Acetyltransferase (or transacetylase) is a type of
transferase
A transferase is any one of a class of enzymes that catalyse the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor). They are involved in hundreds o ...
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
that transfers an
acetyl
In organic chemistry, acetyl is a functional group with the chemical formula and the structure . It is sometimes represented by the symbol Ac (not to be confused with the element actinium). In IUPAC nomenclature, acetyl is called ethanoyl, ...
group.
Examples include:
*
Histone acetyltransferase
Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA to form ε-''N''-acetyllysine. DNA is wrapped around histones, and, by transferring an ...
s including
CBP histone acetyltransferase
*
Choline acetyltransferase
Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. ChAT catalyzes the transfer of an acetyl group from the coenzyme acetyl-Co ...
*
Chloramphenicol acetyltransferase
*
Serotonin N-acetyltransferase
*
NatA Acetyltransferase
*
NatB acetyltransferase
See also
*
Acyltransferase
Acyltransferase is a type of transferase enzyme that acts upon acyl groups.
Examples include:
* Glyceronephosphate O-acyltransferase
* Lecithin-cholesterol acyltransferase
* Long-chain-alcohol O-fatty-acyltransferase
See also
* Acetyltransferas ...
*
Acetylation
:
In organic chemistry, acetylation is an organic esterification reaction with acetic acid. It introduces an acetyl group into a chemical compound. Such compounds are termed ''acetate esters'' or simply '' acetates''. Deacetylation is the oppos ...
External links
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Transferases
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