CP-615,003 is a drug which acts as a subtype-selective

partial agonist In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist. They may also be considered ligands which display both agonistic and antagonis ...

at GABA_A receptors, and was developed by

Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...

as a potential

anxiolytic An anxiolytic (; also antipanic or antianxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxiet ...

; however, poor blood–brain barrier penetration make it primarily useful as a research ligand.

References

Anxiolytics Drugs developed by Pfizer GABAA receptor positive allosteric modulators Peripherally selective drugs Fluoroarenes Ethanolamines Carboxamides Cyclohexyl compounds Pyrroles {{Anxiolytic-stub