Carlos J. Finlay
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Carlos Juan Finlay (December 3, 1833 – August 20, 1915) was a Cuban epidemiologist recognized as a pioneer in the research of
yellow fever Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. ...
, determining that it was transmitted through mosquitoes ''
Aedes aegypti ''Aedes aegypti'', the yellow fever mosquito, is a mosquito that can spread dengue fever, chikungunya, Zika fever, Mayaro and yellow fever viruses, and other disease agents. The mosquito can be recognized by black and white markings on its le ...
''.


Biography


Early life and education

Finlay was born Juan Carlos Finlay y de Barrés in Puerto Príncipe (now Camagüey), Cuba to Scottish-born Dr. Edward (Eduardo) Finlay and French-born Elisa (Isabel) de Barrés. At that time Cuba was part of the Kingdom of Spain. He reversed the order of his given names to "Carlos Juan" later in his life. His father was a physician who had fought alongside Simón Bolívar, and his family owned a coffee plantation in Alquízar. He attended school in France in 1844, but was forced to return to Cuba after two years because he contracted
chorea Chorea (or choreia, occasionally) is an abnormal involuntary movement disorder, one of a group of neurological disorders called dyskinesias. The term ''chorea'' is derived from the grc, χορεία ("dance"; see choreia), as the quick movem ...


After recovering, he returned to Europe in 1848, but became stuck in England for another two years due to political turmoil, and after arriving in France to continue his education, he contracted
typhoid fever Typhoid fever, also known as typhoid, is a disease caused by '' Salmonella'' serotype Typhi bacteria. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over several ...
and again returned to Cuba. Because the University of Havana would not recognize his European academic credits, he enrolled at
Jefferson Medical College Thomas Jefferson University is a private research university in Philadelphia, Pennsylvania. Established in its earliest form in 1824, the university officially combined with Philadelphia University in 2017. To signify its heritage, the unive ...
in
Philadelphia, Pennsylvania Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...
, which did not require prerequisites. Here Finlay met John Kearsley Mitchell, a proponent of the
germ theory of disease The germ theory of disease is the currently accepted scientific theory for many diseases. It states that microorganisms known as pathogens or "germs" can lead to disease. These small organisms, too small to be seen without magnification, invade ...
, and his son Silas Weir Mitchell, who supervised his studies. He graduated from Jefferson Medical College in 1855. He then returned to
Havana Havana (; Spanish: ''La Habana'' ) is the capital and largest city of Cuba. The heart of the La Habana Province, Havana is the country's main port and commercial center.
and set up an ophthalmology practice in 1857, and then studied in
Paris Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), ma ...
in 1860–61. In October 1865 he married Adela Shine, a native of the
Island of Trinidad Trinidad is the larger and more populous of the two major islands of Trinidad and Tobago. The island lies off the northeastern coast of Venezuela and sits on the continental shelf of South America. It is often referred to as the southernmo ...
. They had three sons, Charles, George and Frank Finlay.


Professional career

Finlay's work, carried out during the 1870s, finally came to prominence in 1900. He was the first to theorize, in 1881, that a mosquito was a carrier, now known as a disease
vector Vector most often refers to: *Euclidean vector, a quantity with a magnitude and a direction *Vector (epidemiology), an agent that carries and transmits an infectious pathogen into another living organism Vector may also refer to: Mathematic ...
, of the organism causing
yellow fever Yellow fever is a viral disease of typically short duration. In most cases, symptoms include fever, chills, loss of appetite, nausea, muscle pains – particularly in the back – and headaches. Symptoms typically improve within five days. ...
: a mosquito that bites a victim of the disease could subsequently bite and thereby infect a healthy person. He presented this theory at the 1881 International Sanitary Conference, where it was well received. A year later Finlay identified a mosquito of the
genus Genus ( plural genera ) is a taxonomic rank used in the biological classification of living and fossil organisms as well as viruses. In the hierarchy of biological classification, genus comes above species and below family. In binomial nom ...
''
Aedes ''Aedes'' is a genus of mosquitoes originally found in tropical and subtropical zones, but now found on all continents except perhaps Antarctica. Some species have been spread by human activity: '' Aedes albopictus'', a particularly invasive sp ...
'' as the organism transmitting yellow fever. His theory was followed by the recommendation to control the mosquito population as a way to control the spread of the diseas

His hypothesis and exhaustive proofs were confirmed nearly twenty years later by the Walter Reed, Walter Reed Commission of 1900. Finlay went on to become the chief health officer of Cuba from 1902 to 1909. Although Reed received much of the credit in history books for "beating" yellow fever, Reed himself credited Finlay with the discovery of the yellow fever vector, and thus how it might be controlled. Reed often cited Finlay's papers in his own articles and gave him credit for the discovery in his personal correspondence.Pierce J.R., J, Writer. 2005. Yellow Jack: How Yellow Fever Ravaged America and Walter Reed Discovered its Deadly Secrets. John Wiley and Sons. In the words of General
Leonard Wood Leonard Wood (October 9, 1860 – August 7, 1927) was a United States Army major general, physician, and public official. He served as the Chief of Staff of the United States Army, Military Governor of Cuba, and Governor-General of the Philipp ...
, a physician and
U.S. The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
military governor of Cuba in 1900: "The confirmation of Dr. Finlay's doctrine is the greatest step forward made in medical science since Jenner's discovery of the vaccination or_smallpox.html" ;"title="smallpox.html" ;"title="or smallpox">or smallpox">smallpox.html" ;"title="or smallpox">or smallpox" This discovery helped William C. Gorgas reduce the incidence and prevalence of mosquito-borne diseases in Panama during the American campaign, from 1903 onwards, to construct the Panama Canal. Prior to this, about 10% of the workforce had died each year from
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
and yellow fever. Finlay was a member of Havana's Royal Academy of Medical, Physical and Natural Sciences. He was fluent in French,
German German(s) may refer to: * Germany (of or related to) ** Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Ge ...
,
Spanish Spanish might refer to: * Items from or related to Spain: **Spaniards are a nation and ethnic group indigenous to Spain **Spanish language, spoken in Spain and many Latin American countries **Spanish cuisine Other places * Spanish, Ontario, Can ...
, and
English English usually refers to: * English language * English people English may also refer to: Peoples, culture, and language * ''English'', an adjective for something of, from, or related to England ** English national ide ...
and could read
Latin Latin (, or , ) is a classical language belonging to the Italic branch of the Indo-European languages. Latin was originally a dialect spoken in the lower Tiber area (then known as Latium) around present-day Rome, but through the power of the ...
. His interests were widespread and he wrote articles on subjects as varied as
leprosy Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damag ...
, cholera,
gravity In physics, gravity () is a fundamental interaction which causes mutual attraction between all things with mass or energy. Gravity is, by far, the weakest of the four fundamental interactions, approximately 1038 times weaker than the stro ...
, and
plant diseases Plant pathology (also phytopathology) is the scientific study of diseases in plants caused by pathogens (infectious organisms) and environmental conditions (physiological factors). Organisms that cause infectious disease include fungi, oomy ...
. His main interest, however, was yellow fever, and he was the author of 40 articles on this disease. His theory that an intermediary host was responsible for the spread of the disease was treated with ridicule for years. A humane man, he often took on patients who could not afford medical care. As a result of his work, Finlay was nominated seven times for the
Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...
, although he was never awarded the prize.Crosby, M.C. 2006. The American Plague: The Untold Story of Yellow Fever, The Epidemic That Shaped Our History. Berkley Books. He received the National Order of the
Legion of Honour The National Order of the Legion of Honour (french: Ordre national de la Légion d'honneur), formerly the Royal Order of the Legion of Honour ('), is the highest French order of merit, both military and civil. Established in 1802 by Napoleon ...
of France in 1908. Finlay died from a stroke, caused by severe brain seizures, at his house in Havana on August 20, 1915.


Legacy

In 1928, President Gerardo Machado established the National Order of Merit Carlos J. Finlay, rewarding contributions to healthcare and medicine. It is the highest scientific decoration awarded by the Cuban Council of State. The order was discontinued between 1959 and 1981. On Cuba Street in downtown
Old Havana Old Havana ( es, link=no, La Habana Vieja) is the city-center (downtown) and one of the 15 municipalities (or boroughs) forming Havana, Cuba. It has the second highest population density in the city and contains the core of the original city of ...
, the Revolutionary Government in 1962 founded a medical history museum in honor of Carlos J. Finlay. On the wall of the Finlay Medical History Museum in Havana, the inscription states, "History Museum of the Medical Sciences ' Carlos J. Finlay', created by the Revolutionary Government in eternal homage to the men who contributed to the advance of the sciences in Cuba. National Commission of the Academy of Sciences of the Republic of Cuba. Havana, 13 June 1962." In the municipality of
Marianao Marianao is one of the 15 municipalities or boroughs (''municipios'' in Spanish) in the city of Havana, Cuba. It lies 6 miles southwest of the original city of Havana, with which it is connected by the Marianao railway. In 1989 the municipality had ...
, now within the city of
Havana Havana (; Spanish: ''La Habana'' ) is the capital and largest city of Cuba. The heart of the La Habana Province, Havana is the country's main port and commercial center.
, there is a monument in the shape of a syringe, honoring Finlay and usually referred to as ''El Obelisco'' (''The Obelisk''). Finlay was also commemorated on a 1981 Cuban stamp. A statue commemorating Finlay is located on the bayfront in
Panama City Panama City ( es, Ciudad de Panamá, links=no; ), also known as Panama (or Panamá in Spanish), is the capital and largest city of Panama. It has an urban population of 880,691, with over 1.5 million in its metropolitan area. The city is locat ...
, near the canal he helped make possible. The
UNESCO The United Nations Educational, Scientific and Cultural Organization is a specialized agency of the United Nations (UN) aimed at promoting world peace and security through international cooperation in education, arts, sciences and culture. It ...
Carlos J. Finlay Prize for Microbiology The Carlos J. Finlay Prize is a biennial scientific prize sponsored by the Government of Cuba and awarded since 1980 by the United Nations Educational, Scientific and Cultural Organization (UNESCO) to people or organizations for their outstanding ...
is named in his honor. Finlay was honoured with a
Google Doodle A Google Doodle is a special, temporary alteration of the logo on Google's homepages intended to commemorate holidays, events, achievements, and notable historical figures. The first Google Doodle honored the 1998 edition of the long-running an ...
on December 3, 2013, on the 180th anniversary of his birth. Carlos J. Finlay Military Hospital is named after him. The Finlay Institute for Vaccines (Instituto Finlay de Vacunas, in Spanish), created in 1991, is named after him.


See also

* Healthcare in Cuba * Health measures during the construction of the Panama Canal


Footnotes


References

* * bkfa * * * * * Pierce J.R., J, Writer. 2005. Yellow Jack: How Yellow Fever Ravaged America and Walter Reed Discovered its Deadly Secrets. John Wiley and Sons. * Crosby, M.C. 2006. The American Plague: The Untold Story of Yellow Fever, The Epidemic That Shaped Our History. Berkley Books. * Jefferson Medical College hosted an international symposium celebrating accomplishments of Dr. Carlos Finla
Yellow Fever, A Symposium in Commemoration of Carlos Juan Finlay
1955.


External links


Carlos Juan Finlay article from Encyclopedia of World Biography

Carlos J. Finlay article from Encyclopaedia Britannica

Carlos Juan Finlay article from The American Academy of Ophthalmology
{{DEFAULTSORT:Finlay, Carlos Yellow fever 1833 births 1915 deaths Walter Reed Cuban scientists Cuban epidemiologists Cuban people of Scottish descent Cuban people of French descent People from Camagüey Jefferson Medical College alumni Cuban ophthalmologists