Christopher Carl Goodnow (born 19 September 1959) is an immunology researcher and the current Executive Director of the

Garvan Institute of Medical Research The Garvan Institute of Medical Research is an Australian biomedical research institute located in , Sydney, New South Wales. Founded in 1963 by the Sisters of Charity as a research department of St Vincent's Hospital, it is now one of Australi ...

. He holds the Bill and Patricia Ritchie Foundation Chair and is a Conjoint Professor in the Faculty of Medicine at

UNSW The University of New South Wales (UNSW), also known as UNSW Sydney, is a public research university based in Sydney, New South Wales, Australia. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive ...

Sydney Sydney ( ) is the capital city of the state of New South Wales, and the most populous city in both Australia and Oceania. Located on Australia's east coast, the metropolis surrounds Sydney Harbour and extends about towards the Blue Mounta ...

. He holds dual Australian and US

citizenship Citizenship is a "relationship between an individual and a state to which the individual owes allegiance and in turn is entitled to its protection". Each state determines the conditions under which it will recognize persons as its citizens, and ...

Career

Born in

Hong Kong Hong Kong ( (US) or (UK); , ), officially the Hong Kong Special Administrative Region of the People's Republic of China (abbr. Hong Kong SAR or HKSAR), is a List of cities in China, city and Special administrative regions of China, special ...

in 1959 to Robert Goodnow and Jacqueline J. Goodnow AC, Goodnow grew up in

Rome , established_title = Founded , established_date = 753 BC , founder = King Romulus ( legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption ...

and

Washington DC ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, ...

before moving to

, Australia as a teenager. He trained in

veterinary medicine Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutri ...

and surgery,

immunochemistry Immunochemistry is the study of the chemistry of the immune system. This involves the study of the properties, functions, interactions and production of the chemical components (antibodies/immunoglobulins, toxin, epitopes of proteins like CD4, a ...

and

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see ther ...

at the

University of Sydney The University of Sydney (USYD), also known as Sydney University, or informally Sydney Uni, is a public research university located in Sydney, Australia. Founded in 1850, it is the oldest university in Australia and is one of the country's si ...

and in DNA technology at

Stanford University Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is conside ...

. After doctoral studies at

Melbourne Melbourne ( ; Boonwurrung/ Woiwurrung: ''Narrm'' or ''Naarm'') is the capital and most populous city of the Australian state of Victoria, and the second-most populous city in both Australia and Oceania. Its name generally refers to a metro ...

Walter and Eliza Hall Institute of Medical Research WEHI (), previously known as the Walter and Eliza Hall Institute of Medical Research, and as the Walter and Eliza Hall Institute, is Australia's oldest medical research institute. Sir Frank Macfarlane Burnet, who won the Nobel Prize in 1960 for ...

and the University of Sydney, he joined the faculty of the Stanford University Medical School and the

Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fi ...

in 1990. There he established the concept of multiple immune tolerance checkpoints, a framework now widely used in cancer treatment with "

checkpoint inhibitor Checkpoint inhibitor therapy is a form of cancer immunotherapy. The therapy targets immune checkpoints, key regulators of the immune system that when stimulated can dampen the immune response to an immunologic stimulus. Some cancers can protect ...

s", and revealed the function of key genes in these checkpoints. In 1997 Goodnow joined the faculty at the

Australian National University The Australian National University (ANU) is a public research university located in Canberra, the capital of Australia. Its main campus in Acton encompasses seven teaching and research colleges, in addition to several national academies an ...

as Professor and Founding Director of the Medical Genome Centre, leading its development into a major national research facility, the Australian Phenomics Facility. In 2015 he joined the

as Deputy Director to translate genomic DNA sequence analysis of the human immune system into understanding the cause of immune disorders and developing more effective, personalised treatments. During this period Goodnow oversaw the development of the Garvan-Weizmann Centre for Cellular Genomics in partnership with the

Weizmann Institute of Science The Weizmann Institute of Science ( he, מכון ויצמן למדע ''Machon Vaitzman LeMada'') is a public research university in Rehovot, Israel, established in 1934, 14 years before the State of Israel. It differs from other Israeli unive ...

in Israel, the only multidisciplinary centre of its kind in the southern hemisphere as well as playing a key role in the development of the Clinical Immunogenomics Research Consortium Australia (CIRCA). In May 2018, Goodnow was named Executive Director of the Garvan Institute.

Academic History

1979-84: Training in

Veterinary Medicine Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutri ...

and Surgery, Faculty of

Veterinary Science Veterinary medicine is the branch of medicine that deals with the prevention, management, diagnosis, and treatment of disease, disorder, and injury in animals. Along with this, it deals with animal rearing, husbandry, breeding, research on nutri ...

1983: B.Sc.Vet research, "Cellular and Molecular Studies of Kappa Myeloma

Antigen In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune respon ...

", Clinical Immunology Research Centre, University of Sydney, with Dr. R.L. Raison 1984: Graduated, University of Sydney, B.V.Sc. Hons I, and B.Sc.(Vet) Hons I and University Medal 1985: Visiting Student and Research Assistant in the laboratory of Dr. Mark M. Davis, Dept. of Medical

Microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, ...

Medical School 1985:

National Health and Medical Research Council The National Health and Medical Research Council (NHMRC) is the main statutory authority of the Australian Government responsible for medical research. It was the eighth largest research funding body in the world in 2016, and NHMRC-funded rese ...

Biomedical Scholar, Ph.D. research, "A transgenic

mouse A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus' ...

model for self-tolerance in B

lymphocytes A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. Lymphocytes include natural killer cells (which function in cell-mediated, cytotoxic innate immunity), T cells (for cell-mediated, cytotoxic ada ...

Walter and Eliza Hall Institute WEHI (), previously known as the Walter and Eliza Hall Institute of Medical Research, and as the Walter and Eliza Hall Institute, is Australia's oldest medical research institute. Sir Frank Macfarlane Burnet, who won the Nobel Prize in 1960 for ...

, with Professor Gustav JV Nossal 1986-89: NHMRC Biomedical Scholar, Ph.D. research, "A transgenic mouse model for self-tolerance in

B lymphocytes B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted or ...

", Clinical Immunology Research Centre,

, with Associate Professor Ronald J. Trent and Professor Antony Basten 1989-90: Medical Foundation Postdoctoral Fellow, Clinical Immunology Research Centre, University of Sydney, with Professor Antony Basten 1990-97: Assistant Investigator,

& Assistant Professor of Microbiology and Immunology,

Stanford University Medical School Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California. It traces its roots to the Medical Department of the University of the Pacific, founded in San Francisco in 1858. Th ...

1992-95:

Searle Scholar The Searle Scholars Program is a career development award made annually to the 15 young US professionals in biomedical research and chemistry considered most promising. The award was established in 1980 by a donation from the Searle family, and is ...

1997: Professor, Director of Medical Genome Centre, Australian Cancer Research Foundation Genetics Laboratory, The John Curtin School of Medical Research,

The Australian National University The Australian National University (ANU) is a public research university located in Canberra, the capital of Australia. Its main campus in Acton encompasses seven teaching and research colleges, in addition to several national academies and ...

2007-2014: Professor and Head of the Division of Genetics and Immunology, The John Curtin School of Medical Research,

2014–Present: Conjoint Professor, St Vincent's Clinical School, Faculty of Medicine,

Industry

Goodnow has served: * On the scientific advisory board of Illumina, a genetic analysis technology company; and * As founder and chief scientific officer for Phenomix Corp, a private biotechnology company.

Honours

* 1979: John Gurner and Frederick Ebsworth Prize for Biology,

* 1984: Honours Class I with B.V.Sc. degree; Honours Class I and University Medal with B.Sc.(Vet) degree * 1986:

Biomedical Research Scholarship * 1989: Medical Foundation Postdoctoral Fellowship * 1992-95:

* 1998:

American Association of Immunologists The American Association of Immunologists (AAI) is an international scientific society dedicated to furthering the study of immunology. AAI provides its members with a variety of platforms in which to exchange ideas and present the latest immunolo ...

/Pharmingen Investigator Award * 2001: Centenary Medal for services to Australian society and science in systems and control theory * 2001:

Australian Academy of Science The Australian Academy of Science was founded in 1954 by a group of distinguished Australians, including Australian Fellows of the Royal Society of London. The first president was Sir Mark Oliphant. The academy is modelled after the Royal Soc ...

Gottschalk Medal The Gottschalk Medal is awarded every year by the Australian Academy of Science to recognize outstanding research by Australian scientists under 40 years of age for research in the medical sciences conducted mainly in Australia. This medal commemor ...

* 2002: Elected a

Fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...

of the

* 2005: Australian Health Ministers Award for Excellence in Health and Medical Research * 2006:

Australian Research Council The Australian Research Council (ARC) is the primary non-medical research funding agency of the Australian Government, distributing more than in grants each year. The Council was established by the ''Australian Research Council Act 2001'', ...

Federation

* 2006:

Distinguished Lecturer * 2007: Ramaciotti Biomedical Research Award * 2009: Elected a

The Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, r ...

, the UK and

British Commonwealth The Commonwealth of Nations, simply referred to as the Commonwealth, is a political association of 56 member states, the vast majority of which are former territories of the British Empire. The chief institutions of the organisation are the Co ...

academy of science (confirmed 2009-05-15ANU immunology pioneer elected to The Royal Society

, 2009-05-15, accessed 2009-05-20) * 2010: Australasian Society for Immunology Burnet Orator * 2010:

of Australia

* 2010: Ramaciotti Medal for Excellence in Biomedical Research * 2012: Glaxo-Smith-Kline Award for Research Excellence * 2013: Elected Member of the US

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nat ...

* 2015-2016: President of the Australasian Society for Immunology

Other interests

Goodnow is well known for leading a 1980 expedition to Indonesia's remote

Mentawai Islands Mentawai may refer to: * Mentawai Islands * Mentawai Strait * Mentawai people * Mentawai language The Mentawai language is an Austronesian language, spoken by the Mentawai people of the Mentawai Islands, West Sumatra, Indonesia. Dialects Ac ...

off the coast of

Sumatra Sumatra is one of the Sunda Islands of western Indonesia. It is the largest island that is fully within Indonesian territory, as well as the sixth-largest island in the world at 473,481 km2 (182,812 mi.2), not including adjacent i ...

, discovering the now-famous surf breaks and a wave that is today considered one of the world's best, Macaronis.

External

Biography - Australian National UniversityAustralian Phenomics Facility

References

{{DEFAULTSORT:Goodnow, Chris 1959 births Living people Fellows of the Royal Society Australian immunologists Australian medical researchers Australian National University faculty WEHI alumni Stanford University School of Medicine faculty Howard Hughes Medical Investigators Fellows of the Australian Academy of Science Garvan Institute of Medical Research alumni