Eugene Koonin
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Eugene Viktorovich Koonin (Russian: Евге́ний Ви́кторович Ку́нин; born October 26, 1956) is a Russian-American biologist and Senior Investigator at the
National Center for Biotechnology Information The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. Th ...
(NCBI). He is a recognised expert in the field of
evolutionary Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variati ...
and
computational biology Computational biology refers to the use of data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the ...
.


Education

Koonin gained a
Master of Science A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast t ...
in 1978 and a
PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * '' Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. al ...
in 1983 in
molecular biology Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and phys ...
, both from the Department of Biology at
Moscow State University M. V. Lomonosov Moscow State University (MSU; russian: Московский государственный университет имени М. В. Ломоносова) is a public research university in Moscow, Russia and the most prestigious ...
. His PhD thesis, titled "Multienzyme organization of encephalomyocarditis virus replication complexes", was supervised by Vadim I. Agol.


Research

From 1985 until 1991, Koonin worked as a research scientist in computational biology in the Institutes of
Poliomyelitis Poliomyelitis, commonly shortened to polio, is an infectious disease caused by the poliovirus. Approximately 70% of cases are asymptomatic; mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe sym ...
and Microbiology at the
USSR Academy of Medical Sciences The USSR Academy of Medical Sciences (russian: Акаде́мия медици́нских нау́к СССР) was the highest scientific and medical organization founded in the Soviet Union founded in 1944. Its successor is the Russian Academy of ...
, studying virus biochemistry and bacterial genetics. In 1991, Koonin moved to the NCBI, where he has held a Senior Investigator position since 1996. Koonin's principal research goals include the comparative analysis of sequenced genomes and automatic methods for genome-scale annotation of gene functions. He also researches in the application of comparative
genomics Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
for phylogenetic analysis, reconstruction of ancestral life forms and building large-scale evolutionary scenarios, as well as mathematical modeling of
genome evolution Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient ...
. Koonin's research also investigates computational study of the major transitions in the evolution of life (such as the origin of
eukaryote Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacter ...
s), the evolution of eukaryotic signaling and developmental pathways from the comparative-genomic perspective.


Career

Koonin has worked as Adjunct Professor at the
Georgia Institute of Technology The Georgia Institute of Technology, commonly referred to as Georgia Tech or, in the state of Georgia, as Tech or The Institute, is a public research university and institute of technology in Atlanta, Georgia. Established in 1885, it is part ...
,
Boston University Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original cam ...
and the
University of Haifa The University of Haifa ( he, אוניברסיטת חיפה Arabic: جامعة حيفا) is a university located on Mount Carmel in Haifa, Israel. Founded in 1963, the University of Haifa received full academic accreditation in 1972, becoming ...
. As of 2014, Koonin serves on the advisory editorial board of '' Trends in Genetics'', and is co-Editor-in-Chief of the open access journal ''
Biology Direct ''Biology Direct'' is an online open access scientific journal that publishes original, peer-reviewed research papers, reviews, hypotheses, comments and discovery notes in biology. The journal is published by BioMed Central. The journal follows a ...
''. He served on the editorial board of ''
Bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
'' from 1999 until 2001. Koonin is also an advisory board member in bioinformatics at
Faculty of 1000 F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than b ...
. In 2016 he was elected to the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
. In 2016,
Semantic Scholar Semantic Scholar is an artificial intelligence–powered research tool for scientific literature developed at the Allen Institute for AI and publicly released in November 2015. It uses advances in natural language processing to provide summaries ...
AI program included Koonin on its list of top ten most influential biomedical researchers.


Political positions

In February 2022, he signed an open letter by Russian scientists condemning the
2022 Russian invasion of Ukraine On 24 February 2022, in a major escalation of the Russo-Ukrainian War, which began in 2014. The invasion has resulted in tens of thousands of deaths on both sides. It has caused Europe's largest refugee crisis since World War II. A ...
, and renounced his membership in the
Russian Academy of Sciences The Russian Academy of Sciences (RAS; russian: Росси́йская акаде́мия нау́к (РАН) ''Rossíyskaya akadémiya naúk'') consists of the national academy of Russia; a network of scientific research institutes from across t ...
out of protest.Global Science Community Condemns Russian Invasion of Ukraine
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References


Selected bibliography

* HAL Id
02861246
* * *


External links

* {{DEFAULTSORT:Koonin, Eugene 1956 births Living people Theoretical biologists Russian bioinformaticians Extended evolutionary synthesis Human Genome Project scientists Members of the United States National Academy of Sciences Foreign Members of the Russian Academy of Sciences 21st-century American biologists Moscow State University alumni Russian activists against the 2022 Russian invasion of Ukraine