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Poxviridae
''Poxviridae'' is a family of double-stranded DNA viruses. Vertebrates and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Diseases associated with this family include smallpox. Four genera of poxviruses may infect humans: ''Orthopoxvirus'', ''Parapoxvirus'', ''Yatapoxvirus'', ''Molluscipoxvirus''. ''Orthopoxvirus'': smallpox virus (variola), vaccinia virus, cowpox virus, monkeypox virus; ''Parapoxvirus'': orf virus, pseudocowpox, bovine papular stomatitis virus; ''Yatapoxvirus'': tanapox virus, yaba monkey tumor virus; ''Molluscipoxvirus'': molluscum contagiosum virus (MCV). The most common are vaccinia (seen on the Indian subcontinent) and molluscum contagiosum, but monkeypox infections are rising (seen in west and central African rainforest countries). The similarly named disease chickenpox is not a true poxvirus and is caused by the herpesvirus varicella zoster. Etymolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making it the only human disease to be eradicated. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was spread between people or via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medication may have helped. The risk of death was about 30%, with higher rates among babies. Often, those who survived had extensive scarring of their ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molluscipoxvirus
''Molluscum contagiosum virus'' (MCV) is a species of DNA poxvirus that causes the human skin infection molluscum contagiosum. Molluscum contagiosum affects about 200,000 people a year, about 1% of all diagnosed skin diseases. Diagnosis is based on the size and shape of the skin lesions and can be confirmed with a biopsy, as the virus cannot be routinely cultured. ''Molluscum contagiosum virus'' is the only species in the genus ''Molluscipoxvirus''. MCV is a member of the subfamily ''Chordopoxvirinae'' of family ''Poxviridae''. Other commonly known viruses that reside in the subfamily ''Chordopoxvirinae'' are '' variola virus'' (cause of smallpox) and '' monkeypox virus''. The poxvirus family uniquely contains both non-enveloped particles (mature virions), and enveloped particles (extracellular virions). The structure of the virions is consistent with that of others in the poxvirus family: they are composed of a nucleocapsid, core envelope, lateral body, and an extracellular e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccinia
''Vaccinia virus'' (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family. It has a linear, double-stranded DNA genome approximately 190 kbp in length, which encodes approximately 250 genes. The dimensions of the virion are roughly 360 × 270 × 250 nm, with a mass of approximately 5–10 fg. The vaccinia virus is the source of the modern smallpox vaccine, which the World Health Organisation used to eradicate smallpox in a global vaccination campaign in 1958–1977. Although ''smallpox'' no longer exists in the wild, ''vaccinia'' virus is still studied widely by scientists as a tool for gene therapy and genetic engineering. Smallpox had been an endemic human disease that had a 30% fatality rate. In 1796, the British doctor Edward Jenner proved that an infection with the relatively mild cowpox virus would also confer immunity to the deadly smallpox. Jenner referred to cowpox as ''variolae vaccinae'' (smallpox of the cow). However, the origin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudocowpox
Pseudocowpox is a disease caused by the Paravaccinia virus or Pseudocowpox virus, a virus of the family ''Poxviridae'' and the genus '' Parapoxvirus''. Humans can contract the virus from contact with livestock infected with Bovine papular stomatitis and the disease is common among ranchers, milkers, and veterinarians. Infection in humans will present with fever, fatigue, and lesion on the skin. Signs and symptoms Paravaccinia virus presents itself with blisters, nodules, or lesions about 4 mm in diameter, typically in the area that has made contact with livestock that is infected with bovine papular stomatitis. Lesions may begin forming as late as three weeks after contact has been made with an infected animal. In rare cases, lesions may be seen systemic. General signs of infection are also common, such as fever and fatigue. Infected livestock may present with blisters or lesions on their udders or snout. Often, however, infected livestock show little to no symptoms. Mec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acne Scarring
Acne, also known as ''acne vulgaris'', is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and possible scarring. It primarily affects skin with a relatively high number of oil glands, including the face, upper part of the chest, and back. The resulting appearance can lead to anxiety, reduced self-esteem, and, in extreme cases, depression or thoughts of suicide. Susceptibility to acne is primarily genetic in 80% of cases. The roles of diet and cigarette smoking in the condition are unclear, and neither cleanliness nor exposure to sunlight appear to play a part. In both sexes, hormones called androgens appear to be part of the underlying mechanism, by causing increased production of sebum. Another common factor is the excessive growth of the bacterium ''Cutibacterium acnes'', which is present on the skin. Treatments for acne are a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus Classification
Virus classification is the process of naming viruses and placing them into a taxonomic system similar to the classification systems used for cellular organisms. Viruses are classified by phenotypic characteristics, such as morphology, nucleic acid type, mode of replication, host organisms, and the type of disease they cause. The formal taxonomic classification of viruses is the responsibility of the International Committee on Taxonomy of Viruses (ICTV) system, although the Baltimore classification system can be used to place viruses into one of seven groups based on their manner of mRNA synthesis. Specific naming conventions and further classification guidelines are set out by the ICTV. A catalogue of all the world's known viruses has been proposed and, in 2013, some preliminary efforts were underway. Definitions Species definition Species form the basis for any biological classification system. Before 1982, it was thought that viruses could not be made to fit Ernst May ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Micrograph Of Poxvirus Particles In Synovium Of A Big Brown Bat And Negative Staining Of Poxvirus Particles In Cell Culture Supernatant
The electron ( or ) is a subatomic particle with a negative one elementary electric charge. Electrons belong to the first generation of the lepton particle family, and are generally thought to be elementary particles because they have no known components or substructure. The electron's mass is approximately 1/1836 that of the proton. Quantum mechanical properties of the electron include an intrinsic angular momentum (spin) of a half-integer value, expressed in units of the reduced Planck constant, . Being fermions, no two electrons can occupy the same quantum state, in accordance with the Pauli exclusion principle. Like all elementary particles, electrons exhibit properties of both particles and waves: They can collide with other particles and can be diffracted like light. The wave properties of electrons are easier to observe with experiments than those of other particles like neutrons and protons because electrons have a lower mass and hence a longer de Broglie waveleng ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharaoh
Pharaoh (, ; Egyptian: '' pr ꜥꜣ''; cop, , Pǝrro; Biblical Hebrew: ''Parʿō'') is the vernacular term often used by modern authors for the kings of ancient Egypt who ruled as monarchs from the First Dynasty (c. 3150 BC) until the annexation of Egypt by the Roman Empire in 30 BC. However, regardless of gender, "king" was the term used most frequently by the ancient Egyptians for their monarchs through the middle of the Eighteenth Dynasty during the New Kingdom. The term "pharaoh" was not used contemporaneously for a ruler until a possible reference to Merneptah, c. 1210 BC during the Nineteenth Dynasty, nor consistently used until the decline and instability that began with the Twenty-Fifth Dynasty. In the early dynasties, ancient Egyptian kings had as many as three titles: the Horus, the Sedge and Bee ( ''nswt-bjtj''), and the Two Ladies or Nebty ( ''nbtj'') name. The Golden Horus and the nomen and prenomen titles were added later. In Egyptian society, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ramses V
Usermaatre Sekheperenre Ramesses V (also written Ramses and Rameses) was the fourth pharaoh of the Twentieth Dynasty of Egypt and was the son of Ramesses IV and Duatentopet. Reign Ramesses V's reign was characterized by the continued growth of the power of the priesthood of Amun, which controlled much of the temple land in the country and the state finances, at the expense of the ruling pharaohs. The Turin 1887 papyrus records a financial scandal during Ramesses' reign that involved the priests of Elephantine. A period of domestic instability also afflicted his reign, as evidenced by the fact that, according to the Turin Papyrus Cat. 2044, the workmen of Deir el-Medina periodically stopped work on Ramesses V's KV9 tomb in this king's first regnal year, out of fear of "''the enemy''", presumably Libyan raiding parties, who had reached the town of Per-Nebyt and "''burnt its people''." Another incursion by these raiders into Thebes is recorded a few days later.Peden, p.21 This show ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taxonomy
Taxonomy is the practice and science of categorization or classification. A taxonomy (or taxonomical classification) is a scheme of classification, especially a hierarchical classification, in which things are organized into groups or types. Among other things, a taxonomy can be used to organize and index knowledge (stored as documents, articles, videos, etc.), such as in the form of a library classification system, or a search engine taxonomy, so that users can more easily find the information they are searching for. Many taxonomies are hierarchies (and thus, have an intrinsic tree structure), but not all are. Originally, taxonomy referred only to the categorisation of organisms or a particular categorisation of organisms. In a wider, more general sense, it may refer to a categorisation of things or concepts, as well as to the principles underlying such a categorisation. Taxonomy organizes taxonomic units known as "taxa" (singular "taxon")." Taxonomy is different from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Herpesvirus
''Herpesviridae'' is a large family of DNA viruses that cause infections and certain diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word ''ἕρπειν'' ( 'to creep'), referring to spreading cutaneous lesions, usually involving blisters, seen in flares of herpes simplex 1, herpes simplex 2 and herpes zoster (shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established ''Herpesvirus'' as a genus with 23 viruses among four groups. As of 2020, 115 species are recognized, all but one of which are in one of the three subfamilies. Herpesviruses can cause both latent and lytic infections. Nine herpesvirus types are known to primarily infect humans, at least five of which – herpes simplex viruses 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial herpes and genital herpes), varicella zoster virus (or HHV-3; the cause ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Americas
The Americas, which are sometimes collectively called America, are a landmass comprising the totality of North and South America. The Americas make up most of the land in Earth's Western Hemisphere and comprise the New World. Along with their associated islands, the Americas cover 8% of Earth's total surface area and 28.4% of its land area. The topography is dominated by the American Cordillera, a long chain of mountains that runs the length of the west coast. The flatter eastern side of the Americas is dominated by large river basins, such as the Amazon, St. Lawrence River–Great Lakes basin, Mississippi, and La Plata. Since the Americas extend from north to south, the climate and ecology vary widely, from the arctic tundra of Northern Canada, Greenland, and Alaska, to the tropical rain forests in Central America and South America. Humans first settled the Americas from Asia between 42,000 and 17,000 years ago. A second migration of Na-Dene speakers followed later fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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