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Monsanto
The Monsanto Company () was an American agrochemical and agricultural biotechnology corporation founded in 1901 and headquartered in Creve Coeur, Missouri. Monsanto's best known product is Roundup, a glyphosate-based herbicide, developed in the 1970s. Later the company became a major producer of genetically engineered crops. In 2018, the company ranked 199th on the Fortune 500 of the largest United States corporations by revenue. Monsanto was one of four groups to introduce genes into plants in 1983, and was among the first to conduct field trials of genetically modified crops in 1987. It was one of the top 10 US chemical companies until it divested most of its chemical businesses between 1997 and 2002, through a process of mergers and spin-offs that focused the company on biotechnology. Monsanto was one of the first companies to apply the biotechnology industry business model to agriculture, using techniques developed by biotech drug companies. In this business model, com ...
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Glyphosate
Glyphosate (IUPAC name: ''N''-(phosphonomethyl)glycine) is a broad-spectrum systemic herbicide and crop desiccant. It is an organophosphorus compound, specifically a phosphonate, which acts by inhibiting the plant enzyme 5-enolpyruvylshikimate-3-phosphate synthase. It is used to kill weeds, especially annual broadleaf weeds and grasses that compete with crops. Its herbicidal effectiveness was discovered by Monsanto chemist John E. Franz in 1970. Monsanto brought it to market for agricultural use in 1974 under the trade name Roundup. Monsanto's last commercially relevant United States patent expired in 2000. Farmers quickly adopted glyphosate for agricultural weed control, especially after Monsanto introduced glyphosate-resistant Roundup Ready crops, enabling farmers to kill weeds without killing their crops. In 2007, glyphosate was the most used herbicide in the United States' agricultural sector and the second-most used (after 2,4-D) in home and garden, government and ...
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Polychlorinated Biphenyls
Polychlorinated biphenyls (PCBs) are highly carcinogenic chemical compounds, formerly used in industrial and consumer products, whose production was banned in the United States by the Toxic Substances Control Act in 1979 and internationally by the Stockholm Convention on Persistent Organic Pollutants in 2001. They are organic chlorine compounds with the formula C12 H10−''x'' Cl''x''; they were once widely used in the manufacture of carbonless copy paper, as heat transfer fluids, and as dielectric and coolant fluids for electrical equipment. Because of their longevity, PCBs are still widely in use, even though their manufacture has declined drastically since the 1960s, when a host of problems were identified. With the discovery of PCBs' environmental toxicity, and classification as persistent organic pollutants, their production was banned by United States federal law in 1978, and by the Stockholm Convention on Persistent Organic Pollutants in 2001. The International Ag ...
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Roundup (herbicide)
Roundup is the brand name of a systemic, broad-spectrum glyphosate-based herbicide originally produced by Monsanto, which Bayer acquired in 2018. Glyphosate is the most widely used herbicide in the United States. , work=U.S. Environmental Protection Agency , title=EPA 2000 Pesticide Market Estimates , url=http://www.epa.gov/oppbead1/pestsales/01pestsales/usage2001_2.htm#3_6 Agriculture] As of 2009, sales of Roundup herbicides still represented about 10 percent of Monsanto's revenue despite competition from Chinese producers of other glyphosate-based herbicides. The overall Roundup line of products, which includes genetically modified seeds, represented about half of Monsanto's yearly revenue. The product is marketed to consumers by Scotts Miracle-Gro Company. Monsanto developed and patented the glyphosate molecule in the 1970s, and marketed it as Roundup from 1973. It retained exclusive rights to glyphosate in the US until its US patent expired in September 2000; in o ...
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Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceuticals; consumer healthcare products, agricultural chemicals, seeds and biotechnology products. The company is a component of the Euro Stoxx 50 stock market index. Bayer was founded in 1863 in Barmen as a partnership between dye salesman Friedrich Bayer and dyer Friedrich Weskott. As was common in this era, the company was established as a dyestuffs producer. The versatility of aniline chemistry led Bayer to expand their business into other areas, and in 1899 Bayer launched the compound acetylsalicylic acid under the trademarked name Aspirin. In 1904 Bayer received a trademark for the "Bayer Cross" logo, which was subsequently stamped onto each aspirin tablet, creating an iconic product that is still sold by Bayer. Other commonly known prod ...
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Bovine Somatotropin
Bovine somatotropin or bovine somatotrophin (abbreviated bST and BST), or bovine growth hormone (BGH), is a peptide hormone produced by cows' pituitary glands. Like other hormones, it is produced in small quantities and is used in regulating metabolic processes. Recombinant bovine somatotropin (usually "rBST"), is a synthetic version of the bovine growth hormone given to dairy cattle by injection to increase milk production. Synthesis After the biotech company Genentech discovered and patented the gene for BST in the 1970s,Keith Schneider. 10 June 1990"Betting the Farm on Biotech." ''the New York Times'' it became possible to synthesize the hormone using recombinant DNA technology to create recombinant bovine somatotropin (rBST), recombinant bovine growth hormone (rBGH), or artificial growth hormone. Industrial production Four large pharmaceutical companies, Monsanto, American Cyanamid, Eli Lilly, and Upjohn, developed commercial rBST products and submitted them to the US ...
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Genetically Modified Crops
Genetically modified crops (GM crops) are plants used in agriculture, the DNA of which has been modified using genetic engineering methods. Plant genomes can be engineered by physical methods or by use of ''Agrobacterium'' for the delivery of sequences hosted in T-DNA binary vectors. In most cases, the aim is to introduce a new trait to the plant which does not occur naturally in the species. Examples in food crops include resistance to certain pests, diseases, environmental conditions, reduction of spoilage, resistance to chemical treatments (e.g. resistance to a herbicide), or improving the nutrient profile of the crop. Examples in non-food crops include production of pharmaceutical agents, biofuels, and other industrially useful goods, as well as for bioremediation. Farmers have widely adopted GM technology. Acreage increased from 1.7 million hectares in 1996 to 185.1 million hectares in 2016, some 12% of global cropland. As of 2016, major crop (soybean, maize, canola ...
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John Francis Queeny
John Francis Queeny (August 17, 1859 – March 19, 1933) was an American businessman, known for founding Monsanto Chemical Works (later Monsanto) in St. Louis, Missouri, on September 26, 1901, with $5,000. He named the company for his wife, Olga Mendez Monsanto. Early life Born in Chicago, Illinois, he attended school for six years until the Great Chicago Fire forced him to seek full-time employment at age 12. Queeny got a job with Tolman and King for $2.50 per week. Career He moved to St. Louis in 1897 to work for Meyer Brothers Drug Company, one of the largest wholesale pharmaceutical companies at the time. Two years later, he spent his life savings in purchasing a sulfur refinery; it burned down the next day. Two years after that, he founded Monsanto Chemical Works, and began producing saccharine, which he sold to Meyer Brothers. He started to turn a profit in 1905, but it was not until 1906 that he left Meyer Brothers to work for Monsanto full-time. In 1928, Queeny re ...
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Agent Orange
Agent Orange is a chemical herbicide and defoliant, one of the "tactical use" Rainbow Herbicides. It was used by the U.S. military as part of its herbicidal warfare program, Operation Ranch Hand, during the Vietnam War from 1961 to 1971. It is a mixture of equal parts of two herbicides, 2,4,5-T and 2,4-D. In addition to its damaging environmental effects, traces of dioxin (mainly TCDD, the most toxic of its type) found in the mixture have caused major health problems for many individuals who were exposed, and their offspring. Agent Orange was produced in the United States from the late 1940s and was used in industrial agriculture and was also sprayed along railroads and power lines to control undergrowth in forests. During the Vietnam War, the U.S. military procured over 20 million gallons consisting of a fifty-fifty mixture of 2,4-D and dioxin-contaminated 2,4,5-T. Nine chemical companies produced it: Dow Chemical Company, Monsanto Company, Diamond Shamrock Corporati ...
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Hugh Grant (business Executive)
Hugh Grant (born 23 March 1958) is a Scottish business executive, who was the last CEO of Monsanto until its acquisition by Bayer. Early life Grant was born in Larkhall, Scotland. He received a bachelor's degree in agricultural zoology and molecular biology from the University of Glasgow, a postgraduate degree in agriculture from the University of Edinburgh, and an MBA from the International Management Centre in Buckingham, England. Career He worked in Scotland from 1981 to 1991 for the then US-based Monsanto company and then was appointed global strategy director in the agriculture division, based in St. Louis, Missouri. In 1995, he became managing director for the company's Asia-Pacific region and in 1998, co-president of the agriculture division. The 20th-century Monsanto Company, in the midst of a roughly five-year series of mergers and spin-offs (which had the effect of reducing its focus on chemicals in favor of biotechnology), legally ceased to exist in 2000. A new ...
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Pharmacia & Upjohn
Pharmacia & Upjohn was a global pharmaceutical company formed by the merger of Sweden-based Pharmacia AB and the American company Upjohn in 1995. Today the remainder of the company is owned by Pfizer. In 1997, Pharmacia & Upjohn sold several brands to Johnson & Johnson, including Motrin and Cortaid. History Amersham In 1997, the biotechnology division of the company Pharmacia Biotech merged with Amersham Life Science with the new merged entity being known as Amersham Pharmacia Biotech. In 2001, the company was renamed Amersham Biotech. In 2002, Pharmacia sold its share of the company to Amersham plc. In 2004, Amersham Biosciences was acquired by GE Healthcare. In 1998, the nutrition division of the company was sold to Fresenius. Monsanto Monsanto acquired the pharmaceutical company G. D. Searle & Company in 1985. In 1998, Searle and the Monsanto Pharma Sector partnered with Pfizer to develop and promote celecoxib, an anti-inflammatory drug used to treat arthritis. Branded a ...
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Creve Coeur, Missouri
Creve Coeur is a city located in mid St. Louis County, Missouri, United States, a part of Greater St. Louis. Its population was 18,834 at the 2020 census. Creve Coeur borders and shares a ZIP code (63141) with the neighboring city of Town and Country. It is home to the headquarters of Drury Hotels, and Monsanto until its acquisition by Bayer in 2018. History The name ''crève cœur'' (, "heartbreak") is said to derive from Creve Coeur Lake. According to the city's website, the tale goes that the lake "formed itself into a broken heart" after an Indian princess's unrequited love for a French fur trapper led her to jump "from a ledge overlooking" the lake. Written accounts and archaeological finds show that Native Americans inhabited the Creve Coeur area from 9500 BC to 1800 AD. French explorers began farming and fishing in the area in the early 18th century, and fur trappers settled there in the early 19th century. When the area was acquired by the United States through the ...
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Herbicide
Herbicides (, ), also commonly known as weedkillers, are substances used to control undesired plants, also known as weeds.EPA. February 201Pesticides Industry. Sales and Usage 2006 and 2007: Market Estimates. Summary in press releasMain page for EPA reports on pesticide use ihere Selective herbicides control specific weed species, while leaving the desired crop relatively unharmed, while non-selective herbicides (sometimes called total weedkillers in commercial products) can be used to clear waste ground, industrial and construction sites, railways and railway embankments as they kill all plant material with which they come into contact. Apart from selective/non-selective, other important distinctions include ''persistence'' (also known as ''residual action'': how long the product stays in place and remains active), ''means of uptake'' (whether it is absorbed by above-ground foliage only, through the roots, or by other means), and ''mechanism of action'' (how it works). Historic ...
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