End-systolic volume (ESV) is the volume of blood in a ventricle at the end of contraction, or systole, and the beginning of filling, or

diastole Diastole ( ) is the relaxed phase of the cardiac cycle when the chambers of the heart are re-filling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventri ...

. ESV is the lowest volume of blood in the ventricle at any point in the cardiac cycle. The main factors that affect the end-systolic volume are afterload and the contractility of the heart. __TOC__

Uses

End systolic volume can be used clinically as a measurement of the adequacy of cardiac emptying, related to systolic function. On an electrocardiogram, or ECG, the end-systolic volume will be seen at the end of the T wave. Clinically, ESV can be measured using two-dimensional echocardiography, MRI ( magnetic resonance tomography) or cardiac CT ( computed tomography) or SPECT (single photon emission computed tomography).

Sample values

Along with end-diastolic volume, ESV determines the stroke volume, or output of blood by the heart during a single phase of the cardiac cycle. The stroke volume is the difference between the end-diastolic volume and the end-systolic volume. The end-systolic values in the table below are for the left ventricle: The right ventricular end-systolic volume (RVESV) normally ranges between 50 and 100 mL.

References

Cardiovascular physiology {{circulatory-stub