3,3'-Dinitrobisphenol A is an
organic compound
In chemistry, organic compounds are generally any chemical compounds that contain carbon-hydrogen or carbon-carbon bonds. Due to carbon's ability to catenate (form chains with other carbon atoms), millions of organic compounds are known. T ...
with the formula (HO(O
2N)C
6H
3)
2C(CH
3)
2. It is a yellow-orange solid prepared by
nitration
In organic chemistry, nitration is a general class of chemical processes for the introduction of a nitro group into an organic compound. The term also is applied incorrectly to the different process of forming nitrate esters between alcohols an ...
of
bisphenol A
Carcinogenicity
It has been proposed that dinitrobisphenol A might be formed ''in vivo'' by
peroxynitrite
Peroxynitrite (sometimes called peroxonitrite) is an ion with the formula ONOO−. It is a structural isomer of nitrate,
Preparation
Peroxynitrite can be prepared by the reaction of superoxide with nitric oxide:
:
It is prepared by the react ...
mediated oxidations of bisphenol A and that it may exhibit higher toxicity than BPA itself.
3,3'-Dinitrobisphenol A is found to be
genotoxic Genotoxicity is the property of chemical agents that damage the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, but some genotoxic s ...
in male ICR mice on a micronucleus test.
Its
estrogenic potential is not known however it has shown some binding to estrogen-related receptor gamma to an extent.
See also
*
Bisphenol A
*
Tetrabromobisphenol A
Tetrabromobisphenol A (TBBPA) is a brominated flame retardant. The compound is a white solid (not colorless), although commercial samples appear yellow. It is one of the most common flame retardants.
Production and use
TBBPA is produced by the ...
References
{{Reflist
2,2-Bis(4-hydroxyphenyl)propanes
Nitro compounds