Konrad E. Bloch
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Konrad E. Bloch
Konrad Emil Bloch (; 21 January 1912 – 15 October 2000) was a German-American biochemist. Bloch received the Nobel Prize in Physiology or Medicine in 1964 (joint with Feodor Lynen) for discoveries concerning the mechanism and regulation of the cholesterol and fatty acid metabolism.Konrad E. Bloch
Encyclopaedia Britannica


Life and career

Bloch was born in Neisse (Nysa), in the German Empire's

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Nysa, Poland
Nysa (german: Neisse or ''Neiße'', szl, Nysa) is a town in southwestern Poland on the Eastern Neisse ( Polish: ''Nysa Kłodzka'') river, situated in the Opole Voivodeship. With 43,849 inhabitants (2019), it is the capital of Nysa County. It comprises the urban portion of the surrounding Gmina Nysa. Historically the town was part of Upper Silesia. History Nysa, one of the oldest towns in Silesia, was probably founded in the 10th century. The name of the Nysa river, from which the town takes its name, was mentioned in 991, when the region formed part of the Duchy of Poland under Mieszko I of Poland. A Polish stronghold was built in Nysa in the 11th and 12th century due to the proximity of the border with the Czech Duchy. As a result of the fragmentation of Poland, it became part of the Duchy of Silesia, and from the 14th century it functioned as the capital of the Duchy of Nysa, administered by the Bishopric of Wrocław. In the 12th century the Gothic Basilica of S ...
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Technical University Of Munich
The Technical University of Munich (TUM or TU Munich; german: Technische Universität München) is a public research university in Munich, Germany. It specializes in engineering, technology, medicine, and applied and natural sciences. Established in 1868 by King Ludwig II of Bavaria, the university now has additional campuses in Garching, Freising, Heilbronn, Straubing, and Singapore, with the Garching campus being its largest. The university is organized into eight schools and departments, and is supported by numerous research centers. It is one of the largest universities in Germany, with 50,000 students and an annual budget of €1,770.3 million (including university hospital). A ''University of Excellence'' under the German Universities Excellence Initiative, TUM is considered the top university in Germany according to major rankings as of 2022 and is among the leading universities in the European Union. Its researchers and alumni include 18 Nobel laureates and 23 Leibniz ...
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Fungi
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''t ...
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Squalene
Squalene is an organic compound. It is a triterpenoid with the formula C30H50. It is a colourless oil, although impure samples appear yellow. It was originally obtained from shark liver oil (hence its name, as ''Squalus'' is a genus of sharks). All plants and animals produce squalene as a biochemical intermediate to sterol biosynthesis. An estimated 12% of bodily squalene in humans is found in sebum. Squalene has a role in topical skin lubrication and protection. Squalene is a precursor for synthesis of all plant and animal sterols, including cholesterol and steroid hormones in the human body. Squalene is an important ingredient in some vaccine adjuvants: The Novartis and GlaxoSmithKline adjuvants are called MF59 and AS03, respectively. Role in steroid synthesis Squalene is the biochemical precursor to steroids. The squalene conversion begins with oxidation (via squalene monooxygenase) of one of its terminal double bonds, resulting in 2,3-oxidosqualene. It then undergoes an ...
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Fatty Acid
In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, from 4 to 28. Fatty acids are a major component of the lipids (up to 70% by weight) in some species such as microalgae but in some other organisms are not found in their standalone form, but instead exist as three main classes of esters: triglycerides, phospholipids, and cholesteryl esters. In any of these forms, fatty acids are both important dietary sources of fuel for animals and important structural components for cells. History The concept of fatty acid (''acide gras'') was introduced in 1813 by Michel Eugène Chevreul, though he initially used some variant terms: ''graisse acide'' and ''acide huileux'' ("acid fat" and "oily acid"). Types of fatty acids Fatty acids are classified in many ways: by length, by saturation vs unsa ...
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Florida State University
Florida State University (FSU) is a public university, public research university in Tallahassee, Florida. It is a senior member of the State University System of Florida. Founded in 1851, it is located on the oldest continuous site of higher education in the state of Florida. Florida State University comprises 16 separate colleges and more than 110 centers, facilities, labs and institutes that offer more than 360 programs of study, including professional school programs. In 2021, the university enrolled 45,493 students from all 50 states and 130 countries. Florida State is home to Florida's only national laboratory, the National High Magnetic Field Laboratory, and is the birthplace of the commercially viable anti-cancer drug Taxol. Florida State University also operates the John & Mable Ringling Museum of Art, the State Art Museum of Florida and one of the largest museum/university complexes in the nation. The university is accredited by the Southern Association of Colleges and ...
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Harvard T
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inc ...
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Eugene Higgins
Eugene Higgins (1860 – 1948) was the rich heir to a carpet-making business, known as a ''bon vivant'', sportsman, and philanthropist. A bachelor, when he died in 1948, his estate went to establish the Higgins Trust, at that time, the eleventh largest of its kind in the USA. Background Eugene Higgins was born on January 14, 1860, in New York City. His parents were Elias Smith Higgins (1815–1889), a carpet manufacturer who made a fortune with "labor-saving devices," and Emma Louise Baldwin (1827–1890). In 1882, he graduated from Columbia University, where he was a classmate of future Columbia president Nicholas Murray Butler. Career Higgins never worked for a living, though he did maintain a private office at 50 Union Square East. In 1908, his steam yacht the ''Varuna'' wrecked off the Madeira Islands; he received a medal for saving lives of several guests aboard. A sportsman, Higgins won the 1890 American fencing championship and was a proficient golfer, hunter, fish ...
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Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endow ...
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University Of Chicago
The University of Chicago (UChicago, Chicago, U of C, or UChi) is a private university, private research university in Chicago, Illinois. Its main campus is located in Chicago's Hyde Park, Chicago, Hyde Park neighborhood. The University of Chicago is consistently ranked among the best universities in the world and it is among the most selective in the United States. The university is composed of College of the University of Chicago, an undergraduate college and five graduate research divisions, which contain all of the university's graduate programs and interdisciplinary committees. Chicago has eight professional schools: the University of Chicago Law School, Law School, the Booth School of Business, the Pritzker School of Medicine, the Crown Family School of Social Work, Policy, and Practice, the Harris School of Public Policy, the University of Chicago Divinity School, Divinity School, the Graham School of Continuing Liberal and Professional Studies, and the Pritzker School of ...
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Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, Columbia is the oldest institution of higher education in New York and the fifth-oldest institution of higher learning in the United States. It is one of nine colonial colleges founded prior to the Declaration of Independence. It is a member of the Ivy League. Columbia is ranked among the top universities in the world. Columbia was established by royal charter under George II of Great Britain. It was renamed Columbia College in 1784 following the American Revolution, and in 1787 was placed under a private board of trustees headed by former students Alexander Hamilton and John Jay. In 1896, the campus was moved to its current location in Morningside Heights and renamed Columbia University. Columbia scientists and scholars have ...
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Yale Medical School
The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary teaching hospital for the school is Yale New Haven Hospital. The school is home to the Harvey Cushing/John Hay Whitney Medical Library, one of the largest modern medical libraries which is known for its historical collections. The faculty includes 70 National Academy of Sciences members, 47 National Academy of Medicine members, and 13 Howard Hughes Medical Institute investigators. '' U.S. News & World Report'' currently ranks the Yale School of Medicine 10th in the country for research and 59th in primary care. The MD program is highly selective; for the class of 2022, the school received 4,968 applications to fill 104 seats. The median GPA for the class was 3.89, and the median MCAT was 521. Education The School of Medicine offers the ...
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