People

* Mark Twain, pen name of American writer Samuel Langhorne Clemens (1835–1910) * Norman Twain (1930–2016), American film producer * Shania Twain (born 1965), Canadian singer-songwriter

Places

* Twain, California, a census-designated place in Plumas County * Douglas River, formerly named Twain, in New Zealand

Other uses

* TWAIN, a communication standard for computer software and digital imaging devices {{disambig, geo, surname