Albert Ludwig Sigesmund Neisser (22 January 1855, Schweidnitz – 30 July 1916, Breslau) was a German

physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...

who discovered the causative agent (

pathogen In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ ...

) of

gonorrhea Gonorrhea, colloquially known as the clap, is a sexually transmitted infection (STI) caused by the bacterium '' Neisseria gonorrhoeae''. Infection may involve the genitals, mouth, or rectum. Infected men may experience pain or burning with ...

, a strain of

bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...

that was named in his honour (''Neisseria gonorrhoeae'').

Life and career

Neisser was born in the

Silesia Silesia (, also , ) is a historical region of Central Europe that lies mostly within Poland, with small parts in the Czech Republic and Germany. Its area is approximately , and the population is estimated at around 8,000,000. Silesia is split ...

n town of Schweidnitz (now Świdnica, in Poland), the son of a well-known

Jewish Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The ...

physician, Moritz Neisser. After he completed the elementary school in Münsterberg, Neisser enrolled in the St. Maria Magdalena School in Breslau (now Wrocław, in Poland). In this school, he was a contemporary of another great name in the history of medicine,

Paul Ehrlich Paul Ehrlich (; 14 March 1854 – 20 August 1915) was a Nobel Prize-winning German physician and scientist who worked in the fields of hematology, immunology, and antimicrobial chemotherapy. Among his foremost achievements were finding a cure ...

. He obtained the

Abitur ''Abitur'' (), often shortened colloquially to ''Abi'', is a qualification granted at the end of secondary education in Germany. It is conferred on students who pass their final exams at the end of ISCED 3, usually after twelve or thirteen year ...

in 1872. Neisser began to study

medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...

at the

University of Breslau A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, th ...

, but later moved to

Erlangen Erlangen (; East Franconian German, East Franconian: ''Erlang'', Bavarian language, Bavarian: ''Erlanga'') is a Middle Franconian city in Bavaria, Germany. It is the seat of the administrative district Erlangen-Höchstadt (former administrative d ...

, completing his studies in 1877. Initially Neisser wanted to be an internist, but did not find a suitable place. He found work, however as an assistant of the dermatologist Oskar Simon (1845–1892), concentrating on

sexually transmitted diseases Sexually transmitted infections (STIs), also referred to as sexually transmitted diseases (STDs) and the older term venereal diseases, are infections that are spread by sexual activity, especially vaginal intercourse, anal sex, and oral sex ...

and

leprosy Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damag ...

. During the following two years he studied and obtained experimental evidence about the pathogen for gonorrhea, ''

Neisseria gonorrhoeae ''Neisseria gonorrhoeae'', also known as ''gonococcus'' (singular), or ''gonococci'' (plural), is a species of Gram-negative diplococci bacteria isolated by Albert Ludwig Sigesmund Neisser, Albert Neisser in 1879. It causes the sexually transmit ...

''. Neisser was also the co-discoverer of the causative agent of leprosy. In 1879 the Norwegian physician

Gerhard Armauer Hansen Gerhard Henrik Armauer Hansen () (29 July 1841 – 12 February 1912) was a Norwegian physician, remembered for his identification of the bacterium ''Mycobacterium leprae'' in 1873 as the causative agent of leprosy. His distinguished work was ...

gave to young Neisser (who had visited him in Norway to examine some 100 leprosy patients) some tissue samples of his patients. Neisser successfully stained the bacteria and announced his findings in 1880, claiming to have discovered the pathogenesis of leprosy. There was some conflict between Neisser and Hansen, because Hansen had failed to culture the organism and demonstrate unequivocally its link to leprosy, although he had observed the bacterium since 1872. In 1882 Neisser was appointed

professor extraordinarius Academic ranks in Germany are the titles, relative importance and power of professors, researchers, and administrative personnel held in academia. Overview Appointment grades * (Pay grade: ''W3'' or ''W2'') * (''W3'') * (''W2'') * (''W2'', ...

by the University at the age of 29, and worked as a

dermatologist Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical ...

in the university hospital of Breslau. Later he was promoted to the head of the hospital. In the following year he married Toni Neisser, née Kauffmann. In 1898 Albert Neisser published clinical trials on serum therapy in patients with syphilis. He injected cell free serum from patients with syphilis into patients who were admitted for other medical conditions. Most of these patients were prostitutes, who were neither informed about the experiment nor asked for their consent. When some of them contracted syphilis Neisser argued that the women did not contract syphilis as a result of his serum injections but contracted the disease because they worked as prostitutes. In 1905 and 1906 Neisser travelled to

Java Java (; id, Jawa, ; jv, ꦗꦮ; su, ) is one of the Greater Sunda Islands in Indonesia. It is bordered by the Indian Ocean to the south and the Java Sea to the north. With a population of 151.6 million people, Java is the world's List ...

, in order to study the possible transmission of

syphilis Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, an ...

from

apes Apes (collectively Hominoidea ) are a clade of Old World simians native to sub-Saharan Africa and Southeast Asia (though they were more widespread in Africa, most of Asia, and as well as Europe in prehistory), which together with its sister g ...

to humans. He later cooperated with

August Paul von Wassermann August Paul von Wassermann (21 February 1866 – 16 March 1925) was a German bacteriologist and hygienist. Born in Bamberg, with Jewish origins, he studied at several universities throughout Germany, receiving his medical doctorate in 1888 from ...

(1866–1925) to develop the famous diagnostic test for detecting ''

Treponema pallidum ''Treponema pallidum'', formerly known as ''Spirochaeta pallida'', is a spirochaete bacterium with various subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only among humans. It is ...

'' infections, and also in the testing of the first chemotherapeutic agent for syphilis,

Salvarsan Arsphenamine, also known as Salvarsan or compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the fi ...

, which was discovered by his former school fellow

in 1910. In 1907, Neisser was promoted to

professor ordinarius Academic ranks in Germany are the titles, relative importance and power of professors, researchers, and administrative personnel held in academia. Overview Appointment grades * (Pay grade: ''W3'' or ''W2'') * (''W3'') * (''W2'') * (''W2'', ...

of dermatology and sexually transmitted diseases at Breslau. As a scientific leader, Neisser was also very active. In the field of

public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...

, he promoted vigorously preventive and educational measures to the public, and the better sanitary control of

prostitutes Prostitution is the business or practice of engaging in sexual activity in exchange for payment. The definition of "sexual activity" varies, and is often defined as an activity requiring physical contact (e.g., sexual intercourse, non-penet ...

, in order to combat venereal diseases. He was one of the founder of the ''Deutsche Gesellschaft zur Bekämpfung der Geschlechtskrankheiten'' (German Society for the Fight Against Venereal Diseases) in 1902, and of the Deutsche Dermatologische Gesellschaft (German Dermatological Society) in 1888. Neisser died of

sepsis Sepsis, formerly known as septicemia (septicaemia in British English) or blood poisoning, is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. This initial stage is follo ...

on 30 July 1916, at the age of 61 years, in Breslau.

Albert Neisser Lectureship

The Albert Neisser Lectureship has been awarded since 2005 by the Department of Dermatology at the

University of Wrocław , ''Schlesische Friedrich-Wilhelms-Universität zu Breslau'' (before 1945) , free_label = Specialty programs , free = , colors = Blue , website uni.wroc.pl The University of Wrocław ( pl, Uniwersytet Wrocławski, U ...

to dermatologists who have made significant clinical and research contributions to the field. Past awardees include:

References

External links

Albert Neisser
WhoNamedIt. {{DEFAULTSORT:Neisser, Albert German microbiologists German pathologists 1855 births 1916 deaths German leprologists German venereologists Jewish dermatologists German people of Jewish descent Silesian Jews People from Świdnica People from the Province of Silesia Deaths from sepsis Infectious disease deaths in Germany 19th-century biologists 19th-century German physicians 19th-century German scientists