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Brominated vegetable oil (BVO) is a complex mixture of plant-derived
triglycerides A triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids (from ''tri-'' and ''glyceride''). Triglycerides are the main constituents of body fat in humans and other vertebrates, as we ...
that have been reacted to contain atoms of the element
bromine Bromine is a chemical element with the symbol Br and atomic number 35. It is the third-lightest element in group 17 of the periodic table ( halogens) and is a volatile red-brown liquid at room temperature that evaporates readily to form a simi ...
bonded to the molecules. Brominated vegetable oil is used primarily to help
emulsify An emulsion is a mixture of two or more liquids that are normally immiscible (unmixable or unblendable) owing to liquid-liquid phase separation. Emulsions are part of a more general class of two-phase systems of matter called colloids. Althoug ...
citrus ''Citrus'' is a genus of flowering trees and shrubs in the rue family, Rutaceae. Plants in the genus produce citrus fruits, including important crops such as oranges, lemons, grapefruits, pomelos, and limes. The genus ''Citrus'' is native to ...
-flavored
soft drinks A soft drink (see #Terminology, § Terminology for other names) is a drink that usually contains water (often Carbonated water, carbonated), a Sweetness, sweetener, and a natural and/or Artificial Flavoring, artificial flavoring. The sweetene ...
, preventing them from separating during distribution. Brominated vegetable oil has been used by the soft drink industry since 1931, generally at a level of about 8  ppm. Careful control of the type of oil used allows bromination of it to produce BVO with a specific
density Density (volumetric mass density or specific mass) is the substance's mass per unit of volume. The symbol most often used for density is ''ρ'' (the lower case Greek letter rho), although the Latin letter ''D'' can also be used. Mathematicall ...
of 1.33 g/mL, which is noticeably greater than that of water (1 g/mL). As a result, it can be mixed with less-dense flavoring agents such as citrus flavor oil to produce a resulting oil, the density of which matches that of water or other products. The droplets containing BVO remain suspended in the water rather than separating and floating at the surface. Alternative
food additives Food additives are substances added to food to preserve flavor or enhance taste, appearance, or other sensory qualities. Some additives have been used for centuries as part of an effort to preserve food, for example vinegar (pickling), salt (sal ...
used for the same purpose include sucrose acetate isobutyrate (SAIB, E444) and glycerol ester of wood rosin (ester gum, E445).


Regulation and use


United States

In the United States, BVO was designated in 1958 as generally recognized as safe (GRAS), but this was withdrawn by the U.S. Food and Drug Administration in 1970. The U.S.
Code of Federal Regulations In the law of the United States, the ''Code of Federal Regulations'' (''CFR'') is the codification of the general and permanent regulations promulgated by the executive departments and agencies of the federal government of the United States. ...
currently imposes restrictions on the use of BVO as a
food additive Food additives are substances added to food to preserve Taste, flavor or enhance taste, appearance, or other sensory qualities. Some additives have been used for centuries as part of an effort to preserve food, for example vinegar (pickling), sal ...
in the
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country Continental United States, primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., ...
, limiting the concentration to 15 ppm, limiting the amount of free
fatty acid In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, f ...
s to 2.5 percent, and limiting the iodine value to 16. An online petition at Change.org asking PepsiCo to stop adding BVO to Gatorade and other products collected over 200,000 signatures by January 2013. The petition pointed out that since Gatorade is sold in countries where BVO is not approved, there is already an existing formulation without this ingredient. PepsiCo announced in January 2013 that it would no longer use BVO in Gatorade. On May 5, 2014,
Coca-Cola Coca-Cola, or Coke, is a carbonated soft drink manufactured by the Coca-Cola Company. Originally marketed as a temperance bar, temperance drink and intended as a patent medicine, it was invented in the late 19th century by John Stith Pembe ...
and
PepsiCo PepsiCo, Inc. is an American multinational food, snack, and beverage corporation headquartered in Harrison, New York, in the hamlet of Purchase. PepsiCo's business encompasses all aspects of the food and beverage market. It oversees the manufa ...
said they would remove BVO from their products. As of 2020,
Mountain Dew Mountain Dew, stylized as Mtn Dew, is a carbonated soft drink brand produced and owned by PepsiCo. The original formula was invented in 1940 by Tennessee beverage bottlers Barney and Ally Hartman. A revised formula was created by Bill Brid ...
, manufactured by
PepsiCo PepsiCo, Inc. is an American multinational food, snack, and beverage corporation headquartered in Harrison, New York, in the hamlet of Purchase. PepsiCo's business encompasses all aspects of the food and beverage market. It oversees the manufa ...
, no longer uses BVO in the main line of beverages, but the original BVO-containing formula is still sometimes sold as the lesser distributed " Mountain Dew Throwback" beverage. BVO is used in Sun Drop, made by the
Dr Pepper Snapple Group Dr Pepper Snapple Group (also called Dr. Pepper/7up Inc.) was an American multinational soft drink company based in Plano, Texas, and as of July 2018 it is a business unit of the publicly traded conglomerate Keurig Dr Pepper. Formerly Cadbury S ...
. Numerous
generic citrus sodas In addition to PepsiCo's Mountain Dew, Coca-Cola's Mello Yello or Dr Pepper's Sun Drop, there are a variety of smaller or regional brands for citrus soda. Several of these brands include the word "Mountain" in their name to help describe th ...
also use it, including; "Mountain Lightning"/
Walmart Walmart Inc. (; formerly Wal-Mart Stores, Inc.) is an American multinational retail corporation that operates a chain of hypermarkets (also called supercenters), discount department stores, and grocery stores from the United States, headquarter ...
sodas, "Clover Valley"/
Dollar General Dollar General Corporation is an American chain of variety stores headquartered in Goodlettsville, Tennessee. As of April 11, 2022, Dollar General operates 18,216 stores in the continental United States. The company began in 1939 as a family- ...
sodas, "Orangette" and Stars & Stripes. BVO is much less frequently used as an emulsifier in non-
carbonated Carbonation is the chemical reaction of carbon dioxide to give carbonates, bicarbonates, and carbonic acid. In chemistry, the term is sometimes used in place of carboxylation, which refers to the formation of carboxylic acids. In inorganic ch ...
drinks, such as flavoring syrups for caffeinated beverages and specialty juices. BVO is one of four substances that the U.S. Food and Drug Administration has defined as interim food additives; the other three are
acrylonitrile Acrylonitrile is an organic compound with the formula and the structure . It is a colorless, volatile liquid although commercial samples can be yellow due to impurities. It has a pungent odor of garlic or onions. In terms of its molecula ...
copolymer In polymer chemistry, a copolymer is a polymer derived from more than one species of monomer. The polymerization of monomers into copolymers is called copolymerization. Copolymers obtained from the copolymerization of two monomer species are ...
s,
mannitol Mannitol is a type of sugar alcohol used as a sweetener and medication. It is used as a low calorie sweetener as it is poorly absorbed by the intestines. As a medication, it is used to decrease pressure in the eyes, as in glaucoma, and to lo ...
, and
saccharin Saccharin (''aka'' saccharine, Sodium sacchari) is an artificial sweetener with effectively no nutritional value. It is about 550 times as sweet as sucrose but has a bitter or metallic aftertaste, especially at high concentrations. Saccharin is ...
.


Canada

BVO is currently permitted as a food additive in Canada, but only in beverages containing citrus or spruce oils.


Europe

In the
European Union The European Union (EU) is a supranational union, supranational political union, political and economic union of Member state of the European Union, member states that are located primarily in Europe, Europe. The union has a total area of ...
, BVO is banned from use as a food additive; and any BVO-containing products that may slip through the regulations are pulled from shelves upon discovery. In the EU, beverage companies commonly use glycerol ester of wood rosin or locust bean gum as an alternative to BVO.


India

Standards for
soft drink A soft drink (see § Terminology for other names) is a drink A drink or beverage is a liquid intended for human consumption. In addition to their basic function of satisfying thirst, drinks play important roles in human culture. Common t ...
s in
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area, the List of countries and dependencies by population, second-most populous ...
have prohibited the use of BVO since 1990.


Japan

The use of BVO as a food additive has been banned in Japan since 2010.


Health effects

There are case reports of adverse effects associated with excessive consumption of BVO-containing products. One case reported that a man who consumed two to four liters of a soda containing BVO on a daily basis experienced memory loss, tremors, fatigue, loss of muscle coordination, headache, and ptosis of the right eyelid, as well as elevated serum chloride. In the two months it took to correctly diagnose the problem, the patient also lost the ability to walk. Eventually, bromism was diagnosed and
hemodialysis Hemodialysis, also spelled haemodialysis, or simply dialysis, is a process of purifying the blood of a person whose kidneys are not working normally. This type of dialysis achieves the extracorporeal removal of waste products such as creatinin ...
was prescribed which resulted in a reversal of the disorder.


References

{{reflist, 2


External links


Brominated Battle: Soda Chemical Has Cloudy Health History



Behavioral and reproductive effects of chronic developmental exposure to brominated vegetable oil in rats

FDA Everything Added to Food in the United States (EAFUS) entry for brominated vegetable oil

Gesundheitliche Bewertung von Erfrischungsgetränken mit zugesetzten bromierten Pflanzenölen. Stellungnahme Nr. 023/2014 des Bundesinstituts für Risikobewertung vom 4. Juli 2014
Food emulsifiers Vegetable oils Bromine