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Norman Pirie
Norman Wingate (Bill) Pirie FRS (1 July 1907 – 29 March 1997), was a British biochemist and virologist who, along with Frederick Bawden, discovered that a virus can be crystallized by isolating tomato bushy stunt virus in 1936. This was an important milestone in understanding DNA and RNA. Early life Pirie was born in Easebourne, near Midhurst in West Sussex, the youngest of three children of Sir George Pirie, a Scottish painter, and his wife while they were on a visit to England. He was raised near Torrance, East Dunbartonshire. He developed a stammer, and was educated by private tutors and then spent periods at Kelvinside Academy in Glasgow, Harriston School near Dumfries, and Hastings Grammar School, and then from 1921 to 1925 at Rydal School in Colwyn Bay. He studied natural sciences (biochemistry) at Emmanuel College, Cambridge from 1925 to 1929, and became a demonstrator after graduating. He married fellow biochemist Antoinette (Tony) Patey in 1931. They had a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Easebourne
Easebourne () is a village, Anglican parish and civil parish in the Chichester District of West Sussex, England. It is half a mile (0.8 km) north of Midhurst, across the River Rother on the A272 and A286 roads. The parish includes the hamlet of Henley to the north. In the 2001 census there were 708 households with a total population of 1,717 of whom 785 were economically active. History Easebourne (''Eseburne'') was listed in the Domesday Book of 1086 as an ancient Hundred, an extensive area reaching as far afield as Graffham and Cocking to the south, Stedham to the west and Tillington to the east, as well as two hamlets that were not parishes: Todham to the southeast and Buddington to the west; in total it included 12 settlements containing 276 households. In 1861, the population was 859, and the area of the parish . Governance An electoral ward of the same name exists. This ward includes Lodsworth and at the 2011 census had a population of 2,492. Amenities There ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Torrance, East Dunbartonshire
Torrance is a relatively affluent village in East Dunbartonshire, formerly Stirlingshire, Scotland, located north of Glasgow city centre. Torrance used to mainly consist of farmland. The village was once famous as a resting place for workers on their way to the Campsie Fells north. The Forth and Clyde Canal has a wharf nearby at Hungryside, and the A807 runs along its southern edge. The village has an active community charity whose aims are to improve the village facilities. History Originally located in the county of Stirlingshire the name Torrance may come from the Gaelic for the place of the "little hillocks". There are Roman sites close to Torrance with a fort at Cadder and a fortlet at Glasgow Bridge. The village of Torrance is located in "The Eleven Ploughs of Balgrochan". The "Eleven Ploughlands" are part of the estate of the Grahams of Mugdock, which had been feued in 1630 to local occupiers by the Marquess of Montrose. The feuars, originally holding their land unen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ribonucleic Acid
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid ( DNA) are nucleic acids. Along with lipids, proteins, and carbohydrates, nucleic acids constitute one of the four major macromolecules essential for all known forms of life. Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA, RNA is found in nature as a single strand folded onto itself, rather than a paired double strand. Cellular organisms use messenger RNA (''mRNA'') to convey genetic information (using the nitrogenous bases of guanine, uracil, adenine, and cytosine, denoted by the letters G, U, A, and C) that directs synthesis of specific proteins. Many viruses encode their genetic information using an RNA genome. Some RNA molecules play an active role within cells by catalyzing biological reactions, controlling gene expression, or sensing and communicating responses to cellular ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tobacco Mosaic Virus
''Tobacco mosaic virus'' (TMV) is a positive-sense single-stranded RNA virus species in the genus ''Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as "mosaic"-like mottling and discoloration on the leaves (hence the name). TMV was the first virus to be discovered. Although it was known from the late 19th century that a non-bacterial infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus. It is the first pathogen identified as a virus. The virus was crystallised by W.M. Stanley. It has a similar size to the largest synthetic molecule, known as PG5 History In 1886, Adolf Mayer first described the tobacco mosaic disease that could be transferred between plants, similar to bacterial infections. In 1892, Dmitri Ivanovsky gave the first concrete evidence for the existence of a non-bacterial infec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brucellosis
Brucellosis is a highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions. It is also known as undulant fever, Malta fever, and Mediterranean fever. The bacteria causing this disease, '' Brucella'', are small, Gram-negative, nonmotile, nonspore-forming, rod-shaped (coccobacilli) bacteria. They function as facultative intracellular parasites, causing chronic disease, which usually persists for life. Four species infect humans: ''B. abortus'', ''B. canis'', ''B. melitensis'', and ''B. suis''. ''B. abortus'' is less virulent than ''B. melitensis'' and is primarily a disease of cattle. ''B. canis'' affects dogs. ''B. melitensis'' is the most virulent and invasive species; it usually infects goats and occasionally sheep. ''B. suis'' is of intermediate virulence and chiefly infects pigs. Symptoms include profuse sweating and joint and muscle pain. Brucellosis has been recognized in animals a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brucella
''Brucella'' is a genus of Gram-negative bacteria, named after David Bruce (1855–1931). They are small (0.5 to 0.7 by 0.6 to 1.5 µm), non encapsulated, non motile, facultatively intracellular coccobacilli. ''Brucella'' spp. are the cause of brucellosis, which is a zoonosis transmitted by ingesting contaminated food (such as unpasteurized milk products), direct contact with an infected animal, or inhalation of aerosols. Transmission from human to human, for example, through sexual intercourse, or from mother to child, is exceedingly rare, but possible. Minimum infectious exposure is between 10 and 100 organisms. The different species of ''Brucella'' are genetically very similar, although each has a slightly different host specificity. Hence, the National Center for Biotechnology Information taxonomy includes most ''Brucella'' species under ''B. melitensis''. The many names of brucellosis include (human disease/animal disease): * Malta fever/Bang's disease * Undulant fe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ashley Miles (scientist)
Ashley Miles Greig (born March 3, 1985) is a retired American artistic gymnast and current head coach of the Iowa State University Women's Gymnastics team. She was a member of the U.S. women's artistic gymnastics team at the 2001 World Gymnastics Championships in Ghent, Belgium. The U.S. women won the bronze medal in the team event at 2001 Worlds, and Miles qualified to the vault final, where she finished eighth. Elite career A native of San Antonio, Texas, Miles was a member of the U.S. Junior National Team from 1997 to 1998 and 1999–2001, and she was a member of the Senior National Team from 2001 to 2003. At her first U.S. Junior National Championships in Denver, Colorado in 1997, Miles placed second on vault and 10th all-around. Miles placed eighth on vault and 21st all-around at 1998 Junior Nationals in Indianapolis, Indiana. In 1999, she placed second on vault, ninth on balance beam and 12th all-around at 1999 Junior Nationals in Sacramento, California. She also pl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frederick Gowland Hopkins
Sir Frederick Gowland Hopkins (20 June 1861 – 16 May 1947) was an English biochemist who was awarded the Nobel Prize in Physiology or Medicine in 1929, with Christiaan Eijkman, for the discovery of vitamins, even though Casimir Funk, a Polish biochemist, is widely credited with discovering vitamins. He also discovered the amino acid tryptophan, in 1901. He was President of the Royal Society from 1930 to 1935. Education and early life Hopkins was born in Eastbourne, Sussex, and initially attended the City of London School. However, he soon transferred to Alexandra Park College in Hornsey and completed his further study with the University of London External Programme (through evening classes at Birkbeck College) and the medical school at Guy's Hospital which is now part of King's College London School of Medicine. Career and research After graduating, Hopkins then taught physiology and toxicology at Guy's Hospital from 1894 to 1898. In 1898, while attending a meeting of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antoinette Pirie
Antoinette Pirie ( Patey; 4 October 1905 – 11 October 1991) was a British biochemist, ophthalmologist, and educator. Biography Antoinette Patey was born in Bond Street, London. Her father was a botanist and pharmacist. She was educated at Wycombe Abbey School, and then achieved a first-class honours in natural sciences (biochemistry) from Newnham College, Cambridge in 1932. She completed her PhD at the biochemical laboratory in Cambridge under the professorship of Sir Frederick Gowland Hopkins. She married fellow biochemist Norman Pirie in 1931. They had a son and a daughter. Career In 1939, Pirie joined a team at the Imperial Cancer Research Fund's Mill Hill laboratories, led by Ida Mann. The team investigated the effect of mustard gas on the cornea. Pirie was dedicated to the study of the eye for the rest of her life. In 1942, she accompanied Ida Mann to Oxford as her assistant, and in 1947 she succeeded her, as Margaret Ogilvie reader in ophthalmology, at Somerville ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emmanuel College, Cambridge
Emmanuel College is a constituent college of the University of Cambridge. The college was founded in 1584 by Sir Walter Mildmay, Chancellor of the Exchequer to Elizabeth I. The site on which the college sits was once a priory for Dominican monks, and the College Hall is built on the foundations of the monastery's nave. Emmanuel is one of the 16 "old colleges", which were founded before the 17th century. Emmanuel today is one of the larger Cambridge colleges; it has around 500 undergraduates, reading almost every subject taught within the University, and over 150 postgraduates. Among Emmanuel's notable alumni are Thomas Young, John Harvard, Graham Chapman and Sebastian Faulks. Three members of Emmanuel College have received Nobel Prizes: Ronald Norrish, George Porter (both Chemistry, 1967) and Frederick Hopkins (Medicine, 1929). In every year from 1998 until 2016, Emmanuel was among the top five colleges in the Tompkins Table, which ranks colleges according to end-of-ye ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rydal Penrhos
Rydal Penrhos School is an independent day school in Colwyn Bay, North Wales. It is the only Methodist school in the independent sector in Wales. It is located on multiple sites around the town with a site in the neighbouring village of Rhos-on-Sea where it keeps its watersports equipment for easy access to the beach. History The school started life as five separate institutions: *Penrhos College was a Methodist girls-only boarding school founded in 1880 as a result of the generosity of Reverend Frederick Payne (1814-1895), a wealthy benefactor and Wesleyan Methodist minister who lived in Colwyn Bay. It was prominently situated above the promenade towards Rhos-on-Sea. Its motto was ''Semper ad lucem'' ("Always towards the light"). *Rydal School was founded (as Rydal Mount School) by Thomas Osborn in 1885 as a boys’ boarding school. It was named after the house, at the junction of Lansdowne Road and Pwllycrochan Avenue in Colwyn Bay, which Osborn had acquired from Reverend ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hastings Grammar School
Hastings () is a large seaside town and borough in East Sussex on the south coast of England, east to the county town of Lewes and south east of London. The town gives its name to the Battle of Hastings, which took place to the north-west at Senlac Hill in 1066. It later became one of the medieval Cinque Ports. In the 19th century, it was a popular seaside resort, as the railway allowed tourists and visitors to reach the town. Today, Hastings is a fishing port with the UK's largest beach-based fishing fleet. It has an estimated population of 92,855 as of 2018. History Early history The first mention of Hastings is found in the late 8th century in the form ''Hastingas''. This is derived from the Old English tribal name '' Hæstingas'', meaning 'the constituency (followers) of Hæsta'. Symeon of Durham records the victory of Offa in 771 over the ''Hestingorum gens'', that is, "the people of the Hastings tribe." Hastingleigh in Kent was named after that tribe. The place ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
