Augustin Nicolas Gilbert (15 February 1858 – 4 March 1927) was a French physician. He was born in the town of

Buzancy, Ardennes Buzancy () is a commune in the Ardennes department and Grand Est region of north-eastern France. Population See also *Communes of the Ardennes department The following is a list of the 449 communes of the Ardennes department of France ...

, and died in Paris. Augustin Nicolas Gilbert b012532

He received his doctorate from the

University of Paris , image_name = Coat of arms of the University of Paris.svg , image_size = 150px , caption = Coat of Arms , latin_name = Universitas magistrorum et scholarium Parisiensis , motto = ''Hic et ubique terrarum'' (Latin) , mottoeng = Here and a ...

and became an interne at the

Hôtel-Dieu de Paris In French-speaking countries, a hôtel-Dieu ( en, hostel of God) was originally a hospital for the poor and needy, run by the Catholic Church. Nowadays these buildings or institutions have either kept their function as a hospital, the one in Paris b ...

. Later he was a professor of therapeutics (1902) and clinical medicine (1905) at Hôtel-Dieu. In 1907 he became a member of the ''

Académie de Médecine An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosop ...

''. He published many articles and books on a wide array of medical subjects. With

Jean Alfred Fournier Jean Alfred Fournier () (21 May 1832 – 25 December 1914) was a French dermatologist who specialized in the study of venereal disease. Biography As a young man he served as an interne at the Hôpital du Midi as an understudy to Philippe Rico ...

(1832-1914) he published ''Bibliothèque rouge de l'étudiant en médecine'', and with Paul Brouardel (1837-1906) and others, he published the multi-volume ''Traité de médecine et de Thérapeutique''. With

neurologist Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...

Maurice Villaret Maurice Villaret (7 September 1877 – 25 January 1946) was a French neurologist born in Paris. In 1906 he received his medical doctorate from the University of Paris. In 1919 he became ''médecin des hôpitaux'' in Paris, and subsequently served ...

(1877–1946), he conducted extensive research of

portal hypertension Portal hypertension is abnormally increased portal venous pressure – blood pressure in the portal vein and its branches, that drain from most of the intestine to the liver. Portal hypertension is defined as a hepatic venous pressure gradient ...

. Gilbert described a hereditary cause of increased

bilirubin Bilirubin (BR) ( Latin for "red bile") is a red-orange compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the body's clearance of waste products that arise from t ...

; today this disorder is known as

Gilbert's syndrome Gilbert syndrome (GS) is a syndrome in which the liver of affected individuals processes bilirubin more slowly than the majority. Many people never have symptoms. Occasionally jaundice (a slight yellowish color of the skin or whites of the eyes) ...

and is believed to be caused by a deficiency of the

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...

glucuronosyltransferase Uridine 5'-diphospho-glucuronosyltransferase ( UDP-glucuronosyltransferase, UGT) is a microsomal glycosyltransferase () that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is ...

Works

* ''Formulaire : ncien Formulaire de Dujardin-Beaumetz' . Doin, Paris 23e Ed. 191
Digital edition
by the

University and State Library Düsseldorf The University and State Library Düsseldorf (german: Universitäts- und Landesbibliothek Düsseldorf, abbreviated ULB Düsseldorf) is a central service institution of Heinrich Heine University. Along with Bonn and Münster, it is also one of t ...

References

{{DEFAULTSORT:Gilbert, Augustin Nicolas 20th-century French physicians 1858 births 1927 deaths People from Ardennes (department) 19th-century French physicians