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Intense pulsed light (IPL) is a technology used by cosmetic and medical practitioners to perform various skin treatments for aesthetic and therapeutic purposes, including
hair removal Hair removal, also known as epilation or depilation, is the deliberate removal of body hair or head hair. Hair typically grows all over the human body and can vary in thickness and length across human populations. Hair can become more visible d ...
, photorejuvenation (e.g. the treatment of skin pigmentation, sun damage, and thread veins) as well as to alleviate dermatologic diseases such as acne. IPL is increasingly used in optometry and ophthalmology as well, to treat evaporative dry eye disease due to
meibomian gland Meibomian glands (also called tarsal glands, palpebral glands, and tarsoconjunctival glands) are sebaceous glands along the rims of the eyelid inside the tarsal plate. They produce meibum, an oily substance that prevents evaporation of the eye ...
dysfunction. The technology uses a high-powered, hand-held, computer-controlled flashgun to deliver an intense, visible, broad-spectrum pulse of light, generally in the visible spectral range of 400 to 1200 nm. Various cutoff filters are commonly used to selectively filter out shorter wavelengths, especially potentially damaging ultra violet light. The resulting light has a spectral range that targets specific structures and chromophores (e.g. melanin in hair, or oxyhemoglobin in blood vessels) that are heated to destruction and reabsorbed by the body. IPL shares some similarities with laser treatments, in that they both use light to heat and destroy their targets. But unlike lasers that use a single wavelength (color) of light which typically matches only one chromophore and hence only treats one condition, IPL uses a broad spectrum that when used with interchangeable filters, allowing it to be used against several conditions. This can be achieved when the IPL technician selects the appropriate filter that matches a specific chromophore.


Description

''Intense pulsed light'' is the use of intense
pulses In medicine, a pulse represents the tactile arterial palpation of the cardiac cycle (heartbeat) by trained fingertips. The pulse may be palpated in any place that allows an artery to be compressed near the surface of the body, such as at the nec ...
of non-
coherent light In physics, two wave sources are coherent if their frequency and waveform are identical. Coherence is an ideal property of waves that enables stationary (i.e., temporally or spatially constant) interference. It contains several distinct concepts, ...
over a range of
wavelength In physics, the wavelength is the spatial period of a periodic wave—the distance over which the wave's shape repeats. It is the distance between consecutive corresponding points of the same phase on the wave, such as two adjacent crests, tr ...
s from 500 nm to 1200 nm.
Xenon Xenon is a chemical element with the symbol Xe and atomic number 54. It is a dense, colorless, odorless noble gas found in Earth's atmosphere in trace amounts. Although generally unreactive, it can undergo a few chemical reactions such as the ...
flashlamps produce high output bursts of broad spectrum. Cooling is used to protect the skin in contact with the device. Regulations governing IPL vary by jurisdiction. A distinction is sometimes made between beauty-grade and medical-grade machines, mainly to get around regulations. The first FDA approval of IPL was for
telangiectasias Telangiectasias, also known as spider veins, are small dilated blood vessels that can occur near the surface of the skin or mucous membranes, measuring between 0.5 and 1 millimeter in diameter. These dilated blood vessels can develop anywhere on ...
in 1995. Use quickly spread to a variety of medical and cosmetic settings. Treatment is generally safe and effective, but complications can occur, such as
hyperpigmentation Hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin. Causes Hyperpigmentation can be caused by sun damage, inflammation, or other skin injuries, including those related to acne vulgaris.James, William; Be ...
. The polychromatic light can reach multiple chromophores in human skin: mainly
hemoglobin Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythroc ...
, water, and
melanin Melanin (; from el, μέλας, melas, black, dark) is a broad term for a group of natural pigments found in most organisms. Eumelanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino ...
. This results in selective photothermolysis of
blood vessels The blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away f ...
, pigmented cells, or
hair follicle The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ...
s.


Hair removal

IPL can reduce hair growth, most effectively in darker, coarser hair. IPL should not be confused with
laser hair removal Laser hair removal is the process of hair removal by means of exposure to pulses of laser light that destroy the hair follicle. It had been performed experimentally for about twenty years before becoming commercially available in 1995 and 1996. ...
, a different procedure using coherent,
monochromatic A monochrome or monochromatic image, object or palette is composed of one color (or values of one color). Images using only shades of grey are called grayscale (typically digital) or black-and-white (typically analog). In physics, monochro ...
laser light.


Protocol

Broad-
spectrum A spectrum (plural ''spectra'' or ''spectrums'') is a condition that is not limited to a specific set of values but can vary, without gaps, across a continuum. The word was first used scientifically in optics to describe the rainbow of colors ...
light Light or visible light is electromagnetic radiation that can be perceived by the human eye. Visible light is usually defined as having wavelengths in the range of 400–700 nanometres (nm), corresponding to frequencies of 750–420 t ...
is applied to the surface of the
skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different ...
, targeting melanin. This light travels through the skin until it strikes the
hair Hair is a protein filament that grows from follicles found in the dermis. Hair is one of the defining characteristics of mammals. The human body, apart from areas of glabrous skin, is covered in follicles which produce thick terminal and fi ...
shafts or
hair follicle The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between ...
. The follicle is usually where the highest concentration of
melanin Melanin (; from el, μέλας, melas, black, dark) is a broad term for a group of natural pigments found in most organisms. Eumelanin is produced through a multistage chemical process known as melanogenesis, where the oxidation of the amino ...
is located. As the light is absorbed, the bulb and most of the hair shaft are heated, destroying the hair-producing papilla. It is also claimed that heat conversion occurs directly in the darker capillaries that bring blood to the follicle. At any one time, not all hair follicles are ‘active’, and only active hair follicles can be affected by the treatment. ‘Inactive’ hair follicles can be treated as they become ‘active’ over time. For IPL treatments, an average of 8–10 treatments, 4–6 weeks apart, are required to remove most visible hair. There is no common treatment protocol, as it depends on the equipment used and patient skin type. The area to be treated should be clean shaven and free of sunburn. Although IPL treatments will permanently reduce the total number of body hairs, they will not result in a permanent removal of all hair. Certain skin conditions, health irregularities, and medications can impact whether it is safe for a person to receive a light-based hair removal treatment. Photo-sensitizing medications, or damage to the skin are contraindications to treatment. According to Remington, manufacturer of an IPL device, all IPL and laser devices should only be used on light to medium skin tones, and work best on darker hair.


Efficacy

In August 1997, IPL was reported to have permanently removed terminal hair in two patients who underwent multiple treatments to their beards. In October of that year, the first IPL system developed for hair removal and resulted in 60% hair reduction after 12 weeks. It is important to note that these studies utilized a variety of IPL devices on patients with various hair types, skin types, and targeted skin areas. Thus the results are not directly comparable. According to the FDA, permanent hair removal means the "long-term, stable reduction in the number of hairs regrowing after a treatment regime." In other words, the number of hairs regrowing must be consistently greater than the duration of the complete growth cycle of hair follicles, which varies from four to twelve months by body location. IPL has been found to be much less effective than laser hair removal; however, many patients experience satisfaction with significant hair reduction. A 2006 article in the journal ''
Lasers in Medical Science ''Lasers in Medical Science'' is a bimonthly peer-reviewed medical journal covering laser medicine. It was established in 1986 and is published by Springer Science+Business Media. It is the official journal of Sociedad Española de Láser Médic ...
'' compared IPL and both alexandrite and diode lasers. The review found no statistical difference in effectiveness, but a higher incidence of side effects with diode laser treatment. Hair reduction after 6 months was reported as 68.75% for alexandrite lasers, 71.71% for diode lasers, and 66.96% for IPL. Side effects were reported as 9.5% for alexandrite lasers, 28.9% for diode lasers, and 15.3% for IPL. All side effects were found to be temporary and even pigmentation changes returned to normal within 6 months. A 2009 study evaluated the rate of hair removal after a second generation IPL source. Results found that patients had 75% hair reduction after 4 months, and up to 80% after 8 months.


Medical use

IPL was first developed for vascular conditions. It is at least as effective as pulsed dye lasers and can penetrate deeper with reduced risk of purpura and hyperpigmentation. IPL can also be used for the treatment of dry eye conditions such as meibomian gland dysfunction. IPL can treat pigmented lesions with rapid recovery. Dyschromia can be cleared after repeated sessions. Photoaging treatment has been explored. A series of IPL can be used for facial rejuvenation, improving skin laxity and collagen production. IPL combined with facial injections can be used for dynamic rhytids. Home IPL devices have been developed. IPL is employed in the treatment of a range of dermatological conditions including photodamage induced dyspigmentation and vascular changes, poikiloderma of Civatte,
rosacea Rosacea is a long-term skin condition that typically affects the face. It results in redness, pimples, swelling, and small and superficial dilated blood vessels. Often, the nose, cheeks, forehead, and chin are most involved. A red, enlarg ...
,
acne vulgaris Acne, also known as ''acne vulgaris'', is a long-term skin condition that occurs when dead skin cells and oil from the skin clog hair follicles. Typical features of the condition include blackheads or whiteheads, pimples, oily skin, and po ...
, sebaceous gland hyperplasia, broken capillaries, telangiectases, vascular lesions (small blood vessels), pigmented lesions (freckles, liver spots, birth marks ), melasma,
actinic keratosis Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, is a pre-cancerous area of thick, scaly, or crusty skin.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. . Actinic k ...
, photorejuvenation, basal cell carcinoma, and Bowen's disease (squamous cell carcinoma).


See also

* Electrology


Further reading

*


References

{{DEFAULTSORT:Intense Pulsed Light Hair removal