HOT-7
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HOT-7
HOT-7, or 2,5-dimethoxy-4-(β-propylthio)-N-hydroxyphenethylamine, is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book, '' PiHKAL''. Chemistry HOT-7's full chemical name is 2- thio)-2,5-dimethoxy.html" ;"title="propyl">-(2-propylThio-.html" ;"title="propyl.html" ;"title="-(2-propyl">-(2-propylThio-">thio)-2,5-dimethoxy">propyl">-(2-propylThio-.html" ;"title="propyl.html" ;"title="-(2-propyl">-(2-propylThio-">thio)-2,5-dimethoxyphenyl–Nitrogen, N–hydroxyl, hydroxyethanamine. It has structure, structural properties similar to 2C-T-7 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-17. General information The dosage range of HOT-7 is typically 15-25 mg and its duration is approximately 6–8 hours according to Shulgin. HOT-7 produces closed-eye and open-eye visuals. It also induces a feeling similar to that of being drunk. Legality ...
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Drugs Controlled By The UK Misuse Of Drugs Act
These drugs are known in the UK as ''controlled drugs'', because this is the term by which the act itself refers to them. In more general terms, however, many of these drugs are also controlled by the Medicines Act 1968, there are many other drugs which are controlled by the Medicines Act but not by the Misuse of Drugs Act, and some other drugs (alcohol, for example) are controlled by other laws. The Misuse of Drugs Act sets out three separate categories, Class A, Class B, and Class C. Class A drugs represent those deemed most dangerous, and so carry the harshest punishments. Class C represents those thought to have the least capacity for harm, and so the Act demands more lenient punishment. In reality the potential harm has little bearing on the class, which has led to dissatisfaction with drug laws. Being found in possession of a drug on this list is dealt with less seriously than would be if it were deemed that there is intent to supply (even without payment) the drug to ot ...
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HOT-17
HOT-17 (2,5-dimethoxy-4-(β-isobutylthio)-''N''-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It was synthesized by Alexander Shulgin and reported in his book '' PiHKAL''. Chemistry HOT-17's full chemical name is 2- thio)-2,5-dimethoxy.html" ;"title="isobutylThio-.html" ;"title="isobutyl.html" ;"title="-(2-isobutyl">-(2-isobutylThio-">thio)-2,5-dimethoxy">isobutylThio-.html" ;"title="isobutyl.html" ;"title="-(2-isobutyl">-(2-isobutylThio-">thio)-2,5-dimethoxyphenyl-Nitrogen, ''N''-hydroxyl, hydroxyethanamine. It has chemical structure, structural properties similar to 2C-T-17 and to other drugs in the HOT- series, with the most closely related compounds being HOT-2 and HOT-7. General information The dosage range of HOT-17 is typically 70-120 mg and its duration is approximately 12–18 hours according to Shulgin. HOT-17 produces time distortion and general psychedelia. It also has little to no body load. See also *Phenethylamine Pheneth ...
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HOT-2
HOT-2 (2,5-dimethoxy-4-(β-ethylthio)-''N''-hydroxyphenethylamine) is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book '' PiHKAL''. Chemistry HOT-2's full chemical name is 2- thio)-2,5-dimethoxy.html" ;"title="ethyl_group">ethylThio-.html" ;"title="ethyl_group.html" ;"title="-(2-ethyl group">ethylThio-">thio)-2,5-dimethoxy">ethyl_group">ethylThio-.html" ;"title="ethyl_group.html" ;"title="-(2-ethyl group">ethylThio-">thio)-2,5-dimethoxyphenyl–Nitrogen, N–hydroxyl, hydroxyethanamine. It has structure, structural properties similar to 2C-T-2 and to other drugs in the HOT- series, with the most closely related compounds being HOT-7 and HOT-17. General information The dosage range of HOT-2 is typically 10-18 mg and its duration is approximately 6–10 hours according to Shulgin. HOT-2 produces visuals and moving, flowing lights. It also causes euphoria and increases blood pressure. Legality ...
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Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence'' Sometimes, they are called classic hallucinogens, serotonergic hallucinogens, or serotonergic psychedelics, and the term ''psychedelics'' is used more broadly to include all hallucinogens; this article uses the narrower definition of ''psychedelics''. Psychedelics cause specific psychological, visual, and auditory changes, and often a substantially altered state of consciousness.Leary, Timothy; Metzner, Ralph (1964). ''The Psychedelic Experience: A Manual Based on The Tibetan Book of the Dead'' Psychedelic states are often compared to meditative, psychodynamic or transcendental types of alterations of mind. The "classical" psychedelics, the ...
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Structure
A structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized. Material structures include man-made objects such as buildings and machines and natural objects such as biological organisms, minerals and chemicals. Abstract structures include data structures in computer science and musical form. Types of structure include a hierarchy (a cascade of one-to-many relationships), a network featuring many-to-many links, or a lattice featuring connections between components that are neighbors in space. Load-bearing Buildings, aircraft, skeletons, anthills, beaver dams, bridges and salt domes are all examples of load-bearing structures. The results of construction are divided into buildings and non-building structures, and make up the infrastructure of a human society. Built structures are broadly divided by their varying design approaches and standards, into categories including building st ...
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Psychedelic Phenethylamines
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips").Pollan, Michael (2018). ''How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence'' Sometimes, they are called classic hallucinogens, serotonergic hallucinogens, or serotonergic psychedelics, and the term ''psychedelics'' is used more broadly to include all hallucinogens; this article uses the narrower definition of ''psychedelics''. Psychedelics cause specific psychological, visual, and auditory changes, and often a substantially altered state of consciousness.Leary, Timothy; Metzner, Ralph (1964). ''The Psychedelic Experience: A Manual Based on The Tibetan Book of the Dead'' Psychedelic states are often compared to meditative, psychodynamic or transcendental types of alterations of mind. The "classical" psychedelics, the psyc ...
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Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter in the human central nervous system. In mammals, phenethylamine is produced from the amino acid L-phenylalanine by the enzyme aromatic L-amino acid decarboxylase via enzymatic decarboxylation. In addition to its presence in mammals, phenethylamine is found in many other organisms and foods, such as chocolate, especially after microbial fermentation. Phenethylamine is sold as a dietary supplement for purported mood and weight loss-related therapeutic benefits; however, in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by monoa ...
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Drunk
Alcohol intoxication, also known as alcohol poisoning, commonly described as drunkenness or inebriation, is the negative behavior and physical effects caused by a recent consumption of alcohol. In addition to the toxicity of ethanol, the main psychoactive component of alcoholic beverages, other physiological symptoms may arise from the activity of acetaldehyde, a metabolite of alcohol. These effects may not arise until hours after ingestion and may contribute to the condition colloquially known as a hangover. Symptoms of intoxication at lower doses may include mild sedation and poor coordination. At higher doses, there may be slurred speech, trouble walking, and vomiting. Extreme doses may result in a respiratory depression, coma, or death. Complications may include seizures, aspiration pneumonia, injuries including suicide, and low blood sugar. Alcohol intoxication can lead to alcohol-related crime with perpetrators more likely to be intoxicated than victims. Alcoho ...
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Milligram
The kilogram (also kilogramme) is the unit of mass in the International System of Units (SI), having the unit symbol kg. It is a widely used measure in science, engineering and commerce worldwide, and is often simply called a kilo colloquially. It means 'one thousand grams'. The kilogram is defined in terms of the second and the metre, both of which are based on fundamental physical constants. This allows a properly equipped metrology laboratory to calibrate a mass measurement instrument such as a Kibble balance as the primary standard to determine an exact kilogram mass. The kilogram was originally defined in 1795 as the mass of one litre of water. The current definition of a kilogram agrees with this original definition to within 30 parts per million. In 1799, the platinum ''Kilogramme des Archives'' replaced it as the standard of mass. In 1889, a cylinder of platinum-iridium, the International Prototype of the Kilogram (IPK), became the standard of the unit of mass for the ...
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2C-T-7
2C-T-7 is a psychedelic phenethylamine of the 2C family. In his book '' PiHKAL: A Chemical Love Story'', Alexander Shulgin lists the dosage range as 10 to 30 mg. 2C-T-7 is generally taken orally, and produces psychedelic and entactogenic effects that last 8 to 15 hours. Up until Operation Web Tryp and three deaths, two of which involved the use of other drugs in addition to 2C-T-7, and one which involved an excessive insufflated dose, 2C-T-7 was sold commercially in Dutch and Japanese smartshops and online. It is known on the streets as Blue Mystic or 7th Heaven. There has been little real research done on this chemical other than Shulgin's comments in PiHKAL and a few small animal studies mostly aimed at detecting metabolites. Pharmacology The mechanism that produces the psychedelic and entactogenic effects of 2C-T-7 is most likely to result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by most currently-known hallucinogen ...
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Hydroxyl
In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom. In organic chemistry, alcohols and carboxylic acids contain one or more hydroxy groups. Both the negatively charged anion , called hydroxide, and the neutral radical , known as the hydroxyl radical, consist of an unbonded hydroxy group. According to IUPAC definitions, the term ''hydroxyl'' refers to the hydroxyl radical () only, while the functional group is called a ''hydroxy group''. Properties Water, alcohols, carboxylic acids, and many other hydroxy-containing compounds can be readily deprotonated due to a large difference between the electronegativity of oxygen (3.5) and that of hydrogen (2.1). Hydroxy-containing compounds engage in intermolecular hydrogen bonding increasing the electrostatic attraction between molecules and thus to higher boiling and melting points than found for compounds that lack t ...
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Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter in the human central nervous system. In mammals, phenethylamine is produced from the amino acid L-phenylalanine by the enzyme aromatic L-amino acid decarboxylase via enzymatic decarboxylation. In addition to its presence in mammals, phenethylamine is found in many other organisms and foods, such as chocolate, especially after microbial fermentation. Phenethylamine is sold as a dietary supplement for purported mood and weight loss-related therapeutic benefits; however, in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by monoa ...
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