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The internal urethral sphincter is a urethral sphincter muscle which constricts the
internal urethral orifice The internal urethral orifice is the opening of the urinary bladder into the urethra. It is placed at the apex of the trigonum vesicae, in the most dependent part of the bladder, and is usually somewhat crescent-shaped; the mucous membrane immedi ...
. It is located at the junction of the
urethra The urethra (from Greek οὐρήθρα – ''ourḗthrā'') is a tube that connects the urinary bladder to the urinary meatus for the removal of urine from the body of both females and males. In human females and other primates, the urethra ...
with the
urinary bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine ente ...
and is continuous with the detrusor muscle, but anatomically and functionally fully independent from it., page 29
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It is composed of
smooth muscle Smooth muscle is an involuntary non- striated muscle, so-called because it has no sarcomeres and therefore no striations (''bands'' or ''stripes''). It is divided into two subgroups, single-unit and multiunit smooth muscle. Within single-unit ...
, so it is under the control of the
autonomic nervous system The autonomic nervous system (ANS), formerly referred to as the vegetative nervous system, is a division of the peripheral nervous system that supplies internal organs, smooth muscle and glands. The autonomic nervous system is a control system t ...
, specifically the
sympathetic nervous system The sympathetic nervous system (SNS) is one of the three divisions of the autonomic nervous system, the others being the parasympathetic nervous system and the enteric nervous system. The enteric nervous system is sometimes considered part of t ...
.


Function

This is the primary muscle for maintaining continence of
urine Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excreted from the body through the urethra. Cellul ...
, a function shared with the external urethral sphincter which is under voluntary control. It prevents urine leakage as the muscle is tonically contracted via sympathetic fibers traveling through the
inferior hypogastric plexus The inferior hypogastric plexus (pelvic plexus in some texts) is a network () of nerves that supplies the organs of the pelvic cavity. The inferior hypogastric plexus gives rise to the prostatic plexus in males and the uterovaginal plexus in femal ...
and vesical nervous plexus. Specifically, it is controlled by the hypogastric nerve, predominantly via the alpha-1 receptor. During urination, the preganglionic neurons of this sympathetic pathway are inhibited via signals arising in the pontine micturition center and traveling through the descending reticulospinal tracts, allowing the muscle to relax. During
ejaculation Ejaculation is the discharge of semen (the ''ejaculate''; normally containing sperm) from the male reproductory tract as a result of an orgasm. It is the final stage and natural objective of male sexual stimulation, and an essential compo ...
, the muscle contracts to prevent reflux of
semen Semen, also known as seminal fluid, is an organic bodily fluid created to contain spermatozoa. It is secreted by the gonads (sexual glands) and other sexual organs of male or hermaphroditic animals and can fertilize the female ovum. Sem ...
into the
urinary bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine ente ...
, a phenomenon called retrograde ejaculation. Spasms of the internal urethral sphincter are associated with penile erection. Because the internal urethral sphincter is under involuntary control, it is believed to play a role in paruresis, in which a person who perceives oneself to be under observation is unable to urinate.


See also

* Detrusor muscle *
External sphincter muscle of female urethra The external sphincter muscle of female urethra is a muscle which controls urination in females. The muscle fibers arise on either side from the margin of the inferior ramus of the pubis. They are directed across the pubic arch in front of the ure ...
*
External sphincter muscle of male urethra The external sphincter muscle of male urethra, also sphincter urethrae membranaceae, sphincter urethrae externus, surrounds the whole length of the membranous urethra, and is enclosed in the fascia of the urogenital diaphragm. Its external fiber ...
* Urination#Physiology


References

{{Authority control Urinary system Urethra