AR-A000002 is a
drug which is one of the first compounds developed to act as a
selective antagonist for the
serotonin receptor 5-HT1B, with approximately 10x selectivity for 5-HT
1B over the closely related
5-HT1D receptor. It has been shown to produce sustained increases in levels of serotonin in the brain, and has
anxiolytic
An anxiolytic (; also antipanic or antianxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxiet ...
effects in animal studies.
References
{{Serotonergics
5-HT1B antagonists
4-Morpholinyl compunds
Benzamides
Phenylpiperazines
Aminotetralins