Frizzled-2 (Fz-2) is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
that in humans is encoded by the ''FZD2''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Members of the '
frizzled
Frizzled is a family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol.
Species distribution
Fr ...
' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the ''FZD2'' gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary.
References
Further reading
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External links
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G protein-coupled receptors
{{transmembranereceptor-stub