AryoGen Pharmed ( fa, آریوژن فارمد) is an Iranian biopharmaceutical company specializing in manufacturing Therapeutic Monoclonal antibodies and some other

recombinant proteins Recombinant DNA (rDNA) molecules are DNA molecules formed by laboratory methods of genetic recombination (such as molecular cloning) that bring together genetic material from multiple sources, creating sequences that would not otherwise be fou ...

History

AryoGen is a biopharmaceutical company created on the mandate of Iranian executive branch. It was created by a group of scientific experts spun off a

Biopharmaceutical A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, t ...

company, which formed a new entity named AryoGen Pharmed which started its production in 2011. It was deemed an issue of national interest due to the importance of the target products on Iran's community health care system, as well as its impact in the region and globally. AryoGen is the world's first company to produce biosimilar Blood

Coagulation Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanis ...

Factor VII, which required a 50 million Euro investment. Also AryoGen has established a monoclonal antibody production line, making it one of only 10 manufacturers in the world. AryoGen changed its name to AryoGen Pharmed in 2016. AryoGen Pharmed (AryoGen) has received a Good Manufacturing Practice (GMP) certificate from th
European Medicines Agency (EMA)
becoming one of the first

monoclonal antibody A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies ...

(mAb) manufacturers in the Middle East and North Africa (MENA) region to be certified. inside Aryogen

Products

AryoGen's products include: * Blood

factor VII with the name of

AryoSeven Recombinant factor VIIa also known as eptacog alfa (INN), and sold under the brand name NovoSeven among others, is a form of blood factor VII that has been manufactured via recombinant technology. It is administered intravenously (IV). Medical ...

which is a biosimilar form of Novoseven with multi billion dollars world market and is used for hemophilia patients and other conditions * Altebrel with the generic name of

Etanercept Etanercept, sold under the brand name Enbrel among others, is a biologic medical product that is used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. It ...

and original trade name of Enbrel which for some years was the no. one in the biopharmaceutical market and is used for treatment of autoimmune diseases * Zytux with the generic name of

Rituximab Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in non-geriatric pa ...

and original trade name of

Rituxan Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in non-geriatric pa ...

which is an anticancer biomedicine, * َAryoTrust with the generic name of

trastuzumab Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically used for cancer that is HER2 receptor positive. It may be used by itself or together wi ...

and original name of

Herceptin Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. It is specifically used for cancer that is HER2 receptor positive. It may be used by itself or together wi ...

which is a revolutionary drug in treatment of breast cancer * Stivant with the generic name of bevacizumab and original trade name of Avestin and is used for treatment of some sort of cancer.

is now approved by Iranian food and drug organisation and from August 2012 is in the market and other biomedicines are closing to the market. {{wide image, AryoGen Biopharma Complex panorama.jpg, 1100px, alt= 22000 sqm AryoGen Biopharma complex in a panorama photo, align-cap=center, AryoGen Pharmed Complex.

References

External links

AryoGen - Home

Hemophilia

List of biopharmaceutical companies

Related Clinical trials
Biopharmaceutical companies Pharmaceutical companies of Iran Pharmaceutical companies established in 2009

History

Products

See also

References

External links