Putative G-protein coupled receptor 42 (previously termed FFAR1L, FFAR3L, GPR41L, and GPR42P) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''GPR42''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
The human GPR gene is located at the same site as the human ''FFAR1, FFAR,'' and ''FFAR3'' genes, i.e., on the
long (i.e., "q") arm of
chromosome 19
Chromosome 19 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 19 spans more than 58.6 million base pairs, the building material of DNA. It is considered the most gene-rich chromosom ...
at position 23.33 (notated as 19q23.33). This gene appears to be a
segmental duplication
Low copy repeats (LCRs), also known as segmental duplications (SDs), are highly homologous sequence elements within the eukaryotic genome.
Repeats
The repeats, or duplications, are typically 10–300 kb in length, and bear greater than 95% sequ ...
of the ''FFAR3'' gene. The human ''GPR42'' gene codes for several proteins with a FFAR3-like structure but their expression in various cell types and tissues as well as their activities and functions have not yet been clearly defined in any scientific publication followed by
PubMed
PubMed is a free search engine accessing primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institutes of Health maintain t ...
as of 2023.
See also
*
Free fatty acid receptors
*
Free fatty acid receptor 3
References
Further reading
*
*
*
External links
*
G protein-coupled receptors
{{transmembranereceptor-stub