W.D. Halliburton
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William Dobinson Halliburton FRS (21 June 1860, in
Middlesex Middlesex (; abbreviation: Middx) is a historic county in southeast England. Its area is almost entirely within the wider urbanised area of London and mostly within the ceremonial county of Greater London, with small sections in neighbour ...
– 21 May 1931, in Exeter) was a British physiologist, noted for being one of the founders of the science of
biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
. William was one of four children (three sisters) born to Thomas Gill Halliburton and Mary Strachan Homan of
Middlesex Middlesex (; abbreviation: Middx) is a historic county in southeast England. Its area is almost entirely within the wider urbanised area of London and mostly within the ceremonial county of Greater London, with small sections in neighbour ...
. He was educated at the
University College School ("Slowly but surely") , established = , closed = , type = Public schoolIndependent day school , religion = , president = , head_label = Headmaster , head = Mark Beard , r_head_label = , r_he ...
and later at the
University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...
, obtaining a
BSc A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University ...
in 1879. On his MRCS in 1883 he was appointed Assistant in Physiology at the University College under Sir Edward Sharpey-Schafer. His MD followed in 1884, his membership of the
Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 ...
a year later and his Fellowship in 1892. Halliburton succeeded Gerald Francis Yeo in the chair of Physiology at King's College London in 1889. Over the period of 34 years at King's College he was deeply involved in its administration and was dean of the Faculty of Medical Science for many years. In 1923 his chronic ill-health obliged him to resign from the chair and accept the sinecure of Emeritus Professor. During his tenure at King's College, he assembled a research team, many of whom later became distinguished clinicians, including such figures as Thomas Gregor Brodie (1866-1916), Frank S. Locke, Sir Charles James Martin (1866-1955), Sir
Frederick Walker Mott Sir Frederick Walker Mott (23 October 1853 in Brighton, Sussex – 8 June 1926 in Birmingham, Warwickshire) was one of the pioneers of biochemistry in Britain. He is noted for his work in neuropathology and endocrine glands in relation to menta ...
(1853–1926), Walter Ernest Dixon (1871–1931), Sigmund Otto Rosenheim (1871–1955) and Corrado Donato Da Fano (1879-1927). He and Rosenheim discovered that
cholesterol Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
was not pure, but contained ergosterol which led to the formation of
Vitamin D Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects. In humans, the most important compounds in this group are vitamin D3 (c ...
under
ultraviolet Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 nm (with a corresponding frequency around 30  PHz) to 400 nm (750  THz), shorter than that of visible light, but longer than X-rays. UV radiation ...
light. Halliburton's first laboratory was improvised in a disused corridor, but nonetheless became the meeting place of the keenest minds in the infant science of biochemistry. His early research centered on the proteins making up muscle and blood, leading to his election as a
Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathemat ...
in 1891. Together with Walter Ernest Dixon he studied
cerebral circulation Cerebral circulation is the movement of blood through a network of cerebral arteries and veins supplying the brain. The rate of cerebral blood flow in an adult human is typically 750 milliliters per minute, or about 15% of cardiac output. Art ...
and
cerebrospinal fluid Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialised ependymal cells in the choroid plexus of the ventricles of the ...
. During this time he helped found the
Biochemical Society The Biochemical Society is a learned society in the United Kingdom in the field of biochemistry, including all the cellular and molecular biosciences. Structure It currently has around 7000 members, two-thirds in the UK. It is affiliated with th ...
of which he was the sole honorary member. Halliburton's name was a celebrated one in the field of medical literature. His writings were detailed and lucid, resulting in textbooks which were valued by students all over the world. The first of these was his ''"Textbook of Chemical Physiology and Pathology"'' published in 1891, in which he assembled all knowledge of the subject at the time. He rewrote ''" Kirkes' Physiology"'' completely in 1896 so that it subsequently, through its numerous editions, became known as ''"Halliburton's Physiology"'' and an indispensable reference work for legions of medical students. It became popular enough for an American publisher to flout copyright laws and to publish and sell unauthorised editions.''British Medical Journal'', 1900
/ref> Halliburton died after falling ill on a holiday to
Cornwall Cornwall (; kw, Kernow ) is a historic county and ceremonial county in South West England. It is recognised as one of the Celtic nations, and is the homeland of the Cornish people. Cornwall is bordered to the north and west by the Atlantic ...
, which forced him to have an unsuccessful operation at an Exeter clinic. He is buried at
Highgate Cemetery Highgate Cemetery is a place of burial in north London, England. There are approximately 170,000 people buried in around 53,000 graves across the West and East Cemeteries. Highgate Cemetery is notable both for some of the people buried there as ...
.


References


External links

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List of Fellows of the Royal Society (1660-2007)

Genealogy
{{DEFAULTSORT:Halliburton, William Dobinson 1860 births 1931 deaths Burials at Highgate Cemetery People educated at University College School Alumni of University College London Academics of King's College London Fellows of the Royal Society British physiologists British biochemists