Chromosome engineering is "the controlled generation of chromosomal deletions, inversions, or translocations with defined endpoints." By combining
chromosomal translocation
In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation, with two main types: reciprocal-, and Robertsonian translocation. Reciprocal translo ...
,
chromosomal inversion, and
chromosomal deletion, chromosome engineering has been shown to identify the underlying genes that cause certain diseases in mice. In coming years, it is very likely that chromosomal engineering will be able to do the same identification for diseases in humans, as well as all other organisms.
The Three Types of Chromosome Engineering
Experiments of Chromosome Engineering
In an experiment pertaining to chromosome engineering that was conducted in 2006, it was found that chromosome engineering can be effectively used as a method of identifying the causes of genetic disorders such as the continuous gene and aneuploidy syndromes. The experiment was conducted by infecting mice with the human disease, ES, to see the effectiveness of chromosomal engineering in the gene identification of those diseases. After much experimenting, it was found that manipulating chromosomes, or chromosome engineering, is an excellent and efficient method of determining underlying genes in genetic orders and diseases.
In the future, chromosome engineering will experiment in removing more common disorders such as asthma, diabetes, and cancer. If it can be recognized by the medical community as effective and safe, it should be able to be used regularly in the near future.
See also
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar wor ...
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Chromosome
A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are ...
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Chromosomal deletion
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Chromosomal inversion
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Chromosomal translocation
In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation, with two main types: reciprocal-, and Robertsonian translocation. Reciprocal translo ...
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DNA
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Disease
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
References
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DNA
Chromosomes