Brief psychotic disorder
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Brief psychotic disorder ⁠— according to the classifications of mental disorders
DSM-IV-TR The ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM; latest edition: DSM-5-TR, published in March 2022) is a publication by the American Psychiatric Association (APA) for the classification of mental disorders using a common langua ...
and
DSM-5 The ''Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition'' (DSM-5), is the 2013 update to the '' Diagnostic and Statistical Manual of Mental Disorders'', the taxonomic and diagnostic tool published by the American Psychiatri ...
⁠— is a psychotic condition involving the sudden onset of at least one psychotic symptom (such as disorganized thought/speech, delusions, hallucinations, or grossly
disorganized Chaos theory is an interdisciplinary area of scientific study and branch of mathematics focused on underlying patterns and deterministic laws of dynamical systems that are highly sensitive to initial conditions, and were once thought to have ...
or catatonic behavior) lasting 1 day to 1 month, often accompanied by emotional turmoil. Remission of all symptoms is complete with patients returning to the previous level of functioning. It may follow a period of extreme stress including the loss of a loved one. Most patients with this condition under DSM-5 would be classified as having acute and transient psychotic disorders under ICD-10. Prior to
DSM-IV The ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM; latest edition: DSM-5-TR, published in March 2022) is a publication by the American Psychiatric Association (APA) for the classification of mental disorders using a common langu ...
, this condition was called "brief ''reactive'' psychosis." This condition may or may not be recurrent, and it should not be caused by another condition. The term bouffée délirante describes an acute non-affective and non-schizophrenic psychotic disorder, which is largely similar to DSM-III-R and DSM-IV brief psychotic and
schizophreniform disorder Schizophreniform disorder is a mental disorder diagnosed when symptoms of schizophrenia are present for a significant portion of time (at least a month), but signs of disturbance are not present for the full six months required for the diagnosis ...
s. __TOC__


Presentation

Brief psychotic disorder is characterized by a sudden onset of psychotic symptoms, which may include delusions, hallucinations, disorganized speech or behavior, or catatonic behavior. Symptoms generally last at least a day, but not more than a month, and there is an eventual return to full baseline functioning. Brief psychotic disorder may occur in response to a significant
stressor A stressor is a chemical or biological agent, environmental condition, external stimulus or an event seen as causing stress to an organism. Psychologically speaking, a stressor can be events or environments that individuals might consider demandin ...
in one's life, or in other situations where a stressor is not apparent, including in the weeks following birth. In diagnosis, a careful distinction is considered for culturally appropriate behaviors, such as religious beliefs and activities. It is believed to be connected to or synonymous with a variety of culture-specific phenomena such as latah,
koro Koro may refer to: Geography *Koro Island, a Fijian island * Koro Sea, in the Pacific Ocean * Koro, Ivory Coast *Koro, Mali * Koro, Wisconsin, United States, an unincorporated community Languages *Koro language (India), an endangered language spo ...
, and amok.


Classification

There are three forms of brief psychotic disorder: * Brief psychotic disorder ''with a marked stressor'' (a.k.a. brief reactive psychosis): if brief psychotic disorder symptoms occur in following personal events (single or multiple) that would be expected to cause significant stress to an average individual. * Brief psychotic disorder ''without a marked stressor'': if brief psychotic disorder symptoms do not occur in following personal events (single or multiple) that would be expected to cause significant stress to an average individual. * Brief psychotic disorder ''with postpartum onset'': if onset of brief psychotic disorder symptoms is during pregnancy or within 4 weeks after birth.


Brief psychotic disorder with a marked stressor (brief reactive psychosis)

Brief reactive psychosis (designated since the DSM IV-TR as "brief psychotic disorder with marked stressor(s), BRP"), is the psychiatric term for
psychosis Psychosis is a condition of the mind that results in difficulties determining what is real and what is not real. Symptoms may include delusions and hallucinations, among other features. Additional symptoms are incoherent speech and behavior ...
which can be triggered by an extremely stressful event in the life of an individual and eventually yielding to a return to normal functioning. Brief reactive psychosis generally follows a recognisably traumatic life event like divorce or homelessness, but may be triggered by any subjective experience which appears catastrophic to the person affected. Among such stressors are the death of a loved one, professional loss such as unexpectedly losing one's job or otherwise becoming unemployed, or serious adverse changes in the patient's personal life, such as the breakdown of their family through divorce, etc. It must be emphasised that this is by no means an exhaustive list of stressful life events, because the events which trigger brief reactive psychosis tend, due to the individualistic nature of human psychology, to be extremely personalized. BRP may be the first breakdown for someone with a chronic psychiatric disorder but only time will tell whether the disorder will be brief or lifelong, whether BRP or a chronic condition that is controlled well enough by medication that symptoms do not return. The condition usually resolves spontaneously within a time span of weeks to months, with the severity of the symptoms reducing continuously over the period in question. A primary goal of treatment is to prevent patients who are either suicidal or homicidal from harming themselves or others during the episode.


Cause/pathophysiology

The exact cause of brief psychotic disorder is not known. One theory suggests a genetic link, because the disorder is more common in people who have family members with mood disorders, such as depression or bipolar disorder. Another theory suggests that the disorder is caused by poor coping skills, as a defense against or escape from a particularly frightening or stressful situation. These factors may create a vulnerability to develop brief psychotic disorder. In most cases, the disorder is triggered by a major stress or traumatic event. In females, a low
estrogen Estrogen or oestrogen is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens that have estrogenic hormonal ac ...
state (which may occur premenstrual, postpartum, or perimenopausal) can trigger sudden, short-lived psychosis. The psychosis is often linked to an underlying bipolar or schizophrenic condition. Such psychosis (when diagnosed as such), is often considered "premenstrual exacerbation" or "menstrual psychosis", or postpartum psychosis. Childbirth may trigger the disorder in some women. Approximately 1 in 10,000 women experience brief psychotic disorder shortly after childbirth.


Diagnosis

The symptoms must not be caused by
schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social wit ...
,
schizoaffective disorder Schizoaffective disorder (SZA, SZD or SAD) is a mental disorder characterized by abnormal thought processes and an unstable mood. This diagnosis is made when the person has symptoms of both schizophrenia (usually psychosis) and a mood disorder: ...
,
delusional disorder Delusional disorder is a mental illness in which a person has delusions, but with no accompanying prominent hallucinations, thought disorder, mood disorder, or significant flattening of affect.American Psychiatric Association. (2013). ''Diagnostic ...
, or mania in
bipolar disorder Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that last from days to weeks each. If the elevated mood is severe or associated with ...
. They must also not be caused by a drug (such as
amphetamines Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with sub ...
) or medical condition (such as a
brain tumor A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and seconda ...
).


Differential diagnosis

There are general medical causes of brief psychosis that should be considered during evaluation, including
postnatal depression Postpartum depression (PPD), also called postnatal depression, is a type of mood disorder associated with childbirth, which can affect both sexes. Symptoms may include extreme sadness, low energy, anxiety, crying episodes, irritability, and chan ...
,
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
and AIDS,
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, syphilis, Alzheimer's disease,
Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
,
hypoglycaemia Hypoglycemia, also called low blood sugar, is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L). Whipple's triad is used to properly identify hypoglycemic episodes. It is defined as blood glucose bel ...
(an abnormally low level of glucose in the blood), lupus, multiple sclerosis,
brain tumor A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and seconda ...
, SARS-CoV-2 (COVID-19) infection and pediatric autoimmune neuropsychiatric disorders (PANS).


Epidemiology

The exact incidence and prevalence of brief psychotic disorder is not known, but it is generally considered uncommon. Internationally, it occurs twice as often in women than men, and even more often in women in the United States. It typically occurs in the late 30s and early 40s. Approximately 1 in 10,000 women experience brief psychotic disorder shortly after childbirth.


History

Otto Fenichel noted how such short psychotic breaks were more common in World War II than in World War I, in the wake of traumatic shocks: he considered in such cases that "enough preconscious attention remains to re-establish the contact with reality as soon as it becomes bearable again".


BPD in Film/TV/Media

BPD and its symptoms were featured in the
Kevin Spacey Kevin Spacey Fowler (born July 26, 1959) is an American actor. He began his career as a stage actor during the 1980s, obtaining supporting roles before gaining a leading man status in film and television. Spacey has received various accolade ...
and
Daniel Wu Daniel Ng Neh-Tsu (, born September 30, 1974) is an American actor, director and producer based in Hong Kong. He is known as a "flexible and distinctive" leading actor in the Chinese language film industry. Since his film debut in 1998, he has ...
-starring film '' Inseparable''. Daniel Wu's character developed BPD after a series of tragedies.


See also

* Bouffée délirante * Menstrual psychosis * Mental breakdown *
Schizophreniform disorder Schizophreniform disorder is a mental disorder diagnosed when symptoms of schizophrenia are present for a significant portion of time (at least a month), but signs of disturbance are not present for the full six months required for the diagnosis ...


References


Further reading

* * *


External links


Causes of Psychosis
{{Medical resources , ICD10 = {{ICD10, F, 23} Psychosis