Elizabeth F. Neufeld
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Elizabeth Fondal Neufeld (born September 27, 1928) is a French-American geneticist whose research has focused on the genetic basis of metabolic disease in humans.


Life

Neufeld and her Russian Jewish family emigrated to the United States from Paris in 1940; they had left Europe as refugees to escape Nazi persecution. The family settled in New York, where she attended
Hunter College High School Hunter College High School is a secondary school located in the Carnegie Hill neighborhood on the Upper East Side of Manhattan. It is administered by Hunter College of the City University of New York (CUNY). Hunter is publicly funded, and there ...
before graduating from
Queens College Queens College (QC) is a public college in the Queens borough of New York City. It is part of the City University of New York system. Its 80-acre campus is primarily located in Flushing, Queens. It has a student body representing more than 170 ...
in 1948 with a
Bachelor of Science A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University o ...
. She went on to work as a research assistant at the
Jackson Laboratory The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by a eugenicist. It employs more than 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, ...
in
Bar Harbor, Maine Bar Harbor is a resort town on Mount Desert Island in Hancock County, Maine, United States. As of the 2020 census, its population is 5,089. During the summer and fall seasons, it is a popular tourist destination and, until a catastrophic fire ...
, looking at blood disorders in
mice A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus'' ...
. Later on, she attended graduate school at
University of California, Berkeley The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant un ...
, where she earned a Ph.D. in 1956 for her work on nucleotides and complex carbohydrates. Neufeld has been widely recognized for her contributions to science. She is a member of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...
and the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
. She was elected to the
American Academy of Arts and Sciences The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, a ...
in 1977. Neufeld has been awarded the
Wolf Prize The Wolf Prize is an international award granted in Israel, that has been presented most years since 1978 to living scientists and artists for ''"achievements in the interest of mankind and friendly relations among people ... irrespective of nati ...
, the
Albert Lasker Award for Clinical Medical Research Lasker-DeBakey Clinical Medical Research Award is one of four annual awards presented by the Lasker Foundation. The Lasker-DeBakey award is given to honor outstanding work for the understanding, diagnosis, prevention, treatment, and cure of disea ...
, and was awarded the
National Medal of Science The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral and social scienc ...
in 1994 "for her contributions to the understanding of the lysosomal storage diseases, demonstrating the strong linkage between basic and applied scientific investigation." Neufeld retired in 2004 from
UCLA The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California ...
as Chair of the Department of Biological Chemistry, a position she occupied since 1984.


Personal life

Elizabeth Fondal married Benjamin S. Neufeld in 1951; they had two children together.Benjamin S. Neufeld September 5, 1926 - March 28, 2020
Mount Sinai Parks. Accessed Feb. 27, 2022.


Selected publications

Ohmi K, Greenberg DS, Rajavel KS, Ryazantsev S, Li HH, Neufeld EF., (2003),
Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB.
''Proceedings of the National Academy of Sciences of the United States of America''. 100: 1902-7. PMID 12576554 DOI: 10.1073/Pnas.252784899 Elizabeth F. Neufeld, W.Z. Hassid,(1963),
Biosynthesis of Saccharides from Glycopyranosyl Esters of Nucleotides (“Sugar Nucleotides”)
Editor(s): Melville L. Wolfrom, R. Stuart Tipson, Advances in Carbohydrate Chemistry,Academic Press,Volume 18,1963,Pages 309-356,ISSN 0096-5332,ISBN 9780120072187, https://doi.org/10.1016/S0096-5332(08)60246-5.


See also

*
Inborn error of metabolism Inborn errors of metabolism form a large class of genetic diseases involving congenital disorders of enzyme activities. The majority are due to defects of single genes that code for enzymes that facilitate conversion of various substances ( subst ...


References


Further reading

* * Nicole Kresge, Robert D. Simoni, Robert L. Hill, (2007),
Lysosomal Storage Disease Factors: the Work of Elizabeth F. Neufeld
, Journal of Biological Chemistry, Vol 282, Issue 20,Pages e15-e17,https://doi.org/10.1073/pnas.252784899


External links


Home Page at UCLA
{{DEFAULTSORT:Neufeld, Elizabeth F. 1928 births French emigrants to the United States 20th-century French Jews Hunter College High School alumni Queens College, City University of New York alumni University of California, Berkeley alumni American geneticists National Medal of Science laureates Living people Wolf Prize in Medicine laureates Members of the United States National Academy of Sciences Jewish American scientists Recipients of the Lasker-DeBakey Clinical Medical Research Award Scientists from New York (state) 21st-century American Jews Members of the American Philosophical Society Members of the National Academy of Medicine