Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component
cells
Cell most often refers to:
* Cell (biology), the functional basic unit of life
Cell may also refer to:
Locations
* Monastic cell, a small room, hut, or cave in which a religious recluse lives, alternatively the small precursor of a monastery w ...
.
It is distinguished from
hyperplasia
Hyperplasia (from ancient Greek ὑπέρ ''huper'' 'over' + πλάσις ''plasis'' 'formation'), or hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount of organic tissue that results from cell proliferatio ...
, in which the cells remain approximately the same size but increase in number.
[Updated by Linda J. Vorvick. 8/14/1]
Hyperplasia
/ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally-induced proliferation and enlargement of the cells of the uterus
The uterus (from Latin ''uterus'', plural ''uteri'') or womb () is the organ in the reproductive system of most female mammals, including humans that accommodates the embryonic and fetal development of one or more embryos until birth. The ...
during pregnancy
Pregnancy is the time during which one or more offspring develops ( gestates) inside a woman's uterus (womb). A multiple pregnancy involves more than one offspring, such as with twins.
Pregnancy usually occurs by sexual intercourse, but ...
.
Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the left ventricle
A ventricle is one of two large chambers toward the bottom of the heart that collect and expel blood towards the peripheral beds within the body and lungs. The blood pumped by a ventricle is supplied by an atrium, an adjacent chamber in the uppe ...
of heart. Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast to hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which the heart becomes thickened without an obvious cause. The parts of the heart most commonly affected are the interventricular septum and the ventricles. This r ...
, a type of concentric hypertrophy
Concentric hypertrophy is a hypertrophic growth of a hollow organ without overall enlargement, in which the walls of the organ are thickened and its capacity or volume is diminished.
Sarcomeres are added in parallel, as for example occurs in hype ...
, where sarcomeres are added in parallel).
Gallery
File:*+ * Photographic documentation on sexual education - Hypertrophy of breast - Nude of an elderly woman around 1870 - Photographer unknown - Public domain, since the copyright has expired;.jpg, Hypertrophy of breast
The breast is one of two prominences located on the upper ventral region of a primate's torso. Both females and males develop breasts from the same embryological tissues.
In females, it serves as the mammary gland, which produces and sec ...
, c. 1870
File:Hypertrophied clitoris.jpg, Hypertrophy of the clitoris
The clitoris ( or ) is a female sex organ present in mammals, ostriches and a limited number of other animals. In humans, the visible portion – the glans – is at the front junction of the labia minora (inner lips), above the op ...
File:Feet from a case of partial hypertrophy of the foot Wellcome L0061374.jpg, Hypertrophy of the foot
The foot ( : feet) is an anatomical structure found in many vertebrates. It is the terminal portion of a limb which bears weight and allows locomotion. In many animals with feet, the foot is a separate organ at the terminal part of the leg mad ...
, partial
File:Ipertrofia miocardica.jpg, Forensic post-mortem examination of a case of hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which the heart becomes thickened without an obvious cause. The parts of the heart most commonly affected are the interventricular septum and the ventricles. This r ...
, showing thickening of the cardiac muscle
Cardiac muscle (also called heart muscle, myocardium, cardiomyocytes and cardiac myocytes) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle. It is an involuntary, striated muscle ...
File:Head of a boy with hypertrophy of the ear Wellcome L0062496.jpg, Hypertrophy of the ear ( macrotia)
File:Kidney hypertrophy Wellcome L0005308.jpg, Kidney hypertrophy
File:Lip hypertrophy.jpg, Hypertrophy of the upper lip
File:Face of man with hypertrophy of the temporal muscles Wellcome L0062508.jpg, Hypertrophy of the temporal muscles
See also
* Athlete's heart
* Ventricular hypertrophy (including left ventricular hypertrophy and right ventricular hypertrophy)
* Muscle hypertrophy
Muscle hypertrophy or muscle building involves a hypertrophy or increase in size of skeletal muscle through a growth in size of its component cells. Two factors contribute to hypertrophy: sarcoplasmic hypertrophy, which focuses more on increas ...
* List of biological development disorders
References
External links
University of California Muscle Physiology Home Page: Hypertrophy
{{Pathology
Muscular system
Tissues (biology)
Exercise physiology
Physical exercise
Anatomical pathology