Proto-oncogene tyrosine-protein kinase FER is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
that in humans is encoded by the ''FER''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors.
Interactions
FER (gene) has been shown to
interact
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with
TMF1
TATA element modulatory factor is a protein that in humans is encoded by the ''TMF1'' gene.
Interactions
TMF1 has been shown to interact with FER and Androgen receptor
The androgen receptor (AR), also known as NR3C4 (nuclear receptor sub ...
and
Cortactin
Cortactin (from "''cortical actin'' binding protein") is a monomeric protein located in the cytoplasm of cells that can be activated by external stimuli to promote polymerization and rearrangement of the actin cytoskeleton, especially the actin c ...
.
References
Further reading
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Tyrosine kinases
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