E621 may refer to:

Rail locomotives

FS Class E.621 The FS Class E.621 was a class of five electric locomotives of the Italian State Railways (FS). They were rebuilt in 1947 from FS Class E.620, which was originally built in 1925. The main change was conversion from 650 V DC third rail to 3,000 V DC ...

, a 1947 Italian model *E621, a 2013 Japanese

E6 Series Shinkansen The is a Japanese Shinkansen high-speed train type operated by East Japan Railway Company (JR East) on '' Komachi'' " mini-shinkansen" services on the Tōhoku Shinkansen and Akita Shinkansen from Tokyo to since 16 March 2013. A pre-series s ...

railcar

Other uses

* Monosodium glutamate, a food flavour enhancer (labelled ''E621'' in the EU) *e621.net, a booru-style furry fandom imageboard owned by the CEO of

Bad Dragon Bad Dragon Enterprises, Inc. is an American manufacturer of fantasy-themed sex toys, primarily targeted at members of the furry fandom. Products are sold online and at conventions. The CEO of Bad Dragon, Jan "Varka" Mulders, also owns the booru ...

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