Bone morphogenetic protein type I receptors are single pass, type I

transmembrane proteins A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the cell membrane. Many transmembrane proteins function as gateways to permit the transport of specific substances across the membrane. They frequentl ...

. They belong to a class of receptor serine/threonine kinases that bind members of the TGF beta superfamily of ligands-the Bone morphogenetic proteins. The three types of type I BMP receptors are

ACVR1 Activin A receptor, type I (ACVR1) is a protein which in humans is encoded by the ''ACVR1'' gene; also known as ALK-2 (activin receptor-like kinase-2). ACVR1 has been linked to the 2q23-24 region of the genome. This protein is important in the bo ...

BMPR1A The bone morphogenetic protein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the ''BMPR1A'' gene. BMPR1A has also been designated as CD292 (cluster of differentiation 292). Function The bone morphogenetic pr ...

and BMPR1B.

External links

* Receptors Transmembrane receptors S/T domain GS domain Bone morphogenetic protein EC 2.7.11 {{Transmembranereceptor-stub