FACIT collagen (Fibril Associated Collagens with Interrupted Triple helices) is a type of
collagen
Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whol ...
which is also a
proteoglycan
Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached glycosaminoglycan (GAG) chain(s). The point of attachment is a serine (Ser) residue to whic ...
.
FACIT collagens include collagen types IX, XII, XIV, XIX,
and XXI.
COL22A1
COL22A1 is a human gene encoding for collagen. The associated protein is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during muscle contraction
Muscle contraction is the act ...
is also included in this class.
See also
*
Triple helix
**
Collagen helix
In molecular biology, the collagen triple helix or type-2 helix is the main secondary structure of various types of fibrous collagen, including type I collagen. In 1954, Ramachandran & Kartha (13, 14) advanced a structure for the collagen tripl ...
References
Structural proteins
*
{{Fibrous proteins