A38 or A-38 may refer to:
* A38 (dairy product), a fermented dairy product sold in Denmark
* A38 (ship), a party boat on the Danube in Budapest, Hungary
* A38 motorway (Netherlands)
* A38 road (England)
* A38 (Sydney), an arterial route in Sydney, Australia
* Bundesautobahn 38, an autobahn in Germany
* English Opening, Encyclopaedia of Chess Openings code
* Aero A.38, a Czech airliner of the 1930s
* Iceberg A-38
* Valiant tank, a WWII-era prototype British tank
* XA-38 Grizzly, a prototype American attack aircraft of the 1940s
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