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John W. Huffman
John William Huffman (born 1932) is a professor emeritus of organic chemistry at Clemson University
Clemson University
who first synthesised many novel cannabinoids.[1] His research, funded by the National Institute on Drug Abuse, was focused on making a drug to target endocannabinoid receptors in the body.[2]Contents1 Cannabinoid
Cannabinoid
research 2 Law enforcement 3 External links 4 See also 5 References Cannabinoid
Cannabinoid
research[edit] Beginning in 1984, Huffman and his team of researchers began developing cannabinoid compounds to aid in research of multiple sclerosis, HIV/AIDS, and chemotherapy. Over the course of twenty years, Huffman and his team developed 450 synthetic cannabinoid compounds which were used to test the effect of cannabinoid receptors in the brain and other organs
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Northwestern University
Northwestern University
University
(NU) is a private research university based in Evanston, Illinois, United States, with other campuses located in Chicago
Chicago
and Doha, Qatar, and academic programs and facilities in
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Harvard University
Harvard University
Harvard University
is a private Ivy League
Ivy League
research university in Cambridge, Massachusetts. Established in 1636 and named for clergyman John Harvard (its first benefactor), its history, influence, and wealth have made it one of the world's most prestigious universities.[8] Harvard is the United States' oldest institution of higher learning,[9] and the Harvard Corporation
Harvard Corporation
(formally, the President and Fellows of Harvard College) is its first chartered corporation. Although never formally affiliated with any denomination, the early College primarily trained Congregational and Unitarian clergy. Its curriculum and student body were gradually secularized during the 18th century, and by the 19th century, Harvard had emerged as the central cultural establishment among Boston elites.[10][11] Following the American Civil War, President Charles W
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Endocannabinoid
The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the mammalian central nervous system (including the brain) and peripheral nervous system. The endocannabinoid system is involved in regulating a variety of physiological and cognitive processes including fertility,[1] pregnancy,[2] during pre- and postnatal development,[3] appetite, pain-sensation, mood, and memory, and in mediating the pharmacological effects of cannabis.[4][5] The ECS is also involved in mediating some of the physiological and cognitive effects of voluntary physical exercise in humans and other animals, such as contributing to exercise-induced euphoria as well as modulating locomotor activity and motivational salience for rewards.[6][7][8][9] In humans, the plasma concentration of certain endocannabinoids (i.e., anandamide)
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HIV/AIDS
Human immunodeficiency virus
Human immunodeficiency virus
infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).[9][10][11] Following initial infection, a person may not notice any symptoms or may experience a brief period of influenza-like illness.[5] Typically, this is followed by a prolonged period with no symptoms.[6] As the infection progresses, it interferes more with the immune system, increasing the risk of common infections like tuberculosis, as well as other o
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Washington Post
The Washington Post
The Washington Post
is an American daily newspaper. Published in Washington, D.C., it was founded on December 6, 1877.[7] Located in the capital city of the United States, the newspaper has a particular emphasis on national politics. The newspaper's slogan states, "Democracy dies in darkness". Daily editions are printed for the District of Columbia, Maryland, and Virginia. It is published as a broadsheet. The newspaper has won 47 Pulitzer Prizes. This includes six separate Pulitzers awarded in 2008, second only to The New York Times' seven awards in 2002 for the highest number ever awarded to a single newspaper in one year.[8] Post journalists have also received 18 Nieman Fellowships and 368 White House
White House
News Photographers Association awards
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Special
Special
Special
or specials may refer to:Contents1 Music 2 Film and television 3 Other uses 4 See alsoMusic[edit] Special
Special
(album), a 1992
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Cannabinoid
A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain. Ligands for these receptor proteins include the endocannabinoids (produced naturally in the body by animals),[1] the phytocannabinoids (found in cannabis and some other plants), and synthetic cannabinoids (manufactured artificially)
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JWH-018
JWH-018
JWH-018
(1-pentyl-3-(1-naphthoyl)indole) or AM-678[1] is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. It produces effects in animals similar to those of tetrahydrocannabinol (THC), a cannabinoid naturally present in cannabis, leading to its use in synthetic cannabis products such as "legal cannabis herbal incense blends" which in some countries are sold legally as "incense", labeled "not for human consumption".[2][3][4][5][6]Contents1 History 2 Pharmacology2.1 Pharmacokinetics3 Usage 4 Detection in biological fluids 5 Legal status 6 Synthesis 7 See also 8 References 9 External linksHistory[edit] John W. Huffman, an organic chemist at Clemson University, synthesized a variety of chemical compounds that affect the endocannabinoid system
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List Of JWH Cannabinoids
The John W. Huffman research group at Clemson University
Clemson University
synthesized over 450 cannabinoids
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Clemson University
Clemson University
University
/ˈklɛmsən/[5] is an American public, coeducational, land-grant and sea-grant research university in Clemson, South Carolina. Founded in 1889, Clemson is the second largest university in student population in South Carolina. For the fall 2016 semester, the university enrolled a total of 18,599 undergraduate students and 4,807 graduate students,[3] and the student/faculty ratio was 16:1.[6] Clemson's 1,400 acre campus [7] is located in the foothills of the Blue Ridge Mountains and sits next to Lake Hartwell
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Synthetic Cannabis
Synthetic cannabinoids
Synthetic cannabinoids
are a class of chemicals that bind to cannabinoid receptors in the body, but that are different from the natural cannabinoids in cannabis plants. They are often marketed as designer drugs or sold in products with claims that they give the effects of cannabis
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National Institute On Drug Abuse
The National Institute on Drug Abuse
National Institute on Drug Abuse
(NIDA) is a United States federal-government research institute whose mission is to "lead the Nation in bringing the power of science to bear on drug abuse and addiction." The institute has conducted an in-depth study of addiction according to its biological, behavioral and social components. It has also supported many treatments such as nicotine patches and gums, and performed research into AIDS and other drug-related diseases
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John W. Huffman
John William Huffman (born 1932) is a professor emeritus of organic chemistry at Clemson University
Clemson University
who first synthesised many novel cannabinoids.[1] His research, funded by the National Institute on Drug Abuse, was focused on making a drug to target endocannabinoid receptors in the body.[2]Contents1 Cannabinoid
Cannabinoid
research 2 Law enforcement 3 External links 4 See also 5 References Cannabinoid
Cannabinoid
research[edit] Beginning in 1984, Huffman and his team of researchers began developing cannabinoid compounds to aid in research of multiple sclerosis, HIV/AIDS, and chemotherapy. Over the course of twenty years, Huffman and his team developed 450 synthetic cannabinoid compounds which were used to test the effect of cannabinoid receptors in the brain and other organs
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