remission (medicine)
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Remission is either the reduction or disappearance of the
signs and symptoms Signs and symptoms are diagnostic indications of an illness, injury, or condition. Signs are objective and externally observable; symptoms are a person's reported subjective experiences. A sign for example may be a higher or lower temperature ...
of a
disease A disease is a particular abnormal condition that adversely affects the structure or function (biology), function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical condi ...
. The term may also be used to refer to the period during which this reduction occurs. A remission may be considered a partial remission or a complete remission. Each disease, type of disorder, or
clinical trial Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel v ...
can have its own definition of a partial remission. For example, a partial remission for
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
may be defined as a 50% or greater reduction in the measurable parameters of tumor growth as may be found on physical examination, radiologic study, or by biomarker levels from a blood or urine test. A complete remission, also called a full remission, is a total disappearance of the signs and symptoms of a disease. A person whose condition is in complete remission may be considered
cure A cure is a substance or procedure that resolves a medical condition. This may include a medication, a surgery, surgical operation, a lifestyle change, or even a philosophical shift that alleviates a person's suffering or achieves a state of heali ...
d or recovered. Relapse is a term to describe returning symptoms of the disease after a period of remission. In cancer-treatment, doctors usually avoid the term "cured" and instead prefer the term "no evidence of disease" (NED) to refer to a complete remission of cancer, which does not rule out the possibility of relapse. In
mental disorder A mental disorder, also referred to as a mental illness, a mental health condition, or a psychiatric disability, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. A mental disorder is ...
s, there is generally no distinction between partial remission and complete remission. For example, a person diagnosed with a personality disorder must initially fit a set or subset of criteria from a predefined list, and remission in this context is defined as no longer meeting the criteria required for diagnosis. In this case it is still possible for the person to be demonstrating some symptoms, but they are at a subclinical severity or frequency that does not merit re-diagnosis. For some diseases featuring remission, especially for those with no known cure such as
multiple sclerosis Multiple sclerosis (MS) is an autoimmune disease resulting in damage to myelinthe insulating covers of nerve cellsin the brain and spinal cord. As a demyelinating disease, MS disrupts the nervous system's ability to Action potential, transmit ...
, remission is implied to always be partial.


See also

* Relapsing-remitting * Spontaneous remission


References

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