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Frederick Sanger
Frederick Sanger (; 13 August 1918 – 19 November 2013) was an English biochemist who received the Nobel Prize in Chemistry twice. He won the 1958 Chemistry Prize for determining the amino acid sequence of insulin and numerous other proteins, demonstrating in the process that each had a unique, definite structure; this was a foundational discovery for the central dogma of molecular biology. At the newly-constructed Laboratory of Molecular Biology in Cambridge, he developed and subsequently refined the first-ever DNA sequencing technique, which vastly expanded the number of feasible experiments in molecular biology and remains in widespread use today. The breakthrough earned him the 1980 Nobel Prize in Chemistry, which he shared with Walter Gilbert and Paul Berg. He is one of only three people to have won multiple Nobel Prizes in the same category (the others being John Bardeen in physics and Karl Barry Sharpless in chemistry), and one of five persons with two ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rendcomb
Rendcomb is a village in the Cotswold local authority area of the English county of Gloucestershire. It is about five miles north of Cirencester in the Churn valley. History Etymology Remdcomb is thought to get its name from the stream running through the small valley or ''coomb'' which lies south of the village. The stream which flows into the Churn, was called ''Hrindan Broc'' in 852 AD, with the modern name of Rendcomb deriving from ''Hrindan'' + ''coomb''. History In 1086 a total of 39 inhabitants of Rendcomb and Eycot was recorded in the Domesday Book as part of Rapsgate Hundred. By 1563, there were 12 households in Rendcomb. The existence of Rendomb Park estate was recorded in 1544, and by the 1670s it consisted of 250 acres. During the middle ages, Rendcomb manor was the property of the earls of Gloucester and owned by their knights including the de la Mare family. In 1503, the manor was sold to Edmund Tame of Fairford, son of John Tame. Sir Richard Berkley was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Bate Hardy Prize
The William Bate Hardy Prize is awarded by the Cambridge Philosophical Society. It is awarded once in three years “for the best original memoir, investigation or discovery by a member of the University of Cambridge in connection with Biological Science that may have been published during the three years immediately preceding”. Recipients (''incomplete list-prize awarded at least 22 times by 2014'') *1966 Hugh Huxley (inaugural winner) *1969 Sydney Brenner and Ralph Riley *1976 Frederick Sanger *1978 Richard Henderson *1981 César Milstein *1984 John Gurdon *1987 Michael Berridge *1991 Azim Surani *1993 Martin Evans *1995 Nicholas Barry Davies *1998 Tim Clutton-Brock and Andrew Wyllie (shared) *2001 Michael Neuberger and James Cuthbert Smith (shared) *2004 Andrea Brand and Robin Irvine (shared) *2010 Beverley Glover, Dr Peter Forster and Simon Conway Morrisbr>(shared) *2014 Serena Nik-Zainal See also * List of biology awards This list of biology awards is an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Religious Society Of Friends
Quakers are people who belong to a historically Protestant Christian set of Christian denomination, denominations known formally as the Religious Society of Friends. Members of these movements ("theFriends") are generally united by a belief in each human's ability to experience Inward light, the light within or see "that of God in every one". Some profess a priesthood of all believers inspired by the First Epistle of Peter. They include those with evangelicalism, evangelical, Holiness movement, holiness, Mainline Protestant, liberal, and Conservative Friends, traditional Quaker understandings of Christianity. There are also Nontheist Quakers, whose spiritual practice does not rely on the existence of God. To differing extents, the Friends avoid creeds and Hierarchical structure, hierarchical structures. In 2017, there were an estimated 377,557 adult Quakers, 49% of them in Africa. Some 89% of Quakers worldwide belong to ''evangelical'' and ''programmed'' branches that hold ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gloucestershire
Gloucestershire ( abbreviated Glos) is a county in South West England. The county comprises part of the Cotswold Hills, part of the flat fertile valley of the River Severn and the entire Forest of Dean. The county town is the city of Gloucester and other principal towns and villages include Cheltenham, Cirencester, Kingswood, Bradley Stoke, Stroud, Thornbury, Yate, Tewkesbury, Bishop's Cleeve, Churchdown, Brockworth, Winchcombe, Dursley, Cam, Berkeley, Wotton-under-Edge, Tetbury, Moreton-in-Marsh, Fairford, Lechlade, Northleach, Stow-on-the-Wold, Chipping Campden, Bourton-on-the-Water, Stonehouse, Nailsworth, Minchinhampton, Painswick, Winterbourne, Frampton Cotterell, Coleford, Cinderford, Lydney and Rodborough and Cainscross that are within Stroud's urban area. Gloucestershire borders Herefordshire to the north-west, Worcestershire to the north, Warwickshire to the north-east, Oxfordshire to the east, Wiltshire to the south, Bristol and Somerset ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Barry Sharpless
Karl Barry Sharpless (born April 28, 1941) is an American chemist and a two-time Nobel laureate in Chemistry known for his work on stereoselective reactions and click chemistry. Sharpless was awarded half of the 2001 Nobel Prize in Chemistry "for his work on chirally catalysed oxidation reactions", and one third of the 2022 prize, jointly with Carolyn R. Bertozzi and Morten P. Meldal, "for the development of click chemistry and bioorthogonal chemistry". Sharpless is the fifth person (in addition to two organizations), to have twice been awarded a Nobel prize, along with Marie Curie, John Bardeen, Linus Pauling and Frederick Sanger, and the third to have been awarded two prizes in the same discipline (after Bardeen and Sanger). Early life and education Sharpless was born April 28, 1941, in Philadelphia, Pennsylvania. His childhood was filled with summers at his family cottage on the Manasquan River in New Jersey. This is where Sharpless developed a love for fishing that he wo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Bardeen
John Bardeen (; May 23, 1908 – January 30, 1991) was an American physicist and engineer. He is the only person to be awarded the Nobel Prize in Physics twice: first in 1956 with William Shockley and Walter Brattain for the invention of the transistor; and again in 1972 with Leon N. Cooper and John Robert Schrieffer for a fundamental theory of conventional superconductivity known as the BCS theory. The transistor revolutionized the electronics industry, making possible the development of almost every modern electronic device, from telephones to computers, and ushering in the Information Age. Bardeen's developments in superconductivity—for which he was awarded his second Nobel Prize—are used in nuclear magnetic resonance spectroscopy (NMR), medical magnetic resonance imaging (MRI), and superconducting quantum circuits. Born and raised in Wisconsin, Bardeen received a Ph.D. in physics from Princeton University. After serving in World War II, he was a researcher at Bell Lab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paul Berg
Paul Berg (born June 30, 1926) is an American biochemist and professor emeritus at Stanford University. He was the recipient of the Nobel Prize in Chemistry in 1980, along with Walter Gilbert and Frederick Sanger. The award recognized their contributions to basic research involving nucleic acids. Berg received his undergraduate education at Penn State University, where he majored in biochemistry. He received his Ph.D. in biochemistry from Case Western Reserve University in 1952. Berg worked as a professor at Washington University School of Medicine and Stanford University School of Medicine, in addition to serving as the director of the Beckman Center for Molecular and Genetic Medicine. In addition to the Nobel Prize, Berg was presented with the National Medal of Science in 1983 and the National Library of Medicine Medal in 1986. Berg is a member of the Board of Sponsors for the '' Bulletin of the Atomic Scientists''. Early life and education Berg was born in Brooklyn, New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walter Gilbert
Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate. Education and early life Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, the son of Emma (Cohen), a child psychologist, and Richard V. Gilbert, an economist. When Gilbert was seven years old, the family moved to the Washington D.C. area so his father could work under Harry Hopkins on the New Deal brain trust. While living in Washington the family became friends with the family of I.F. Stone and Wally met Stone's oldest daughter, Celia, when they were both 8. They later married at age 21. He was educated at the Sidwell Friends School, and attended Harvard University for undergraduate and graduate studies, earning a baccalaureate in chemistry and physics in 1953 and a master's degree in physics in 1954. He studied for his doctorate at the University of Cambridge, where he earned a PhD in physics supervised by the Nobel laureate Abdus Sal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Dogma Of Molecular Biology
The central dogma of molecular biology is an explanation of the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and RNA makes protein", although this is not its original meaning. It was first stated by Francis Crick in 1957, then published in 1958: He re-stated it in a ''Nature'' paper published in 1970: "The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid." A second version of the central dogma is popular but incorrect. This is the simplistic DNA → RNA → protein pathway published by James Watson in the first edition of ''The Molecular Biology of the Gene'' (1965). Watson's version differs from Crick's because Watson describes a two-step (DNA → RNA and RNA → protein) process as the central dogma. While the dogma, as originally stated by Crick, remains v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
