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Replacement arthroplasty (from Greek ''arthron'', joint, limb, articulate, + ''plassein'', to form, mould, forge, feign, make an image of), or joint replacement surgery, is a procedure of
orthopedic surgery Orthopedic surgery or orthopedics ( alternatively spelt orthopaedics), is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgical and nonsurgical means to treat musculoskeletal ...
in which an arthritic or dysfunctional joint surface is replaced with an orthopedic
prosthesis In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
. Joint replacement is considered as a treatment when severe joint pain or dysfunction is not alleviated by less-invasive therapies. It is a form of arthroplasty, and is often indicated from various
joint diseases An arthropathy is a disease of a joint. Types Arthritis is a form of arthropathy that involves inflammation of one or more joints, while the term arthropathy may be used regardless of whether there is inflammation or not. Joint diseases can be ...
, including
osteoarthritis Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the ...
and
rheumatoid arthritis Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are inv ...
. Joint replacement surgery has become more common, with knees and hips replaced most often. About 773,000 Americans had a hip or knee replaced in 2009.Joint Replacement Surgery and You. (April, 2009) In ''Arthritis, Musculoskeletal and Skin Disease online''. Retrieved from http://www.niams.nih.gov/#.


Uses


Shoulder

For
shoulder replacement Shoulder replacement is a surgical procedure in which all or part of the glenohumeral joint is replaced by a prosthetic implant. Such joint replacement surgery generally is conducted to relieve arthritis pain or fix severe physical joint damage. ...
, there are a few major approaches to access the shoulder joint. The first is the deltopectoral approach, which saves the deltoid, but requires the supraspinatus to be cut. The second is the transdeltoid approach, which provides a straight on approach at the glenoid. However, during this approach the deltoid is put at risk for potential damage. Both techniques are used, depending on the surgeon's preferences. The number of shoulder replacements carried out each year is increasing, but research looking into global records suggests that nine out of ten shoulder replacements last for at least a decade.


Hip

Hip replacement Hip replacement is a surgical procedure in which the hip joint is replaced by a prosthetic implant, that is, a hip prosthesis. Hip replacement surgery can be performed as a total replacement or a hemi (half) replacement. Such joint replacement o ...
can be performed as a total replacement or a hemi (half) replacement. A total hip replacement consists of replacing both the
acetabulum The acetabulum (), also called the cotyloid cavity, is a concave surface of the pelvis. The head of the femur meets with the pelvis at the acetabulum, forming the hip joint. Structure There are three bones of the ''os coxae'' (hip bone) that c ...
and the femoral head while hemiarthroplasty generally only replaces the femoral head. Hip replacement is currently the most common orthopaedic operation, though patient satisfaction short- and long-term varies widely. It is unclear whether the use of assistive equipment would help in post-operative care.


Knee

Knee replacement involves exposure of the front of the knee, with detachment of part of the quadriceps muscle ( vastus medialis) from the
patella The patella, also known as the kneecap, is a flat, rounded triangular bone which articulates with the femur (thigh bone) and covers and protects the anterior articular surface of the knee joint. The patella is found in many tetrapods, such as ...
. The
patella The patella, also known as the kneecap, is a flat, rounded triangular bone which articulates with the femur (thigh bone) and covers and protects the anterior articular surface of the knee joint. The patella is found in many tetrapods, such as ...
is displaced to one side of the joint, allowing exposure of the
distal Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position pro ...
end of the
femur The femur (; ), or thigh bone, is the proximal bone of the hindlimb in tetrapod vertebrates. The head of the femur articulates with the acetabulum in the pelvic bone forming the hip joint, while the distal part of the femur articulates ...
and the
proximal Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position ...
end of the
tibia The tibia (; ), also known as the shinbone or shankbone, is the larger, stronger, and anterior (frontal) of the two bones in the leg below the knee in vertebrates (the other being the fibula, behind and to the outside of the tibia); it conn ...
. The ends of these bones are then accurately cut to shape using cutting guides oriented to the long axis of the bones. The
cartilage Cartilage is a resilient and smooth type of connective tissue. In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, and is a structural component of many body parts including the rib cage, the neck ...
s and the
anterior cruciate ligament The anterior cruciate ligament (ACL) is one of a pair of cruciate ligaments (the other being the posterior cruciate ligament) in the human knee. The two ligaments are also called "cruciform" ligaments, as they are arranged in a crossed formati ...
are removed; the posterior cruciate ligament may also be removed but the tibial and
fibular The fibula or calf bone is a leg bone on the lateral side of the tibia, to which it is connected above and below. It is the smaller of the two bones and, in proportion to its length, the most slender of all the long bones. Its upper extremity ...
collateral ligaments are preserved. Metal components are then impacted onto the bone or fixed using polymethylmethacrylate (PMMA) cement. Alternative techniques exist that affix the implant without cement. These cement-less techniques may involve osseointegration, including porous metal prostheses. The operation typically involves substantial postoperative pain, and includes vigorous physical rehabilitation. The recovery period may be 6 weeks or longer and may involve the use of mobility aids (e.g. walking frames, canes, crutches) to enable the person's return to preoperative mobility.


Ankle

Ankle replacement has become a treatment of choice for people requiring arthroplasty, replacing the conventional use of arthrodesis, i.e. fusion of the bones. The restoration of range of motion is the key feature in favor of ankle replacement with respect to arthrodesis. However, clinical evidence of the superiority of the former has only been demonstrated for particular isolated implant designs.


Finger

Finger joint replacement is a relatively quick procedure of about 30 minutes, but requires several months of subsequent therapy. Post-operative therapy may consist of wearing a hand splint or performing exercises to improve function and pain.


Risks and complications


Medical risks

The Stress of the operation may result in medical problems of varying incidence and severity. *
Heart Attack A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to the coronary artery of the heart, causing damage to the heart muscle. The most common symptom is chest pain or discomfort which ma ...
*
Stroke A stroke is a disease, medical condition in which poor cerebral circulation, blood flow to the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemorr ...
*
Venous Thromboembolism Venous thrombosis is blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off (embolizes) and flows to the lungs to ...
*
Pneumonia Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severit ...
* Increased confusion *
Urinary Tract Infection A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidne ...
(UTI)


Intra-operative risks

* Mal-positioning of the components ** Shortening; ** Instability/dislocation; ** Loss of range of motion; *
Fracture Fracture is the separation of an object or material into two or more pieces under the action of stress. The fracture of a solid usually occurs due to the development of certain displacement discontinuity surfaces within the solid. If a displ ...
of the adjacent bone; * Nerve damage; * Damage to blood vessels.


Immediate risks

*
Infection An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable di ...
, either Superficial or Deep *
Dislocation In materials science, a dislocation or Taylor's dislocation is a linear crystallographic defect or irregularity within a crystal structure that contains an abrupt change in the arrangement of atoms. The movement of dislocations allow atoms to s ...


Medium-term risks

*
Dislocation In materials science, a dislocation or Taylor's dislocation is a linear crystallographic defect or irregularity within a crystal structure that contains an abrupt change in the arrangement of atoms. The movement of dislocations allow atoms to s ...
* Persistent pain; * Loss of range of motion; * Weakness; * Indolent
infection An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable di ...
.


Long-term risks

* Loosening of the components: the bond between the bone and the components or the cement may break down or fatigue. As a result, the component moves inside the bone, causing pain. Fragments of wear debris may cause an inflammatory reaction with bone absorption which can cause loosening. This phenomenon is known as
osteolysis Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification. Although osteoclasts are active during the natural formation of healthy bone the term "osteolysis" specifically refers to a pa ...
. * Polyethylene synovitis - Wear of the
weight-bearing In orthopedics, weight-bearing is the amount of weight In science and engineering, the weight of an object is the force acting on the object due to gravity. Some standard textbooks define weight as a vector quantity, the gravitational force acti ...
surfaces: polyethylene is thought to wear in
weight-bearing In orthopedics, weight-bearing is the amount of weight In science and engineering, the weight of an object is the force acting on the object due to gravity. Some standard textbooks define weight as a vector quantity, the gravitational force acti ...
joints such as the hip at a rate of 0.3mm per year. This may be a problem in itself since the bearing surfaces are often less than 10 mm thick and may deform as they get thinner. The wear may also cause problems, as inflammation can be caused by increased quantities of polyethylene wear particles in the
synovial fluid Synovial fluid, also called synovia, elp 1/sup> is a viscous, non-Newtonian fluid found in the cavities of synovial joints. With its egg white–like consistency, the principal role of synovial fluid is to reduce friction between the articul ...
. There are many controversies. Much of the research effort of the orthopedic-community is directed to studying and improving joint replacement. The main controversies are * the best or most appropriate bearing surface - metal/polyethylene, metal-metal, ceramic-ceramic; * cemented vs uncemented fixation of the components; * Minimally invasive surgery.


Technique

Before major surgery is performed, a complete pre-anaesthetic work-up is required. In elderly people this usually would include ECG, urine tests, hematology and blood tests. Cross match of blood is routine also, as a high percentage of people receive a blood transfusion. Pre-operative planning requires accurate Xrays of the affected joint, implant design selecting and size-matching to the xray images (a process known as templating). A few days' hospitalization is followed by several weeks of protected function, healing and rehabilitation. This may then be followed by several months of slow improvement in strength and endurance. Early mobilisation of the person is thought to be the key to reducing the chances of complications such as
venous thromboembolism Venous thrombosis is blockage of a vein caused by a thrombus (blood clot). A common form of venous thrombosis is deep vein thrombosis (DVT), when a blood clot forms in the deep veins. If a thrombus breaks off (embolizes) and flows to the lungs to ...
and
Pneumonia Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severit ...
. Modern practice is to mobilize people as soon as possible and ambulate with walking aids when tolerated. Depending on the joint involved and the pre-op status of the person, the time of hospitalization varies from 1 day to 2 weeks, with the average being 4–7 days in most regions.
Physiotherapy Physical therapy (PT), also known as physiotherapy, is one of the allied health professions. It is provided by physical therapists who promote, maintain, or restore health through physical examination, diagnosis, management, prognosis, patie ...
is used extensively to help people recover function after joint replacement surgery. A graded exercise programme is needed initially, as the person's muscles take time to heal after the surgery; exercises for range of motion of the joints and ambulation should not be strenuous. Later when the muscles have healed, the aim of exercise expands to include strengthening and recovery of function.


Materials

Some ceramic materials commonly used in joint replacement are alumina (Al2O3), zirconia (ZrO2), silica (SiO2), hydroxyapatite (Ca10(PO4)6(OH)2), titanium nitride (TiN), silicon nitride (Si3N4). A combination of titanium and titanium carbide is a very hard ceramic material often used in components of arthroplasties due to the impressive degree of strength and toughness it presents, as well as its compatibility with medical imaging. Titanium carbide has proved to be possible to use combined with sintered polycrystalline diamond surface (PCD), a superhard ceramic which promises to provide an improved, strong, long-wearing material for artificial joints. PCD is formed from polycrystalline diamond compact (PDC) through a process involving high pressures and temperatures. When compared with other ceramic materials such as cubic boron nitride, silicon nitride, and aluminum oxide, PCD shows many better characteristics, including a high level of hardness and a relatively low coefficient of friction. For the application of artificial joints it will likely be combined with certain metals and metal alloys like cobalt, chrome, titanium, vanadium, stainless steel, aluminum, nickel, hafnium, silicon, cobalt-chrome, tungsten, zirconium, etc. This means that people with nickel allergy or sensitivities to other metals are at risk for complications due to the chemicals in the device. In knee replacements there are two parts that are ceramic and they can be made of either the same ceramic or different ones. If they are made of the same ceramic, however, they have different weight ratios. These ceramic parts are configured so that should shards break off of the implant, the particles are benign and not sharp. They are also made so that if a shard were to break off of one of the two ceramic components, they would be noticeable through x-rays during a check-up or inspection of the implant. With implants such as hip implants, the ball of the implant could be made of ceramic, and between the ceramic layer and where it attaches to the rest of the implant, there is usually a membrane to help hold the ceramic. The membrane can help prevent cracks, but if cracks should occur at two points which create a separate piece, the membrane can hold the shard in place so that it doesn't leave the implant and cause further injury. Because these cracks and separations can occur, the material of the membrane is a bio-compatible polymer that has a high fracture toughness and a high shear toughness.Monaghan, Matthew, David Miller. (2013). US Patent No. 0282134A1. Warsaw, IN: U
http://worldwide.espacenet.com/
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Prosthesis replacement

The prosthesis may need to be replaced due to complications such as infection or prosthetic fracture. Replacement may be done in one single surgical session. Alternatively, an initial surgery may be performed to remove previous prosthetic material, and the new prosthesis is then inserted in a separate surgery at a later time. In such cases, especially when complicated by infection, a ''spacer'' may be used, which is a sturdy mass to provide some basic joint stability and mobility until a more permanent prosthesis is inserted. It can contain
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention ...
s to help treating any infection.


History

Stephen S. Hudack, a surgeon based in New York City, began
animal testing Animal testing, also known as animal experimentation, animal research, and ''in vivo'' testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study. This ...
with artificial joints in 1939. By 1948, he was at the New York Orthopedic Hospital (part of the
Columbia Presbyterian Medical Center The NewYork-Presbyterian Hospital is a nonprofit academic medical center in New York City affiliated with two Ivy League medical schools, Cornell University and Columbia University. The hospital comprises seven distinct campuses located in the New ...
) and with funding from the Office of Naval Research, was replacing hip joints in humans. Two previously popular forms of arthroplasty were: (1) ''interpositional arthroplasty, with interposition of some other tissue like
skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different ...
,
muscle Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of mus ...
or
tendon A tendon or sinew is a tough, high-tensile-strength band of dense fibrous connective tissue that connects muscle to bone. It is able to transmit the mechanical forces of muscle contraction to the skeletal system without sacrificing its ability ...
to keep inflammatory surfaces apart and (2) ''excisional arthroplasty'' in which the joint surface and bone were removed leaving
scar A scar (or scar tissue) is an area of fibrous tissue that replaces normal skin after an injury. Scars result from the biological process of wound repair in the skin, as well as in other organs, and tissues of the body. Thus, scarring is a ...
tissue to fill in the gap. Other forms of arthroplasty include ''resection(al) arthroplasty'', ''resurfacing arthroplasty'', ''mold arthroplasty'', ''cup arthroplasty'', and ''silicone replacement arthroplasty''. Osteotomy to restore or modify joint congruity is also a form of arthroplasty. In recent decades, the most successful and common form of arthroplasty is the surgical replacement of a joint or joint surface with a
prosthesis In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
. For example, a hip joint that is affected by osteoarthritis may be replaced entirely (
total hip arthroplasty Hip replacement is a surgical procedure in which the hip joint is replaced by a prosthetic implant, that is, a hip prosthesis. Hip replacement surgery can be performed as a total replacement or a hemi (half) replacement. Such joint replacement ...
) with a prosthetic hip. This procedure involves replacing both the acetabulum (hip socket) and the head and neck of the
femur The femur (; ), or thigh bone, is the proximal bone of the hindlimb in tetrapod vertebrates. The head of the femur articulates with the acetabulum in the pelvic bone forming the hip joint, while the distal part of the femur articulates ...
. The purpose of doing this surgery is to relieve pain, to restore range of motion and to improve walking ability, leading to the improvement of muscle strength.


See also

*
Rheumasurgery Rheumatology (Greek ''ῥεῦμα'', ''rheûma'', flowing current) is a branch of medicine devoted to the diagnosis and management of disorders whose common feature is inflammation in the bones, muscles, joints, and internal organs. Rheumatolog ...
* Arthroplasty *
Orthopedic surgery Orthopedic surgery or orthopedics ( alternatively spelt orthopaedics), is the branch of surgery concerned with conditions involving the musculoskeletal system. Orthopedic surgeons use both surgical and nonsurgical means to treat musculoskeletal ...
* Joint replacement registry


Related treatments

*
Autologous chondrocyte implantation Autologous chondrocyte implantation (ACI, ATC code ) is a biomedical treatment that repairs damages in articular cartilage. ACI provides pain relief while at the same time slowing down the progression or considerably delaying partial or total joi ...
*
Microfracture surgery Fracture mechanics is the field of mechanics concerned with the study of the propagation of cracks in materials. It uses methods of analytical solid mechanics to calculate the driving force on a crack and those of experimental solid mechanics t ...


References


External links


Patient Information from the American Academy of Orthopedic Surgeons



P. Benum; A. Aamodt; and K. Haugan ''Uncementeed Custom Femoral Components In Hip Arthroplasty''
* {{DEFAULTSORT:Joint Replacement Implants (medicine) Prosthetics Orthopedic surgical procedures Orthopedic implants