ATC code L03
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L03A Immunostimulants


L03AA

Colony stimulating factor Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiat ...
s

:L03AA02
Filgrastim Filgrastim, sold under the brand name Neupogen among others, is a medication used to treat low neutrophil count. Low neutrophil counts may occur with HIV/AIDS, following chemotherapy or radiation poisoning, or be of an unknown cause. It may ...
:L03AA03
Molgramostim Molgramostim is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator Immunostimulants, also known as immunostimulators, are substances (drugs and nutrients) that stimulate the immune system by ind ...
:L03AA09
Sargramostim Sargramostim (tradename Leukine) is a recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) that functions as an immunostimulator. Medical uses Sargramostim is primarily used for myeloid reconstitution after autologous or allogene ...
:L03AA10
Lenograstim Lenograstim is a recombinant granulocyte colony-stimulating factor Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocy ...
:L03AA12
Ancestim Ancestim is a recombinant methionyl human stem cell factor, branded by Amgen as StemGen. It was developed by Amgen and sold to Biovitrium, now Swedish Orphan Biovitrum, in December, 2008.Amgen press officeBiovitrum Closes Product Acquisition Dea ...
:L03AA13
Pegfilgrastim Pegfilgrastim, sold under the brand name Neulasta among others, is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. It serves to stimulate the production of white blood cells ( neutrophils ...
:L03AA14 Lipegfilgrastim :L03AA15 Balugrastim :L03AA16 Empegfilgrastim :L03AA17 Pegteograstim :L03AA18 Efbemalenograstim alfa :QL03AA90 Pegbovigrastim


L03AB Interferons

:L03AB01
Interferon alfa Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa con ...
natural :L03AB02 Interferon beta natural :L03AB03
Interferon gamma Interferon gamma (IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheeloc ...
:L03AB04 Interferon alfa-2a :L03AB05
Interferon alfa-2b Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and produced recombinantly in '' E. coli'' in the laboratory of Charles Weissmann at the Univers ...
:L03AB06 Interferon alfa-n1 :L03AB07
Interferon beta-1a Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian cells, while interferon beta-1b is produced in modified '' E. coli''. Some research indic ...
:L03AB08 Interferon beta-1b :L03AB09 Interferon alfacon-1 :L03AB10
Peginterferon alfa-2b Pegylated interferon alfa-2b is a drug used to treat melanoma, as an adjuvant therapy to surgery. Also used to treat hepatitis C (typically, in combination with ribavarin), it is no longer recommended due to poor efficacy and adverse side-effects ...
:L03AB11
Peginterferon alfa-2a Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B. For hepatitis C it is typically used together with ribavirin and cure rates are between 24 and 92%. For hepatit ...
:L03AB12 Albinterferon alfa-2b :L03AB13 Peginterferon beta-1a :L03AB14 Cepeginterferon alfa-2b :L03AB15 Ropeginterferon alfa-2b :L03AB16 Peginterferon alfacon-2 :L03AB60 Peginterferon alfa-2b, combinations :L03AB61 Peginterferon alfa-2a, combinations :QL03AB90 Interferom omega, feline origin


L03AC

Interleukin Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related ...
s

:L03AC01 Aldesleukin :L03AC02 Oprelvekin


L03AX Other immunostimulants

:L03AX01
Lentinan Lentinan is a polysaccharide isolated from the fruit body of shiitake mushroom (''Lentinula edodes'' mycelium). Chemistry Lentinan is a β-1,3 beta-glucan with β-1,6 branching. It has a molecular weight of 500,000 Da and specific rotation of +1 ...
:L03AX02 Roquinimex :L03AX03
BCG vaccine Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recommended ...
:L03AX04 Pegademase :L03AX05 Pidotimod :L03AX07 Poly I:C :L03AX08 Poly ICLC :L03AX09 Thymopentin :L03AX10 Immunocyanin :L03AX11 Tasonermin :L03AX12 Melanoma vaccine :L03AX13
Glatiramer acetate Glatiramer acetate (also known as Copolymer 1, Cop-1), sold under the brand name Copaxone among others, is an immunomodulator medication used to treat multiple sclerosis. Glatiramer acetate is approved in the United States to reduce the frequenc ...
:L03AX14 Histamine dihydrochloride :L03AX15 Mifamurtide :L03AX16
Plerixafor Plerixafor ( INN and USAN, trade name Mozobil) is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients into the bloodstream. The stem cells are then extracted from the blood and transplanted back to the patient. The dr ...
:L03AX17 Sipuleucel-T :L03AX18 Cridanimod :L03AX19 Dasiprotimut-T :L03AX21 Elapegademase :QL03AX90 Feline
interleukin-2 Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16  kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible fo ...
recombinant canarypox virus ( viral vector)


References

{{Immunostimulants L03