A cranial nerve nucleus is a collection of

neuron A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa ...

s (

gray matter Grey matter is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells (astrocytes and oligodendrocytes), synapses, and capillaries. Grey matter is distingui ...

) in the

brain stem The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is co ...

that is associated with one or more of the

cranial nerves Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), of which there are conventionally considered twelve pairs. Cranial nerves relay information between the brain and parts of the body, primarily to and f ...

Axon An axon (from Greek ἄξων ''áxōn'', axis), or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action p ...

s carrying information to and from the cranial nerves form a

synapse In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to the transmission of nervous impulses from ...

first at these nuclei. Lesions occurring at these nuclei can lead to effects resembling those seen by the severing of nerve(s) they are associated with. All the nuclei except that of the

trochlear nerve The trochlear nerve (), ( lit. ''pulley-like'' nerve) also known as the fourth cranial nerve, cranial nerve IV, or CN IV, is a cranial nerve that innervates just one muscle: the superior oblique muscle of the eye, which operates through the pu ...

(CN IV) supply nerves of the same side of the body.

Structure

Motor and sensory

In general, motor nuclei are closer to the front (

ventral Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position prov ...

), and sensory nuclei and neurons are closer to the back (

dorsal Dorsal (from Latin ''dorsum'' ‘back’) may refer to: * Dorsal (anatomy), an anatomical term of location referring to the back or upper side of an organism or parts of an organism * Dorsal, positioned on top of an aircraft's fuselage * Dorsal c ...

). This arrangement mirrors the arrangement of tracts in the

spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue, which extends from the medulla oblongata in the brainstem to the lumbar region of the vertebral column (backbone). The backbone encloses the central canal of the sp ...

. * Close to the midline are the

motor efferent nuclei The general (spinal) somatic efferent neurons (GSE, somatomotor, or somatic motor fibers), arise from motor neuron cell bodies in the ventral horns of the gray matter within the spinal cord. They exit the spinal cord through the ventral roots, ca ...

, such as the

oculomotor nucleus The fibers of the oculomotor nerve arise from a nucleus in the midbrain, which lies in the gray substance of the floor of the cerebral aqueduct and extends in front of the aqueduct for a short distance into the floor of the third ventricle. From t ...

, which control skeletal muscle. Just lateral to this are the autonomic (or visceral) efferent nuclei. * There is a separation, called the sulcus limitans, and lateral to this are the sensory nuclei. Near the sulcus limitans are the visceral afferent nuclei, namely the

solitary tract nucleus In the human brainstem, the solitary nucleus, also called nucleus of the solitary tract, nucleus solitarius, and nucleus tractus solitarii, (SN or NTS) is a series of purely sensory nuclei (clusters of nerve cell bodies) forming a vertical column ...

. * More lateral, but also less posterior, are the

general somatic afferent The general somatic afferent fibers (GSA, or somatic sensory fibers) afferent fibers arise from neurons in sensory ganglia and are found in all the spinal nerves, except occasionally the first cervical, and conduct impulses of pain, touch and temp ...

nuclei. This is the trigeminal nucleus. Back at the dorsal surface of the brainstem, and more lateral are the special somatic afferents, this handles sensation such as balance. * Another area, not on the dorsum of the brainstem, is where the

special visceral efferents Special visceral efferent fibers (SVE) are the efferent nerve fibers that provide motor innervation to the muscles of the pharyngeal arches in humans, and the branchial arches in fish. Some sources prefer the term "branchiomotor" or "branchial e ...

nuclei reside. These formed from the

pharyngeal arch The pharyngeal arches, also known as visceral arches'','' are structures seen in the embryonic development of vertebrates that are recognisable precursors for many structures. In fish, the arches are known as the branchial arches, or gill arche ...

es, in the embryo. This area is a bit below the autonomic motor nuclei, and includes the

nucleus ambiguus The nucleus ambiguus ("ambiguous nucleus" in English) is a group of large motor neurons, situated deep in the medullary reticular formation named by Jacob Clarke. The nucleus ambiguus contains the cell bodies of neurons that innervate the muscle ...

facial nerve The facial nerve, also known as the seventh cranial nerve, cranial nerve VII, or simply CN VII, is a cranial nerve that emerges from the pons of the brainstem, controls the muscles of facial expression, and functions in the conveyance of taste ...

nucleus, as well as the motor part of the

trigeminal nerve In neuroanatomy, the trigeminal nerve ( lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for sensation in the face and motor functions such as biting and che ...

nucleus.

Location

This list documents nuclei by the part of the brain they are found in: *

Red nucleus The red nucleus or nucleus ruber is a structure in the rostral midbrain involved in motor coordination. The red nucleus is pale pink, which is believed to be due to the presence of iron in at least two different forms: hemoglobin and ferritin. ...

- motor, extrapyramidal * Trochlear nucleus (IV) - motor *

Oculomotor nucleus The fibers of the oculomotor nerve arise from a nucleus in the midbrain, which lies in the gray substance of the floor of the cerebral aqueduct and extends in front of the aqueduct for a short distance into the floor of the third ventricle. From t ...

(III) - motor * Edinger-Westphal nucleus (III) - visceromotor *

Cochlear nuclei The cochlear nuclear (CN) complex comprises two cranial nerve nuclei in the human brainstem, the ventral cochlear nucleus (VCN) and the dorsal cochlear nucleus (DCN). The ventral cochlear nucleus is unlayered whereas the dorsal cochlear nucleus ...

(VIII) - sensory ** Dorsal cochlear nucleus ** Ventral cochlear nucleus *

Vestibular nuclei The vestibular nuclei (VN) are the cranial nuclei for the vestibular nerve located in the brainstem. In Terminologia Anatomica they are grouped in both the pons and the medulla in the brainstem. Structure Path The fibers of the vestibular n ...

(VIII) - sensory * Salivary nuclei - visceromotor **

Inferior salivary nucleus The salivatory nuclei are the superior salivatory nucleus, and the inferior salivatory nucleus that innervate the salivary glands. They are located in the pontine tegmentum in the brainstem. They both are examples of cranial nerve nuclei. The s ...

(IX) ** Superior salivary nucleus (VII) *

Facial nucleus The facial motor nucleus is a collection of neurons in the brainstem that belong to the facial nerve (cranial nerve VII). These lower motor neurons innervate the muscles of facial expression and the stapedius. Structure The nucleus is situated i ...

(VII) - motor *

Abducens nucleus The abducens nucleus is the originating nucleus from which the abducens nerve (VI) emerges—a cranial nerve nucleus. This nucleus is located beneath the fourth ventricle in the caudal portion of the pons, medial to the sulcus limitans. The abd ...

(VI) - motor * Trigeminal motor nucleus (V) - motor * Main trigeminal nucleus (V) - sensory (fine touch and vibration) Medulla oblongata - posterior - low mag

* Hypoglossal nucleus (XII) - motor *

Dorsal motor nucleus of vagus nerve The dorsal nucleus of vagus nerve (or posterior nucleus of vagus nerve or dorsal vagal nucleus or nucleus dorsalis nervi vagi or nucleus posterior nervi vagi) is a cranial nerve nucleus for the vagus nerve in the medulla that lies ventral to the ...

(X) - visceromotor *

Nucleus ambiguus The nucleus ambiguus ("ambiguous nucleus" in English) is a group of large motor neurons, situated deep in the medullary reticular formation named by Jacob Clarke. The nucleus ambiguus contains the cell bodies of neurons that innervate the muscle ...

(IX, X, XI) - motor *

Solitary nucleus In the human brainstem, the solitary nucleus, also called nucleus of the solitary tract, nucleus solitarius, and nucleus tractus solitarii, (SN or NTS) is a series of purely sensory nuclei (clusters of nerve cell bodies) forming a vertical column ...

(VII, IX, X) - sensory * Spinal trigeminal nucleus (V) - sensory (crude touch, temperature and pain) * Inferior olivary nucleus afferent fibres to cerebellum

Location

References

Lennart Heimer Lennart Heimer (11 March 1930 – 12 March 2007), was a Swedish-American neuroscientist and professor at the Massachusetts Institute of Technology and the University of Virginia. He was most noted for mapping circuits of the brain in the limbic ...

, ''The Human Brain'',

Additional images

File:Gray697.png, Nuclei of origin of cranial motor nerves schematically represented; lateral view. File:Gray698.png, Primary terminal nuclei of the afferent (sensory) cranial nerves schematically represented; lateral view. File:Brain stem sagittal section.svg, Brain stem sagittal section

External links

*
Slides at Colorado College
{{Authority control Brainstem