Adiponectin receptor
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The adiponectin receptors (AdipoRs) include the following two
receptor Receptor may refer to: *Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a n ...
s, which are bound and activated by
adiponectin Adiponectin (also referred to as GBP-28, apM1, AdipoQ and Acrp30) is a protein hormone and adipokine, which is involved in regulating glucose levels as well as fatty acid breakdown. In humans it is encoded by the ''ADIPOQ'' gene and it is produ ...
: *
Adiponectin receptor 1 Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ''ADIPOR1'' gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR1. Structure Similar to G protein-coupled receptors (GP ...
(AdipoR1, PAQR1) * Adiponectin receptor 2 (AdipoR2, PAQR2) They are members of the
progestin and adipoQ receptor The progestin and adipoQ receptor (PAQR) family is a group of receptors related to but distinct from the G protein-coupled receptor family, which have the similar seven transmembrane structure, but the N-terminal is located on the inner side of ...
(PAQR) family. In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoR1 and AdipoR2 identification data, as accused by an anonymous person/group called
Ordinary_researchers In 2010s, a series of separate allegations of scientific misconducts were raised involving several scientific papers from various Japanese universities. Shigeaki Kato In February 1996, Shigeaki Kato, who had studied in the laboratory of Pierre Ch ...
.University of Tokyo to investigate data manipulation charges against six prominent research groups
ScienceInsider, Dennis Normile, Sep 20, 2016


References

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