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Baculoviridae
''Baculoviridae'' is a family of viruses. Arthropods, among the most studied being Lepidoptera, Hymenoptera and Diptera, serve as natural hosts. Currently, 85 species are placed in this family, assigned to four genera. Baculoviruses are known to infect insects, with over 600 host species having been described. Immature (larval) forms of lepidopteran species (moths and butterflies) are the most common hosts, but these viruses have also been found infecting sawflies, and mosquitoes. Although baculoviruses are capable of entering mammalian cells in culture, they are not known to be capable of replication in mammalian or other vertebrate animal cells. Starting in the 1940s, they were used and studied widely as biopesticides in crop fields. Baculoviruses contain a circular, double-stranded DNA (dsDNA) genome ranging from 80 to 180 kbp. Historical influence The earliest records of baculoviruses can be found in the literature from as early as the 16th century in reports of "w ...
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Alphabaculovirus
''Alphabaculovirus'' is a genus of viruses in the family ''Baculoviridae''. The natural hosts of species in this family are invertebrates, among them winged insects (Lepidopterans, Hymenopterans, Dipterans), and decapods. However, species in this genus have been isolated only from Lepidoptera. There are 56 species in the genus. Taxonomy The following species are assigned to the genus: * '' Adoxophyes honmai nucleopolyhedrovirus'' * '' Agrotis ipsilon multiple nucleopolyhedrovirus'' * '' Agrotis segetum nucleopolyhedrovirus A'' * '' Agrotis segetum nucleopolyhedrovirus B'' * '' Antheraea pernyi nucleopolyhedrovirus'' * '' Anticarsia gemmatalis multiple nucleopolyhedrovirus'' * ''Autographa californica multiple nucleopolyhedrovirus'' * '' Bombyx mori nucleopolyhedrovirus'' * '' Buzura suppressaria nucleopolyhedrovirus'' * '' Catopsilia pomona nucleopolyhedrovirus'' * '' Choristoneura fumiferana DEF multiple nucleopolyhedrovirus'' * '' Choristoneura fumiferana multiple nucleopolyhe ...
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Gammabaculovirus
''Gammabaculovirus'' is a genus of viruses, in the family ''Baculoviridae''. Hymenoptera serve as natural hosts. There are two species in this genus. Taxonomy The following species are assigned to the genus: *''Neodiprion lecontei nucleopolyhedrovirus'' *''Neodiprion sertifer nucleopolyhedrovirus ''Neodiprion'' is a genus of sawflies in the family Diprionidae. Species * '' Neodiprion abbotii'' * '' Neodiprion abietis'' (Harris) * '' Neodiprion autumnalis'' * '' Neodiprion burkei'' Middleton * '' Neodiprion compar'' * '' Neodiprion d ...'' Structure Viruses in ''Gammabaculovirus'' are enveloped. Genomes are circular, around 82-86kb in length. The genome codes for 90 proteins. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanis ...
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Betabaculovirus
''Betabaculovirus'' is a genus of viruses, in the family ''Baculoviridae''. Arthropods serve as natural hosts. There are 26 species in this genus. Taxonomy The following species are assigned to the genus: * '' Adoxophyes orana granulovirus'' * '' Agrotis segetum granulovirus'' * '' Artogeia rapae granulovirus'' * '' Choristoneura fumiferana granulovirus'' * '' Clostera anachoreta granulovirus'' * '' Clostera anastomosis granulovirus A'' * '' Clostera anastomosis granulovirus B'' * '' Cnaphalocrocis medinalis granulovirus'' * '' Cryptophlebia leucotreta granulovirus'' * ''Cydia pomonella granulovirus'' * '' Diatraea saccharalis granulovirus'' * '' Epinotia aporema granulovirus'' * '' Erinnyis ello granulovirus'' * ''Harrisina brillians granulovirus'' * '' Helicoverpa armigera granulovirus'' * '' Lacanobia oleracea granulovirus'' * '' Mocis latipes granulovirus'' * ''Mythimna unipuncta granulovirus A'' * ''Mythimna unipuncta granulovirus B'' * ''Phthorimaea operculella granuloviru ...
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Deltabaculovirus
''Deltabaculovirus'' is a genus of viruses, in the family ''Baculoviridae ''Baculoviridae'' is a family of viruses. Arthropods, among the most studied being Lepidoptera, Hymenoptera and Diptera, serve as natural hosts. Currently, 85 species are placed in this family, assigned to four genera. Baculoviruses are kn ...''. Mosquito larvae serve as natural hosts. There is only one species in this genus: ''Culex nigripalpus nucleopolyhedrovirus''. Structure Viruses in ''Deltabaculovirus'' are enveloped. Genomes are circular, around 80-180kb in length. The genome codes for 100 to 180 proteins. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export, an ...
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Endosome
Endosomes are a collection of intracellular sorting organelles in eukaryotic cells. They are parts of endocytic membrane transport pathway originating from the trans Golgi network. Molecules or ligands internalized from the plasma membrane can follow this pathway all the way to lysosomes for degradation or can be recycled back to the cell membrane in the endocytic cycle. Molecules are also transported to endosomes from the trans Golgi network and either continue to lysosomes or recycle back to the Golgi apparatus. Endosomes can be classified as early, sorting, or late depending on their stage post internalization. Endosomes represent a major sorting compartment of the endomembrane system in cells. Function Endosomes provide an environment for material to be sorted before it reaches the degradative lysosome. For example, low-density lipoprotein (LDL) is taken into the cell by binding to the LDL receptor at the cell surface. Upon reaching early endosomes, the LDL dissociates ...
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Cell Membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of cells and organelles, being selectively permeable to i ...
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Epithelial Cell
Epithelium or epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. It is a thin, continuous, protective layer of compactly packed cells with a little intercellular matrix. Epithelial tissues line the outer surfaces of organs and blood vessels throughout the body, as well as the inner surfaces of cavities in many internal organs. An example is the epidermis, the outermost layer of the skin. There are three principal shapes of epithelial cell: squamous (scaly), columnar, and cuboidal. These can be arranged in a singular layer of cells as simple epithelium, either squamous, columnar, or cuboidal, or in layers of two or more cells deep as stratified (layered), or ''compound'', either squamous, columnar or cuboidal. In some tissues, a layer of columnar cells may appear to be stratified due to the placement of the nuclei. This sort of tissue is called pseudostratified. All glands are made up of epith ...
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Shrimp
Shrimp are crustaceans (a form of shellfish) with elongated bodies and a primarily swimming mode of locomotion – most commonly Caridea and Dendrobranchiata of the decapod order, although some crustaceans outside of this order are referred to as "shrimp". More narrow definitions may be restricted to Caridea, to smaller species of either group or to only the marine species. Under a broader definition, ''shrimp'' may be synonymous with prawn, covering stalk-eyed swimming crustaceans with long, narrow muscular tails ( abdomens), long whiskers ( antennae), and slender legs. Any small crustacean which resembles a shrimp tends to be called one. They swim forward by paddling with swimmerets on the underside of their abdomens, although their escape response is typically repeated flicks with the tail driving them backwards very quickly. Crabs and lobsters have strong walking legs, whereas shrimp have thin, fragile legs which they use primarily for perching.Rudloe & Rudloe ...
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Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment ( pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be gr ...
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Secondary Infection
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune system. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Infectious diseases resulted in 9.2 million deaths in 2013 (about 17% of all deaths). The branch of medicine that focuses on infections is referred to as infectious disease. Types Infections are caused by infectious agents (pathogens) including: * Bacteria (e.g. ''Mycobacterium tuberculosis' ...
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H5N1
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus which can cause illness in humans and many other animal species. A bird-adapted strain of H5N1, called HPAI A(H5N1) for highly pathogenic avian influenza virus of type A of subtype H5N1, is the highly pathogenic causative agent of H5N1 flu, commonly known as avian influenza ("bird flu"). It is enzootic (maintained in the population) in many bird populations, especially in Southeast Asia. One strain of HPAI A(H5N1) is spreading globally after first appearing in Asia. It is epizootic (an epidemic in nonhumans) and panzootic (affecting animals of many species, especially over a wide area), killing tens of millions of birds and spurring the culling of hundreds of millions of others to stem its spread. Many references to "bird flu" and H5N1 in the popular media refer to this strain. This was reprinted in 2005: According to the World Health Organization (WHO) and the United Nations Food and Agriculture ...
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