GNRHR2

Putative gonadotropin-releasing hormone II receptor is a protein that in humans is encoded by the ''GNRHR2'' gene.

Function

The receptor for gonadotropin releasing hormone 2 (GnRH2) is encoded by the GnRH2 receptor (GnRHR2) gene. In non-hominoid primates and non-mammalian vertebrates, GnRHR2 encodes a seven-transmembrane G protein-coupled receptor. However, in human, the N-terminus of the predicted protein contains a frameshift and premature stop codon. In human, GnRHR2 transcription occurs but whether the gene produces a functional C-terminus, C-terminal multi-transmembrane protein is currently unresolved. Alternative splice variants have been reported. An untranscribed pseudogene of GnRHR2 is also on chromosome 14.

See also

* Gonadotropin-releasing hormone receptor

References

Further reading

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External links

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G protein-coupled receptors
{{transmembranereceptor-stub