End-diastolic volume
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In
cardiovascular physiology Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular"). These subjects are sometimes addressed separately, under the names cardiac physiolog ...
, end-diastolic volume (EDV) is the volume of blood in the right or left ventricle at end of filling in
diastole Diastole ( ) is the relaxed phase of the cardiac cycle when the chambers of the heart are re-filling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventri ...
which is ammount of blood present in ventricle at the end of diastole systole. Because greater EDVs cause greater distention of the ventricle, ''EDV'' is often used synonymously with '' preload'', which refers to the length of the
sarcomere A sarcomere (Greek σάρξ ''sarx'' "flesh", μέρος ''meros'' "part") is the smallest functional unit of striated muscle tissue. It is the repeating unit between two Z-lines. Skeletal muscles are composed of tubular muscle cells (called mus ...
s in
cardiac muscle Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle th ...
prior to contraction (systole). An increase in EDV increases the preload on the heart and, through the Frank-Starling mechanism of the heart, increases the amount of blood ejected from the ventricle during systole ( stroke volume). __TOC__


Sample values

The right ventricular end-diastolic volume (RVEDV) ranges between 100 and 160 mL. The right ventricular end-diastolic volume index (RVEDVI) is calculated by RVEDV/ BSA and ranges between 60 and 100 mL/m2.


See also

* End-systolic volume * Stroke volume


References

{{DEFAULTSORT:End-Diastolic Volume Cardiovascular physiology