Lecture, December 11, 1930
{{DEFAULTSORT:Fischer, Hans 1881 births 1945 suicides German Nobel laureates Organic chemists 20th-century German chemists Nobel laureates in Chemistry Scientists from Frankfurt People from Hesse-Nassau University of Marburg alumni Academics of the University of Innsbruck Academics of the University of Vienna Technical University of Munich faculty Suicides in Germany 1945 deaths