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Lurtotecan
Lurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposome, Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued. Synthesis * Heck reaction * Mitsunobu reaction * Potassium osmate * Sharpless asymmetric dihydroxylation * Swern oxidation References [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lurtotecan Synthesis
Lurtotecan is a semi-synthetic analog of camptothecin with antineoplastic activity. Liposome, Liposomal lurtotecan was in clinical trials as a treatment for topotecan-resistant ovarian cancer, but was discontinued. Synthesis * Heck reaction * Mitsunobu reaction * Potassium osmate * Sharpless asymmetric dihydroxylation * Swern oxidation References [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
