Carlos Cordon-Cardo
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Carlos Cordon-Cardo
Carlos Cordon-Cardo (born February 25, 1957) is a Spanish-born American physician and scientist known for his research in experimental pathology and molecular oncology. He holds the "Irene Heinz Given and John LaPorte Given" Chair in Pathology at Mount Sinai School of Medicine. Life and career Cordon-Cardo was born in Calella, a seaside town in the Province of Barcelona and was determined to study medicine and pathology from his childhood days when he asked for a microscope for his 10th birthday. He enrolled in the Autonomous University of Barcelona medical school in 1975 and received his MD in 1980. With the encouragement of his mentor at the university and the assistance of a fellowship from the Spanish Government, he then went to Cornell University Medical College for graduate work in pathology, cell biology and genetics.Brody, Jane E. (13 April 1999)"Scientists at Work: Carlos Cordon-Cardo, Cancer Trailblazer Follows the Genetic Fingerprints" ''The New York Times''. Retrieved ...
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Calella
Calella is a municipality in the Maresme region of Spain , image_flag = Bandera de España.svg , image_coat = Escudo de España (mazonado).svg , national_motto = '' Plus ultra'' (Latin)(English: "Further Beyond") , national_anthem = (English: "Royal March") , ..., located 50 km from Barcelona, 50 km from Girona and 6 km from the Montnegre-Corredor Natural Park. It is known as the tourist capital of the Costa del Maresme and is characterized by being a cosmopolitan city with a typical Mediterranean climate. Its urban layout, with a central pedestrian and commercial area, green spaces and wide range accommodation offer, make of Calella an important tourist destination. Calella has beaches three kilometers in length and more than 180,000 m2 of golden sand, blue waters, and natural areas such as Dalmau Park, Manuel Puigvert promenade, Garbí promenade, The Lighthouse or The Turrets. Calella is a city with almost 700 years of history. ...
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Molecular Pathology
Molecular pathology is an emerging discipline within pathology which is focused in the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids. Molecular pathology shares some aspects of practice with both anatomic pathology and clinical pathology, molecular biology, biochemistry, proteomics and genetics, and is sometimes considered a "crossover" discipline. It is multi-disciplinary in nature and focuses mainly on the sub-microscopic aspects of disease. A key consideration is that more accurate diagnosis is possible when the diagnosis is based on both the morphologic changes in tissues (traditional anatomic pathology) and on molecular testing. It is a scientific discipline that encompasses the development of molecular and genetic approaches to the diagnosis and classification of human diseases, the design and validation of predictive biomarkers for treatment response and disease progression, the susceptibility of individuals of ...
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P-glycoprotein
P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi, and bacteria, and it likely evolved as a defense mechanism against harmful substances. P-gp is extensively distributed and expressed in the intestinal epithelium where it pumps xenobiotics (such as toxins or drugs) back into the intestinal lumen, in liver cells where it pumps them into bile ducts, in the cells of the proximal tubule of the kidney where it pumps them into urinary filtrate (in the proximal tubule), and in the capillary endothelial cells composing the blood–brain barrier and blood–testis barrier, where it pumps them back into the capil ...
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Genitourinary System
The genitourinary system, or urogenital system, are the organs of the reproductive system and the urinary system. These are grouped together because of their proximity to each other, their common embryological origin and the use of common pathways, like the male urethra. Also, because of their proximity, the systems are sometimes imaged together. The term "apparatus urogenitalis" was used in ''Nomina Anatomica'' (under Splanchnologia) but is not used in the current '' Terminologia Anatomica''. Development The urinary and reproductive organs are developed from the intermediate mesoderm. The permanent organs of the adult are preceded by a set of structures that are purely embryonic and that, with the exception of the ducts, disappear almost entirely before the end of fetal life. These embryonic structures are on either side: the pronephros, the mesonephros and the metanephros of the kidney, and the Wolffian and Müllerian ducts of the sex organ. The pronephros disappear ...
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Experimental Cancer Treatment
Experimental cancer treatments are mainstream medical therapies intended to treat cancer by improving on, supplementing or replacing conventional methods (surgery, chemotherapy, radiation, and immunotherapy). However, researchers are still trying to determine whether these treatments are safe and effective treatments. Experimental cancer treatments are normally available only to people who participate in formal research programs, which are called ''clinical trials''. Occasionally, a seriously ill person may be able to access an experimental drug through an expanded access program. Some of the treatments have regulatory approval for treating other conditions. Health insurance and publicly funded health care programs normally refuse to pay for experimental cancer treatments. The entries listed below vary between theoretical therapies to unproven controversial therapies. Many of these treatments are alleged to help against only specific forms of cancer. It is not a list of ...
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American Society Of Clinical Oncology
The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide. Physician education ASCO offers educational resources for cancer physicians and other health care professionals of clinical oncology. These include scientific meetings, educational conferences, professional workshops, and special symposia on issues of particular relevance and importance to oncologists and researchers. It also produced the patient information website, Cancer.Net. It publishes numerous journals, books, newsletters, and online and multimedia resources; it publishes the '' Journal of Clinical Oncology'' (JCO), the ''JCO Oncology Practice'' (JCO OP), and the ''JCO Global Oncology'' (JCO GO), ''JCO Clinical Cancer Informatics' ...
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Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ...
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Thomson ISI
The Institute for Scientific Information (ISI) was an academic publishing service, founded by Eugene Garfield in Philadelphia in 1956. ISI offered scientometric and bibliographic database services. Its specialty was citation indexing and analysis, a field pioneered by Garfield. Services ISI maintained citation databases covering thousands of academic journals, including a continuation of its longtime print-based indexing service the Science Citation Index (SCI), as well as the Social Sciences Citation Index (SSCI) and the Arts and Humanities Citation Index (AHCI). All of these were available via ISI's Web of Knowledge database service. This database allows a researcher to identify which articles have been cited most frequently, and who has cited them. The database provides some measure of the academic impact of the papers indexed in it, and may increase their impact by making them more visible and providing them with a quality label. Some anecdotal evidence suggests that appeari ...
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El País
''El País'' (; ) is a Spanish-language daily newspaper in Spain. ''El País'' is based in the capital city of Madrid and it is owned by the Spanish media conglomerate PRISA. It is the second most circulated daily newspaper in Spain . ''El País'' is the most read newspaper in Spanish online and one of the Madrid dailies considered to be a national newspaper of record for Spain (along with '' El Mundo'' and '' ABC)''. In 2018, its number of daily sales were 138,000. Its headquarters and central editorial staff are located in Madrid, although there are regional offices in the principal Spanish cities (Barcelona, Seville, Valencia, Bilbao, and Santiago de Compostela) where regional editions were produced until 2015. ''El País'' also produces a world edition in Madrid that is available online in English and in Spanish (Latin America). History ''El País'' was founded in May 1976 by a team at PRISA which included Jesus de Polanco, José Ortega Spottorno and Carlos Mendo. ...
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Weill Cornell Medical College
The Joan & Sanford I. Weill Medical College of Cornell University is Cornell University's biomedical research unit and medical school located in Upper East Side, Manhattan, New York City, New York. Weill Cornell Medicine is affiliated with NewYork-Presbyterian Hospital, Weill Cornell Medical Center, Hospital for Special Surgery, Memorial Sloan Kettering Cancer Center, and Rockefeller University, all of which are located nearby on York Avenue. Weill Cornell's clinical affiliates rank highly, with the NewYork-Presbyterian Hospital ranked #1 in the region and #4 in the nation, the Hospital for Special Surgery ranked #1 in the nation for orthopedics and the Memorial Sloan Kettering Center #2 for cancer. Memorial Sloan Kettering Cancer Center and Rockefeller University joined Weill Cornell to establish the Tri-Institutional MD–PhD Program in 1991. In 2001, the school opened a campus in Qatar. Weill Cornell has also been affiliated with Houston Methodist Hospital since 2004. ...
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Doctor Honoris Causa
An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad honorem '' ("to the honour"). The degree is typically a doctorate or, less commonly, a master's degree, and may be awarded to someone who has no prior connection with the academic institution or no previous postsecondary education. An example of identifying a recipient of this award is as follows: Doctorate in Business Administration (''Hon. Causa''). The degree is often conferred as a way of honouring a distinguished visitor's contributions to a specific field or to society in general. It is sometimes recommended that such degrees be listed in one's curriculum vitae (CV) as an award, and not in the education section. With regard to the use of this honorific, the policies of institutions of higher education generally ask that recipien ...
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Colon Cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. Risk factors include diet, obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include red meat, processed meat, and alcohol. Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Some of the inherited genetic disorders that can cause colorectal cancer include familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. It typically starts as a benign tumor, often in the form of a polyp, which over time becomes can ...
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