4-DAMP (1,1-dimethyl-4-diphenylacetoxypiperidinium iodide) is a selective

muscarinic acetylcholine receptor Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-rec ...

(mAChR) M₃ antagonist. It is also able to antagonize M₁ receptors but "prefers" M₃. It competitively binds to the acetylcholine binding site on mAChRs, causing right-ward shift in the dose response curves for mAChR agonists.

References

Muscarinic antagonists Iodides Carboxylate esters Piperidines Quaternary ammonium compounds {{organic-compound-stub