DeMille or De Mille is a surname. Notable people with the surname include:
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Agnes De Mille, American dance and choreographer
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Beatrice deMille, English-born American playwright and screenwriter
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Cecil B. DeMille, American film director
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Constance Adams DeMille, American actress
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Evelyn de Mille (1919–2013), Canadian bookseller
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Henry Churchill de Mille, American playwright
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James De Mille, Canadian writer
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Katherine DeMille, Canadian-born American actress
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Nelson DeMille, American author
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Oliver DeMille, American author and educator
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Richard de Mille, American journalist and author
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William C. deMille, American screenwriter and film director
{{surname, DeMille