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Elastofibroma Dorsi
Elastofibroma dorsi is an ill-defined fibroelastic tumor-like condition made up of enlarged and irregular elastic fibers. The World Health Organization, 2020, has classified elastofibroma tumors as one specific type of the fibroblastic and myofibroblastic tumors. Signs and Symptoms Patient will present with a slow growing, deep-seated, firm mass, often presenting bilaterally. There may be pain or tenderness, but this is rare. Cause There are several theories about origin: * There is support for a genetic predisposition, as there are alterations of short arm of chromosome 1; * Multifocality may suggest systemic enzymatic defect, resulting in abnormal elastogenesis; * Repeated trauma or friction seems unlikely, but is still a possibility. Diagnosis By computed tomography, there is a poorly circumscribed, heterogeneous soft tissue mass, with a signal intensity similar to skeletal muscle. The fact that the lesion may be bilateral, helps eliminate a sarcoma from further considerat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elastic Fibers
Elastic fibers (or yellow fibers) are an essential component of the extracellular matrix composed of bundles of proteins (elastin) which are produced by a number of different cell types including fibroblasts, endothelial, smooth muscle, and airway epithelial cells. These fibers are able to stretch many times their length, and snap back to their original length when relaxed without loss of energy. Elastic fibers include elastin, elaunin and oxytalan. Elastic tissue is classified as "connective tissue proper". Elastic fibers are formed via elastogenesis, a highly complex process involving several key proteins including fibulin-4, fibulin-5, latent transforming growth factor β binding protein 4, and microfibril associated protein 4. In this process tropoelastin, the soluble monomeric precursor to elastic fibers is produced by elastogenic cells and chaperoned to the cell surface. Following excretion from the cell, tropoelastin self associates into ~200 nm particles by coace ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibroblastic And Myofibroblastic Tumors
Fibroblastic and myofibroblastic tumors (FMTs) develop from the mesenchymal stem cells which differentiate into fibroblasts (the most common cell type in connective tissue) and/or the myocytes/ myoblasts that differentiate into muscle cells. FMTs are a heterogeneous group of soft tissue neoplasms (i.e. abnormal and excessive tissue growths). The World Health Organization (2020) defined tumors as being FMTs based on their morphology and, more importantly, newly discovered abnormalities in the expression levels of key gene products made by these tumors' neoplastic cells. Histopathologically, FMTs consist of neoplastic connective tissue cells which have differented into cells that have microscopic appearances resembling fibroblasts and/or myofibroblasts. The fibroblastic cells are characterized as spindle-shaped cells with inconspicuous nucleoli that express vimentin, an intracellular protein typically found in mesenchymal cells, and CD34, a cell surface membrane glyc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elastogenesis
Elastic fibers (or yellow fibers) are an essential component of the extracellular matrix composed of bundles of proteins ( elastin) which are produced by a number of different cell types including fibroblasts, endothelial, smooth muscle, and airway epithelial cells. These fibers are able to stretch many times their length, and snap back to their original length when relaxed without loss of energy. Elastic fibers include elastin, elaunin and oxytalan. Elastic tissue is classified as "connective tissue proper". Elastic fibers are formed via elastogenesis, a highly complex process involving several key proteins including fibulin-4, fibulin-5, latent transforming growth factor β binding protein 4, and microfibril associated protein 4. In this process tropoelastin, the soluble monomeric precursor to elastic fibers is produced by elastogenic cells and chaperoned to the cell surface. Following excretion from the cell, tropoelastin self associates into ~200 nm particles by coa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trauma (medicine)
An injury is any physiological damage to living tissue caused by immediate physical stress. An injury can occur intentionally or unintentionally and may be caused by blunt trauma, penetrating trauma, burning, toxic exposure, asphyxiation, or overexertion. Injuries can occur in any part of the body, and different symptoms are associated with different injuries. Treatment of a major injury is typically carried out by a health professional and varies greatly depending on the nature of the injury. Traffic collisions are the most common cause of accidental injury and injury-related death among humans. Injuries are distinct from chronic conditions, psychological trauma, infections, or medical procedures, though injury can be a contributing factor to any of these. Several major health organizations have established systems for the classification and description of human injuries. Occurrence Injuries may be intentional or unintentional. Intentional injuries may be acts of vio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friction
Friction is the force resisting the relative motion of solid surfaces, fluid layers, and material elements sliding against each other. There are several types of friction: *Dry friction is a force that opposes the relative lateral motion of two solid surfaces in contact. Dry friction is subdivided into ''static friction'' ("stiction") between non-moving surfaces, and ''kinetic friction'' between moving surfaces. With the exception of atomic or molecular friction, dry friction generally arises from the interaction of surface features, known as asperities (see Figure 1). *Fluid friction describes the friction between layers of a viscous fluid that are moving relative to each other. *Lubricated friction is a case of fluid friction where a lubricant fluid separates two solid surfaces. *Skin friction is a component of drag, the force resisting the motion of a fluid across the surface of a body. *Internal friction is the force resisting motion between the elements making up a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Ultrasonography
Medical ultrasound includes diagnostic techniques (mainly imaging techniques) using ultrasound, as well as therapeutic applications of ultrasound. In diagnosis, it is used to create an image of internal body structures such as tendons, muscles, joints, blood vessels, and internal organs, to measure some characteristics (e.g. distances and velocities) or to generate an informative audible sound. Its aim is usually to find a source of disease or to exclude pathology. The usage of ultrasound to produce visual images for medicine is called medical ultrasonography or simply sonography. The practice of examining pregnant women using ultrasound is called obstetric ultrasonography, and was an early development of clinical ultrasonography. Ultrasound is composed of sound waves with frequencies which are significantly higher than the range of human hearing (>20,000 Hz). Ultrasonic images, also known as sonograms, are created by sending pulses of ultrasound into tissue usin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hematoxylin And Eosin Stained Photomicrograph Of An Elastofibroma LDRT
Haematoxylin or hematoxylin (), also called natural black 1 or C.I. 75290, is a compound extracted from heartwood of the logwood tree (''Haematoxylum campechianum'') with a chemical formula of . This naturally derived dye has been used as a histologic stain, ink and as a dye in the textile and leather industry. As a dye, haematoxylin has been called Palo de Campeche, logwood extract, bluewood and blackwood. In histology, haematoxylin staining is commonly followed (counterstained), with eosin, when paired, this staining procedure is known as H&E staining, and is one of the most commonly used combinations in histology. In addition to its use in the H&E stain, haematoxylin is also a component of the Papanicolaou stain (or PAP stain) which is widely used in the study of cytology specimens. Although the stain is commonly called ''haematoxylin'', the active colourant is the oxidized form haematein, which forms strongly coloured complexes with certain metal ions (commonly Fe(III) and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pearls
A pearl is a hard, glistening object produced within the soft tissue (specifically the mantle) of a living shelled mollusk or another animal, such as fossil conulariids. Just like the shell of a mollusk, a pearl is composed of calcium carbonate (mainly aragonite or a mixture of aragonite and calcite) in minute crystalline form, which has deposited in concentric layers. The ideal pearl is perfectly round and smooth, but many other shapes, known as baroque pearls, can occur. The finest quality of natural pearls have been highly valued as gemstones and objects of beauty for many centuries. Because of this, ''pearl'' has become a metaphor for something rare, fine, admirable and valuable. The most valuable pearls occur spontaneously in the wild, but are extremely rare. These wild pearls are referred to as ''natural'' pearls. ''Cultured'' or ''farmed'' pearls from pearl oysters and freshwater mussels make up the majority of those currently sold. Imitation pearls are also wide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pipe Cleaner
A pipe cleaner or chenille stem is a type of brush originally intended for removing moisture and residue from smoking pipes. They can also be used for any application that calls for cleaning out small bores or tight places. Special pipe cleaners are manufactured specifically for cleaning out medical apparatus and for engineering applications. Outside of their originally intended purpose, they are commonly used in crafts, and are also popular for winding around bottle necks to catch drips, bundling things together, as a twist tie, colour-coding, and as a makeshift brush for applying paints, oils, solvents, greases, and similar substances. Description Smoking pipe cleaners normally use some absorbent material, usually cotton or sometimes viscose. Bristles of stiffer material, normally monofilament nylon or polypropylene are sometimes added to better scrub out what is being cleaned. Microfilament polyester is used in some technical pipe cleaners because polyester wicks liquid awa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spindle Cell Lipoma
Spindle cell lipoma is an asymptomatic, slow-growing subcutaneous tumor that has a predilection for the posterior back, neck, and shoulders of older men.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. . See also * Intradermal spindle cell lipoma * List of cutaneous conditions References External links Dermal and subcutaneous growths {{Dermal-growth-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuchal Fibroma
Nuchal-type fibroma is a rare benign proliferation involving the dermis and subcutaneous tissues, that is a collection of dense, hypocellular bundles of collagen with entrapped adipocytes and increased numbers of small nerves. It is no longer called a nuchal fibroma, but instead a "nuchal-type fibroma" since it develops in other anatomic sites. There is no known etiology. The World Health Organization, 2020, classified nuchal fibromas as a specific tumor form in the category of benign fibroblastic and myofibroblastic tumors. Signs and symptoms These lesions are generally asymptomatic, although patients give a long history of a solitary, superficial mass. The mass is usually in the neck (hence the name "nuchal-type"), but it can be seen in the extremities, lumbosacral area, buttocks, and face. There is a strong association with diabetes mellitus and Gardner syndrome; in fact, it may be the initial manifestation of Gardner syndrome. Pathology The tumors are unencapsulated and p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
