Flossie Cohen (1925–2004) was an Indian-born

pediatric Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...

immunologist who spent most of her career at the

Children's Hospital of Michigan Children's Hospital of Michigan (CHM) is a for-profit, pediatric acute care hospital located in Detroit, Michigan. The hospital has 227 beds and is affiliated with both the Wayne State University School of Medicine and the Michigan State Universit ...

. She was also a professor at the

Wayne State University School of Medicine The Wayne State University School of Medicine (WSUSOM) is the medical school of Wayne State University, a public research university in Detroit, Michigan. It enrolls more than 1,500 students in undergraduate medical education, master's degree, P ...

Biography

Cohen was born in 1925 in

Kolkata Kolkata (, or , ; also known as Calcutta , the official name until 2001) is the capital of the Indian state of West Bengal, on the eastern bank of the Hooghly River west of the border with Bangladesh. It is the primary business, comme ...

, India. She later migrated to the United States and studied medicine at the

University of Buffalo The State University of New York at Buffalo, commonly called the University at Buffalo (UB) and sometimes called SUNY Buffalo, is a public research university with campuses in Buffalo and Amherst, New York. The university was founded in 18 ...

, graduating in 1950. She completed her residency in pediatrics at the Brooklyn Jewish Hospital, and moved to

Michigan Michigan () is a U.S. state, state in the Great Lakes region, Great Lakes region of the Upper Midwest, upper Midwestern United States. With a population of nearly 10.12 million and an area of nearly , Michigan is the List of U.S. states and ...

in 1953 to join the

. There, she began research in the field of pediatric and

neonatal An infant or baby is the very young offspring of human beings. ''Infant'' (from the Latin word ''infans'', meaning 'unable to speak' or 'speechless') is a formal or specialised synonym for the common term ''baby''. The terms may also be used to ...

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see the ...

. She set up the hospital's

clinical immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there ...

laboratory and its service for clinical immunology and

rheumatology Rheumatology (Greek ''ῥεῦμα'', ''rheûma'', flowing current) is a branch of medicine devoted to the diagnosis and management of disorders whose common feature is inflammation in the bones, muscles, joints, and internal organs. Rheumatolog ...

; she directed both departments until her retirement in 1992. She was also a professor at the

. In 1972, Cohen was the co-author of a landmark study that was the first to demonstrate a biochemical basis for

severe combined immunodeficiency Severe combined immunodeficiency (SCID), also known as Swiss-type agammaglobulinemia, is a rare genetic disorder characterized by the disturbed development of functional T cells and B cells caused by numerous genetic mutations that result in diffe ...

. She continued to study immunodeficiency disorders, and with the outbreak of the

HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...

epidemic in the 1980s, she started an HIV clinic at the Children's Hospital of Michigan in 1985. She was also involved in clinical trials for perinatal transmission of HIV. In 1975, Cohen became the first person in Michigan to successfully perform a

bone marrow transplant Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce ...

in a child. She was also the first person to

fluoresce Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation. It is a form of luminescence. In most cases, the emitted light has a longer wavelength, and therefore a lower photon energy, tha ...

red blood cell Red blood cells (RBCs), also referred to as red cells, red blood corpuscles (in humans or other animals not having nucleus in red blood cells), haematids, erythroid cells or erythrocytes (from Greek ''erythros'' for "red" and ''kytos'' for "holl ...

s. She was inducted into the

Michigan Women's Hall of Fame The Michigan Women's Hall of Fame (MWHOF) honors distinguished women, both historical and contemporary, who have been associated with the U.S. state of Michigan. The hall of fame was founded in 1983 by Gladys Beckwith and is sponsored by the Michi ...

in 1994 for her achievements in medicine and science, and died in 2004.

References

{{DEFAULTSORT:Cohen, Flossie 1925 births 2004 deaths American immunologists Indian immunologists American pediatricians Women pediatricians Indian paediatricians Medical doctors from Kolkata Physicians from Michigan Indian emigrants to the United States University at Buffalo alumni Wayne State University faculty Women scientists from West Bengal 20th-century Indian medical doctors 20th-century Indian women scientists Indian women medical doctors 20th-century American women physicians 20th-century American physicians American women academics 21st-century American women

Biography

See also

References